Monogenic early-onset lymphoproliferation and autoimmunity: Natural history of STAT3 gain-of-function syndrome

STAT3 GOF; Jennifer W. Leiding; Tiphanie P. Vogel; Valentine G. J. Santarlas; Mervi Taskinen; Kaarina Heiskanen; Timi Martelius; Mikko R. J. Seppänen

doi:10.1016/j.jaci.2022.09.002

Monogenic early-onset lymphoproliferation and autoimmunity: Natural history of STAT3 gain-of-function syndrome

STAT3 GOF, Jennifer W. Leiding, Tiphanie P. Vogel, Valentine G. J. Santarlas, Mervi Taskinen, Kaarina Heiskanen, Timi Martelius, Mikko R. J. Seppänen

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	Journal of Allergy and Clinical Immunology
Volume	151
Issue number	4
Pages (from-to)	1081-1095
Number of pages	15
ISSN	0091-6749
DOIs	https://doi.org/10.1016/j.jaci.2022.09.002
Publication status	Published - Apr 2023
MoE publication type	A1 Journal article-refereed

Fields of Science

3121 General medicine, internal medicine and other clinical medicine

Access to Document

10.1016/j.jaci.2022.09.002

Cite this

@article{d6808d89326a479ca17e623712bc7d72,

title = "Monogenic early-onset lymphoproliferation and autoimmunity: Natural history of STAT3 gain-of-function syndrome",

keywords = "Stat3, Autoimmunity, Cytopenia, Gain of function, Immune dysregulation, Immunodeficiency, Lymphoproliferation, Precision medicine, 3121 General medicine, internal medicine and other clinical medicine",

author = "{STAT3 GOF} and Leiding, {Jennifer W.} and Vogel, {Tiphanie P.} and Santarlas, {Valentine G. J.} and Rahul Mhaskar and Smith, {Madison R.} and Alexandre Carisey and Alexander Vargas-Hernandez and Manuel Silva-Carmona and Maximilian Heeg and Anne Rensing-Ehl and Benedicte Neven and Jerome Hadjadj and Sophie Hambleton and Leahy, {Timothy Ronan} and Kornvalee Meesilpavikai and Charlotte Cunningham-Rundles and Dutmer, {Cullen M.} and Sharapova, {Svetlana O.} and Mervi Taskinen and Ignatius Chua and Rosie Hague and Christian Klemann and Larysa Kostyuchenko and Tomohiro Morio and Akaluck Thatayatikom and Ahmet Ozen and Anna Scherbina and Bauer, {Cindy S.} and Flanagan, {Sarah E.} and Eleonora Gambineri and Lisa Giovannini-Chami and Jennifer Heimall and Sullivan, {Kathleen E.} and Eric Allenspach and Nei Romberg and Deane, {Sean G.} and Prince, {Benjamin T.} and Rose, {Melissa J.} and John Bohnsack and Talal Mousallem and Rohith Jesudas and Vilela, {Maria Marluce Dos Santos} and Michael O'Sullivan and Schmid, {Jana Pachlopnik} and Stepanka Pruhova and Adam Klocperk and Matthew Rees and Helen Su and Kaarina Heiskanen and Timi Martelius and Sepp{\"a}nen, {Mikko R. J.}",

year = "2023",

month = apr,

doi = "10.1016/j.jaci.2022.09.002",

language = "English",

volume = "151",

pages = "1081--1095",

journal = "Journal of Allergy and Clinical Immunology",

issn = "0091-6749",

publisher = "Mosby Elsevier",

number = "4",

}

TY - JOUR

T1 - Monogenic early-onset lymphoproliferation and autoimmunity

T2 - Natural history of STAT3 gain-of-function syndrome

AU - STAT3 GOF

AU - Leiding, Jennifer W.

AU - Vogel, Tiphanie P.

AU - Santarlas, Valentine G. J.

AU - Mhaskar, Rahul

AU - Smith, Madison R.

AU - Carisey, Alexandre

AU - Vargas-Hernandez, Alexander

AU - Silva-Carmona, Manuel

AU - Heeg, Maximilian

AU - Rensing-Ehl, Anne

AU - Neven, Benedicte

AU - Hadjadj, Jerome

AU - Hambleton, Sophie

AU - Leahy, Timothy Ronan

AU - Meesilpavikai, Kornvalee

AU - Cunningham-Rundles, Charlotte

AU - Dutmer, Cullen M.

AU - Sharapova, Svetlana O.

AU - Taskinen, Mervi

AU - Chua, Ignatius

AU - Hague, Rosie

AU - Klemann, Christian

AU - Kostyuchenko, Larysa

AU - Morio, Tomohiro

AU - Thatayatikom, Akaluck

AU - Ozen, Ahmet

AU - Scherbina, Anna

AU - Bauer, Cindy S.

AU - Flanagan, Sarah E.

AU - Gambineri, Eleonora

AU - Giovannini-Chami, Lisa

AU - Heimall, Jennifer

AU - Sullivan, Kathleen E.

AU - Allenspach, Eric

AU - Romberg, Nei

AU - Deane, Sean G.

AU - Prince, Benjamin T.

AU - Rose, Melissa J.

AU - Bohnsack, John

AU - Mousallem, Talal

AU - Jesudas, Rohith

AU - Vilela, Maria Marluce Dos Santos

AU - O'Sullivan, Michael

AU - Schmid, Jana Pachlopnik

AU - Pruhova, Stepanka

AU - Klocperk, Adam

AU - Rees, Matthew

AU - Su, Helen

AU - Heiskanen, Kaarina

AU - Martelius, Timi

AU - Seppänen, Mikko R. J.

PY - 2023/4

Y1 - 2023/4

KW - Stat3

KW - Autoimmunity

KW - Cytopenia

KW - Gain of function

KW - Immune dysregulation

KW - Immunodeficiency

KW - Lymphoproliferation

KW - Precision medicine

KW - 3121 General medicine, internal medicine and other clinical medicine

U2 - 10.1016/j.jaci.2022.09.002

DO - 10.1016/j.jaci.2022.09.002

M3 - Article

C2 - 36228738

SN - 0091-6749

VL - 151

SP - 1081

EP - 1095

JO - Journal of Allergy and Clinical Immunology

JF - Journal of Allergy and Clinical Immunology

IS - 4

ER -