Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks

Florence Demenais; Patricia Margaritte-Jeannin; Kathleen C. Barnes; William O. C. Cookson; Janine Altmueller; Wei Ang; R. Graham Barr; Terri H. Beaty; Allan B. Becker; John Beilby; Hans Bisgaard; Unnur Steina Bjornsdottir; Eugene Bleecker; Klaus Bonnelykke; Dorret I. Boomsma; Emmanuelle Bouzigon; Christopher E. Brightling; Myriam Brossard; Guy G. Brusselle; Esteban Burchard; Kristin M. Burkart; Andrew Bush; Moira Chan-Yeung; Kian Fan Chung; Alexessander Couto Alves; John A. Curtin; Adnan Custovic; Denise Daley; Johan C. de Jongste; Blanca E. Del-Rio-Navarro; Kathleen M. Donohue; Liesbeth Duijts; Celeste Eng; Johan G. Eriksson; Martin Farrall; Yuliya Fedorova; Bjarke Feenstra; Manuel A. Ferreira; Maxim B. Freidin; Zofia Gajdos; Jim Gauderman; Ulrike Gehring; Frank Geller; Jon Genuneit; Sina A. Gharib; Frank Gilliland; Tari Haahtela; Mikko Kuokkanen; Aarno Palotie; Elisabeth Widen; Australian Asthma Genetics Consort

doi:10.1038/s41588-017-0014-7

Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks

Florence Demenais, Patricia Margaritte-Jeannin, Kathleen C. Barnes, William O. C. Cookson, Janine Altmueller, Wei Ang, R. Graham Barr, Terri H. Beaty, Allan B. Becker, John Beilby, Hans Bisgaard, Unnur Steina Bjornsdottir, Eugene Bleecker, Klaus Bonnelykke, Dorret I. Boomsma, Emmanuelle Bouzigon, Christopher E. Brightling, Myriam Brossard, Guy G. Brusselle, Esteban BurchardKristin M. Burkart, Andrew Bush, Moira Chan-Yeung, Kian Fan Chung, Alexessander Couto Alves, John A. Curtin, Adnan Custovic, Denise Daley, Johan C. de Jongste, Blanca E. Del-Rio-Navarro, Kathleen M. Donohue, Liesbeth Duijts, Celeste Eng, Johan G. Eriksson, Martin Farrall, Yuliya Fedorova, Bjarke Feenstra, Manuel A. Ferreira, Maxim B. Freidin, Zofia Gajdos, Jim Gauderman, Ulrike Gehring, Frank Geller, Jon Genuneit, Sina A. Gharib, Frank Gilliland, Tari Haahtela, Mikko Kuokkanen, Aarno Palotie, Elisabeth Widen, Australian Asthma Genetics Consort

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	Nature Genetics
Volume	50
Issue number	1
Pages (from-to)	42-53
Number of pages	14
ISSN	1061-4036
DOIs	https://doi.org/10.1038/s41588-017-0014-7
Publication status	Published - Jan 2018
MoE publication type	A1 Journal article-refereed

Fields of Science

GENOME-WIDE ASSOCIATION
AUTOIMMUNE-DISEASE
HAY-FEVER
VARIANTS
METAANALYSIS
EXPRESSION
GENE
POPULATIONS
TWINS
3111 Biomedicine

Access to Document

10.1038/s41588-017-0014-7

Cite this

Demenais, F., Margaritte-Jeannin, P., Barnes, K. C., Cookson, W. O. C., Altmueller, J., Ang, W., Barr, R. G., Beaty, T. H., Becker, A. B., Beilby, J., Bisgaard, H., Bjornsdottir, U. S., Bleecker, E., Bonnelykke, K., Boomsma, D. I., Bouzigon, E., Brightling, C. E., Brossard, M., Brusselle, G. G., ... Australian Asthma Genetics Consort (2018). Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks. Nature Genetics, 50(1), 42-53. https://doi.org/10.1038/s41588-017-0014-7

@article{d29cb2b177f44527855e9b02fb468cb8,

title = "Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks",

keywords = "GENOME-WIDE ASSOCIATION, AUTOIMMUNE-DISEASE, HAY-FEVER, VARIANTS, METAANALYSIS, EXPRESSION, GENE, POPULATIONS, TWINS, 3111 Biomedicine",

author = "Florence Demenais and Patricia Margaritte-Jeannin and Barnes, {Kathleen C.} and Cookson, {William O. C.} and Janine Altmueller and Wei Ang and Barr, {R. Graham} and Beaty, {Terri H.} and Becker, {Allan B.} and John Beilby and Hans Bisgaard and Bjornsdottir, {Unnur Steina} and Eugene Bleecker and Klaus Bonnelykke and Boomsma, {Dorret I.} and Emmanuelle Bouzigon and Brightling, {Christopher E.} and Myriam Brossard and Brusselle, {Guy G.} and Esteban Burchard and Burkart, {Kristin M.} and Andrew Bush and Moira Chan-Yeung and Chung, {Kian Fan} and Alves, {Alexessander Couto} and Curtin, {John A.} and Adnan Custovic and Denise Daley and {de Jongste}, {Johan C.} and Del-Rio-Navarro, {Blanca E.} and Donohue, {Kathleen M.} and Liesbeth Duijts and Celeste Eng and Eriksson, {Johan G.} and Martin Farrall and Yuliya Fedorova and Bjarke Feenstra and Ferreira, {Manuel A.} and Freidin, {Maxim B.} and Zofia Gajdos and Jim Gauderman and Ulrike Gehring and Frank Geller and Jon Genuneit and Gharib, {Sina A.} and Frank Gilliland and Tari Haahtela and Mikko Kuokkanen and Aarno Palotie and Elisabeth Widen and {Australian Asthma Genetics Consort}",

year = "2018",

month = jan,

doi = "10.1038/s41588-017-0014-7",

language = "English",

volume = "50",

pages = "42--53",

journal = "Nature Genetics",

issn = "1061-4036",

publisher = "Nature Research ",

number = "1",

}

Demenais, F, Margaritte-Jeannin, P, Barnes, KC, Cookson, WOC, Altmueller, J, Ang, W, Barr, RG, Beaty, TH, Becker, AB, Beilby, J, Bisgaard, H, Bjornsdottir, US, Bleecker, E, Bonnelykke, K, Boomsma, DI, Bouzigon, E, Brightling, CE, Brossard, M, Brusselle, GG, Burchard, E, Burkart, KM, Bush, A, Chan-Yeung, M, Chung, KF, Alves, AC, Curtin, JA, Custovic, A, Daley, D, de Jongste, JC, Del-Rio-Navarro, BE, Donohue, KM, Duijts, L, Eng, C, Eriksson, JG, Farrall, M, Fedorova, Y, Feenstra, B, Ferreira, MA, Freidin, MB, Gajdos, Z, Gauderman, J, Gehring, U, Geller, F, Genuneit, J, Gharib, SA, Gilliland, F, Haahtela, T , Kuokkanen, M , Palotie, A , Widen, E & Australian Asthma Genetics Consort 2018, 'Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks', Nature Genetics, vol. 50, no. 1, pp. 42-53. https://doi.org/10.1038/s41588-017-0014-7

TY - JOUR

T1 - Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks

AU - Demenais, Florence

AU - Margaritte-Jeannin, Patricia

AU - Barnes, Kathleen C.

AU - Cookson, William O. C.

AU - Altmueller, Janine

AU - Ang, Wei

AU - Barr, R. Graham

AU - Beaty, Terri H.

AU - Becker, Allan B.

AU - Beilby, John

AU - Bisgaard, Hans

AU - Bjornsdottir, Unnur Steina

AU - Bleecker, Eugene

AU - Bonnelykke, Klaus

AU - Boomsma, Dorret I.

AU - Bouzigon, Emmanuelle

AU - Brightling, Christopher E.

AU - Brossard, Myriam

AU - Brusselle, Guy G.

AU - Burchard, Esteban

AU - Burkart, Kristin M.

AU - Bush, Andrew

AU - Chan-Yeung, Moira

AU - Chung, Kian Fan

AU - Alves, Alexessander Couto

AU - Curtin, John A.

AU - Custovic, Adnan

AU - Daley, Denise

AU - de Jongste, Johan C.

AU - Del-Rio-Navarro, Blanca E.

AU - Donohue, Kathleen M.

AU - Duijts, Liesbeth

AU - Eng, Celeste

AU - Eriksson, Johan G.

AU - Farrall, Martin

AU - Fedorova, Yuliya

AU - Feenstra, Bjarke

AU - Ferreira, Manuel A.

AU - Freidin, Maxim B.

AU - Gajdos, Zofia

AU - Gauderman, Jim

AU - Gehring, Ulrike

AU - Geller, Frank

AU - Genuneit, Jon

AU - Gharib, Sina A.

AU - Gilliland, Frank

AU - Haahtela, Tari

AU - Kuokkanen, Mikko

AU - Palotie, Aarno

AU - Widen, Elisabeth

AU - Australian Asthma Genetics Consort

PY - 2018/1

Y1 - 2018/1

KW - GENOME-WIDE ASSOCIATION

KW - AUTOIMMUNE-DISEASE

KW - HAY-FEVER

KW - VARIANTS

KW - METAANALYSIS

KW - EXPRESSION

KW - GENE

KW - POPULATIONS

KW - TWINS

KW - 3111 Biomedicine

U2 - 10.1038/s41588-017-0014-7

DO - 10.1038/s41588-017-0014-7

M3 - Article

SN - 1061-4036

VL - 50

SP - 42

EP - 53

JO - Nature Genetics

JF - Nature Genetics

IS - 1

ER -