Multiomics links global surfactant dysregulation with airflow obstruction and emphysema in COPD

Ventzislava A. Hristova; Alastair Watson; Raghothama Chaerkady; Matthew S. Glover; Jodie Ackland; Bastian Angerman; Graham Belfield; Maria G. Belvisi; Hannah Burke; Doriana Cellura; Howard W. Clark; Damla Etal; Anna Freeman; Ashley I. Heinson; Sonja Hess; Michael Huhn; Emily Hall; Alex Mackay; Jens Madsen; Christopher McCrae; Daniel Muthas; Steven Novick; Kristoffer Ostridge; Lisa Oberg; Adam Platt; Anthony D. Postle; C. Mirella Spalluto; Outi Vaarala; Junmin Wang; Karl J. Staples; Tom M. A. Wilkinson

doi:10.1183/23120541.00378-2022

Multiomics links global surfactant dysregulation with airflow obstruction and emphysema in COPD

Ventzislava A. Hristova, Alastair Watson, Raghothama Chaerkady, Matthew S. Glover, Jodie Ackland, Bastian Angerman, Graham Belfield, Maria G. Belvisi, Hannah Burke, Doriana Cellura, Howard W. Clark, Damla Etal, Anna Freeman, Ashley I. Heinson, Sonja Hess, Michael Huhn, Emily Hall, Alex Mackay, Jens Madsen, Christopher McCraeDaniel Muthas, Steven Novick, Kristoffer Ostridge, Lisa Oberg, Adam Platt, Anthony D. Postle, C. Mirella Spalluto, Outi Vaarala, Junmin Wang, Karl J. Staples, Tom M. A. Wilkinson

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Article number	00378-2022
Journal	ERJ Open Research
Volume	9
Issue number	3
Number of pages	17
ISSN	2312-0541
DOIs	https://doi.org/10.1183/23120541.00378-2022
Publication status	Published - 1 May 2023
MoE publication type	A1 Journal article-refereed

Fields of Science

3121 General medicine, internal medicine and other clinical medicine

Access to Document

10.1183/23120541.00378-2022

00378-2022.fullFinal published version, 1.09 MBLicence: CC BY-NC

Cite this

Hristova, V. A., Watson, A., Chaerkady, R., Glover, M. S., Ackland, J., Angerman, B., Belfield, G., Belvisi, M. G., Burke, H., Cellura, D., Clark, H. W., Etal, D., Freeman, A., Heinson, A. I., Hess, S., Huhn, M., Hall, E., Mackay, A., Madsen, J., ... Wilkinson, T. M. A. (2023). Multiomics links global surfactant dysregulation with airflow obstruction and emphysema in COPD. ERJ Open Research, 9(3), Article 00378-2022. https://doi.org/10.1183/23120541.00378-2022

@article{619785a757824e56806273ea65e778cd,

title = "Multiomics links global surfactant dysregulation with airflow obstruction and emphysema in COPD",

keywords = "Human sp-a, Pulmonary-disease, Protein-b, Serum-levels, Polymorphism, Expression, Proteomics, Tension, Marker, 3121 General medicine, internal medicine and other clinical medicine",

author = "Hristova, {Ventzislava A.} and Alastair Watson and Raghothama Chaerkady and Glover, {Matthew S.} and Jodie Ackland and Bastian Angerman and Graham Belfield and Belvisi, {Maria G.} and Hannah Burke and Doriana Cellura and Clark, {Howard W.} and Damla Etal and Anna Freeman and Heinson, {Ashley I.} and Sonja Hess and Michael Huhn and Emily Hall and Alex Mackay and Jens Madsen and Christopher McCrae and Daniel Muthas and Steven Novick and Kristoffer Ostridge and Lisa Oberg and Adam Platt and Postle, {Anthony D.} and Spalluto, {C. Mirella} and Outi Vaarala and Junmin Wang and Staples, {Karl J.} and Wilkinson, {Tom M. A.}",

year = "2023",

month = may,

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doi = "10.1183/23120541.00378-2022",

language = "English",

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Hristova, VA, Watson, A, Chaerkady, R, Glover, MS, Ackland, J, Angerman, B, Belfield, G, Belvisi, MG, Burke, H, Cellura, D, Clark, HW, Etal, D, Freeman, A, Heinson, AI, Hess, S, Huhn, M, Hall, E, Mackay, A, Madsen, J, McCrae, C, Muthas, D, Novick, S, Ostridge, K, Oberg, L, Platt, A, Postle, AD, Spalluto, CM, Vaarala, O, Wang, J, Staples, KJ & Wilkinson, TMA 2023, 'Multiomics links global surfactant dysregulation with airflow obstruction and emphysema in COPD', ERJ Open Research, vol. 9, no. 3, 00378-2022. https://doi.org/10.1183/23120541.00378-2022

TY - JOUR

T1 - Multiomics links global surfactant dysregulation with airflow obstruction and emphysema in COPD

AU - Hristova, Ventzislava A.

AU - Watson, Alastair

AU - Chaerkady, Raghothama

AU - Glover, Matthew S.

AU - Ackland, Jodie

AU - Angerman, Bastian

AU - Belfield, Graham

AU - Belvisi, Maria G.

AU - Burke, Hannah

AU - Cellura, Doriana

AU - Clark, Howard W.

AU - Etal, Damla

AU - Freeman, Anna

AU - Heinson, Ashley I.

AU - Hess, Sonja

AU - Huhn, Michael

AU - Hall, Emily

AU - Mackay, Alex

AU - Madsen, Jens

AU - McCrae, Christopher

AU - Muthas, Daniel

AU - Novick, Steven

AU - Ostridge, Kristoffer

AU - Oberg, Lisa

AU - Platt, Adam

AU - Postle, Anthony D.

AU - Spalluto, C. Mirella

AU - Vaarala, Outi

AU - Wang, Junmin

AU - Staples, Karl J.

AU - Wilkinson, Tom M. A.

PY - 2023/5/1

Y1 - 2023/5/1

KW - Human sp-a

KW - Pulmonary-disease

KW - Protein-b

KW - Serum-levels

KW - Polymorphism

KW - Expression

KW - Proteomics

KW - Tension

KW - Marker

KW - 3121 General medicine, internal medicine and other clinical medicine

U2 - 10.1183/23120541.00378-2022

DO - 10.1183/23120541.00378-2022

M3 - Article

C2 - 37228288

SN - 2312-0541

VL - 9

JO - ERJ Open Research

JF - ERJ Open Research

IS - 3

M1 - 00378-2022

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