Multiparametric platform for profiling lipid trafficking in human leukocytes

Simon G. Pfisterer; Ivonne Brock; Kristiina Kanerva; Iryna Hlushchenko; Lassi Paavolainen; Pietari Ripatti; Mohammad Majharul Islam; Aija Kyttälä; Maria D. Di Taranto; Annalisa Scotto di Frega; Giuliana Fortunato; Johanna Kuusisto; Peter Horvath; Samuli Ripatti; Markku Laakso; Elina Ikonen

doi:10.1016/j.crmeth.2022.100166

Multiparametric platform for profiling lipid trafficking in human leukocytes

Simon G. Pfisterer, Ivonne Brock, Kristiina Kanerva, Iryna Hlushchenko, Lassi Paavolainen, Pietari Ripatti, Mohammad Majharul Islam, Aija Kyttälä, Maria D. Di Taranto, Annalisa Scotto di Frega, Giuliana Fortunato, Johanna Kuusisto, Peter Horvath, Samuli Ripatti, Markku Laakso, Elina Ikonen

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Article number	100166
Journal	Cell Reports Methods
Volume	2
Issue number	2
Number of pages	17
ISSN	2667-2375
DOIs	https://doi.org/10.1016/j.crmeth.2022.100166
Publication status	Published - 2022
MoE publication type	A1 Journal article-refereed

Fields of Science

high-content imaging
automated image analysis
LDL
LDLR
lipid droplet
hypercholesterolemia
FH
obesity
LDL uptake
3111 Biomedicine
1182 Biochemistry, cell and molecular biology

Access to Document

10.1016/j.crmeth.2022.100166Licence: CC BY

1-s2.0-S2667237522000182-mainFinal published version, 2.63 MBLicence: CC BY

Cite this

Pfisterer, S. G., Brock, I., Kanerva, K., Hlushchenko, I., Paavolainen, L., Ripatti, P., Islam, M. M., Kyttälä, A., Di Taranto, M. D., Scotto di Frega, A., Fortunato, G., Kuusisto, J., Horvath, P., Ripatti, S., Laakso, M., & Ikonen, E. (2022). Multiparametric platform for profiling lipid trafficking in human leukocytes. Cell Reports Methods, 2(2), Article 100166. https://doi.org/10.1016/j.crmeth.2022.100166

@article{afb001a7f95a461e830a9fc5c4e9ac59,

title = "Multiparametric platform for profiling lipid trafficking in human leukocytes",

keywords = "high-content imaging, automated image analysis, LDL, LDLR, lipid droplet, hypercholesterolemia, FH, obesity, LDL uptake, 3111 Biomedicine, 1182 Biochemistry, cell and molecular biology",

author = "Pfisterer, \{Simon G.\} and Ivonne Brock and Kristiina Kanerva and Iryna Hlushchenko and Lassi Paavolainen and Pietari Ripatti and Islam, \{Mohammad Majharul\} and Aija Kytt{\"a}l{\"a} and \{Di Taranto\}, \{Maria D.\} and \{Scotto di Frega\}, Annalisa and Giuliana Fortunato and Johanna Kuusisto and Peter Horvath and Samuli Ripatti and Markku Laakso and Elina Ikonen",

year = "2022",

doi = "10.1016/j.crmeth.2022.100166",

language = "English",

volume = "2",

journal = "Cell Reports Methods",

issn = "2667-2375",

publisher = "Cell Press, Elsevier, Inc.",

number = "2",

}

Pfisterer, SG, Brock, I, Kanerva, K, Hlushchenko, I, Paavolainen, L, Ripatti, P, Islam, MM, Kyttälä, A, Di Taranto, MD, Scotto di Frega, A, Fortunato, G, Kuusisto, J, Horvath, P , Ripatti, S, Laakso, M & Ikonen, E 2022, 'Multiparametric platform for profiling lipid trafficking in human leukocytes', Cell Reports Methods, vol. 2, no. 2, 100166. https://doi.org/10.1016/j.crmeth.2022.100166

TY - JOUR

T1 - Multiparametric platform for profiling lipid trafficking in human leukocytes

AU - Pfisterer, Simon G.

AU - Brock, Ivonne

AU - Kanerva, Kristiina

AU - Hlushchenko, Iryna

AU - Paavolainen, Lassi

AU - Ripatti, Pietari

AU - Islam, Mohammad Majharul

AU - Kyttälä, Aija

AU - Di Taranto, Maria D.

AU - Scotto di Frega, Annalisa

AU - Fortunato, Giuliana

AU - Kuusisto, Johanna

AU - Horvath, Peter

AU - Ripatti, Samuli

AU - Laakso, Markku

AU - Ikonen, Elina

PY - 2022

Y1 - 2022

KW - high-content imaging

KW - automated image analysis

KW - LDL

KW - LDLR

KW - lipid droplet

KW - hypercholesterolemia

KW - FH

KW - obesity

KW - LDL uptake

KW - 3111 Biomedicine

KW - 1182 Biochemistry, cell and molecular biology

U2 - 10.1016/j.crmeth.2022.100166

DO - 10.1016/j.crmeth.2022.100166

M3 - Article

SN - 2667-2375

VL - 2

JO - Cell Reports Methods

JF - Cell Reports Methods

IS - 2

M1 - 100166

ER -