Murine cathepsin D deficiency is associated with dysmyelination/myelin disruption and accumulation of cholesteryl esters in the brain

Aino-Liisa Mutka, Aleksi Haapanen, Reijo Käkelä, Maria Lindfors, Ann K. Wright, Teija Inkinen, Martin Hermansson, Anne Rokka, Garry Corthals, Matti Jauhiainen, Thomas H. Gillingwater, Elina Ikonen, Jaana Tyynelä

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalJournal of Neurochemistry
Volume112
Issue number1
Pages (from-to)193-203
Number of pages11
ISSN0022-3042
DOIs
Publication statusPublished - 2010
MoE publication typeA1 Journal article-refereed

Fields of Science

  • cathepsin D
  • lipidomics
  • mouse model
  • myelin
  • proteomics
  • ultrastructure
  • NEURONAL-CEROID-LIPOFUSCINOSIS
  • IONIZATION MASS-SPECTROMETRY
  • CENTRAL-NERVOUS-SYSTEM
  • MYELIN BASIC-PROTEIN
  • APOLIPOPROTEIN-E
  • ALZHEIMERS-DISEASE
  • PLASMALOGEN DEFICIENCY
  • LYSOSOMAL STORAGE
  • IN-VIVO
  • MICE
  • 311 Basic medicine

Cite this

Mutka, Aino-Liisa ; Haapanen, Aleksi ; Käkelä, Reijo ; Lindfors, Maria ; Wright, Ann K. ; Inkinen, Teija ; Hermansson, Martin ; Rokka, Anne ; Corthals, Garry ; Jauhiainen, Matti ; Gillingwater, Thomas H. ; Ikonen, Elina ; Tyynelä, Jaana. / Murine cathepsin D deficiency is associated with dysmyelination/myelin disruption and accumulation of cholesteryl esters in the brain. In: Journal of Neurochemistry. 2010 ; Vol. 112, No. 1. pp. 193-203.
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title = "Murine cathepsin D deficiency is associated with dysmyelination/myelin disruption and accumulation of cholesteryl esters in the brain",
keywords = "cathepsin D, lipidomics, mouse model, myelin, proteomics, ultrastructure, NEURONAL-CEROID-LIPOFUSCINOSIS, IONIZATION MASS-SPECTROMETRY, CENTRAL-NERVOUS-SYSTEM, MYELIN BASIC-PROTEIN, APOLIPOPROTEIN-E, ALZHEIMERS-DISEASE, PLASMALOGEN DEFICIENCY, LYSOSOMAL STORAGE, IN-VIVO, MICE, 311 Basic medicine",
author = "Aino-Liisa Mutka and Aleksi Haapanen and Reijo K{\"a}kel{\"a} and Maria Lindfors and Wright, {Ann K.} and Teija Inkinen and Martin Hermansson and Anne Rokka and Garry Corthals and Matti Jauhiainen and Gillingwater, {Thomas H.} and Elina Ikonen and Jaana Tyynel{\"a}",
year = "2010",
doi = "10.1111/j.1471-4159.2009.06440.x",
language = "English",
volume = "112",
pages = "193--203",
journal = "Journal of Neurochemistry",
issn = "0022-3042",
publisher = "LIPPINCOTT-RAVEN PUBL",
number = "1",

}

Murine cathepsin D deficiency is associated with dysmyelination/myelin disruption and accumulation of cholesteryl esters in the brain. / Mutka, Aino-Liisa; Haapanen, Aleksi; Käkelä, Reijo; Lindfors, Maria; Wright, Ann K.; Inkinen, Teija; Hermansson, Martin; Rokka, Anne; Corthals, Garry; Jauhiainen, Matti; Gillingwater, Thomas H.; Ikonen, Elina; Tyynelä, Jaana.

In: Journal of Neurochemistry, Vol. 112, No. 1, 2010, p. 193-203.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Murine cathepsin D deficiency is associated with dysmyelination/myelin disruption and accumulation of cholesteryl esters in the brain

AU - Mutka, Aino-Liisa

AU - Haapanen, Aleksi

AU - Käkelä, Reijo

AU - Lindfors, Maria

AU - Wright, Ann K.

AU - Inkinen, Teija

AU - Hermansson, Martin

AU - Rokka, Anne

AU - Corthals, Garry

AU - Jauhiainen, Matti

AU - Gillingwater, Thomas H.

AU - Ikonen, Elina

AU - Tyynelä, Jaana

PY - 2010

Y1 - 2010

KW - cathepsin D

KW - lipidomics

KW - mouse model

KW - myelin

KW - proteomics

KW - ultrastructure

KW - NEURONAL-CEROID-LIPOFUSCINOSIS

KW - IONIZATION MASS-SPECTROMETRY

KW - CENTRAL-NERVOUS-SYSTEM

KW - MYELIN BASIC-PROTEIN

KW - APOLIPOPROTEIN-E

KW - ALZHEIMERS-DISEASE

KW - PLASMALOGEN DEFICIENCY

KW - LYSOSOMAL STORAGE

KW - IN-VIVO

KW - MICE

KW - 311 Basic medicine

U2 - 10.1111/j.1471-4159.2009.06440.x

DO - 10.1111/j.1471-4159.2009.06440.x

M3 - Article

VL - 112

SP - 193

EP - 203

JO - Journal of Neurochemistry

JF - Journal of Neurochemistry

SN - 0022-3042

IS - 1

ER -