Muscle and serum metabolomes are dysregulated in colon-26 tumor-bearing mice despite amelioration of cachexia with activin receptor type 2B ligand blockade

Juulia H. Lautaoja, Maciej Lalowski, Tuuli A. Nissinen, Jaakko Hentila, Yi Shi, Olli Ritvos, Sulin Cheng, Juha J. Hulmi

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalAmerican Journal of Physiology: Endocrinology and Metabolism
Volume316
Issue number5
Pages (from-to)E852-E865
Number of pages14
ISSN0193-1849
DOIs
Publication statusPublished - May 2019
MoE publication typeA1 Journal article-refereed

Fields of Science

  • cancer
  • C26
  • myostatin
  • phenylalanine
  • ribosome
  • FATTY-ACID OXIDATION
  • SKELETAL-MUSCLE
  • CANCER CACHEXIA
  • PROTEIN-SYNTHESIS
  • N-CARBAMYLGLUTAMATE
  • MURINE MODEL
  • MTOR
  • REVEALS
  • GLYCINE
  • MYOSTATIN
  • 1184 Genetics, developmental biology, physiology
  • 3122 Cancers

Cite this

@article{ff87241c66174999a7c5327f1a8f059a,
title = "Muscle and serum metabolomes are dysregulated in colon-26 tumor-bearing mice despite amelioration of cachexia with activin receptor type 2B ligand blockade",
keywords = "cancer, C26, myostatin, phenylalanine, ribosome, FATTY-ACID OXIDATION, SKELETAL-MUSCLE, CANCER CACHEXIA, PROTEIN-SYNTHESIS, N-CARBAMYLGLUTAMATE, MURINE MODEL, MTOR, REVEALS, GLYCINE, MYOSTATIN, 1184 Genetics, developmental biology, physiology, 3122 Cancers",
author = "Lautaoja, {Juulia H.} and Maciej Lalowski and Nissinen, {Tuuli A.} and Jaakko Hentila and Yi Shi and Olli Ritvos and Sulin Cheng and Hulmi, {Juha J.}",
year = "2019",
month = "5",
doi = "10.1152/ajpendo.00526.2018",
language = "English",
volume = "316",
pages = "E852--E865",
journal = "American Journal of Physiology: Endocrinology and Metabolism",
issn = "0193-1849",
publisher = "American Physiological Society",
number = "5",

}

Muscle and serum metabolomes are dysregulated in colon-26 tumor-bearing mice despite amelioration of cachexia with activin receptor type 2B ligand blockade. / Lautaoja, Juulia H.; Lalowski, Maciej; Nissinen, Tuuli A.; Hentila, Jaakko; Shi, Yi; Ritvos, Olli; Cheng, Sulin; Hulmi, Juha J.

In: American Journal of Physiology: Endocrinology and Metabolism, Vol. 316, No. 5, 05.2019, p. E852-E865.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Muscle and serum metabolomes are dysregulated in colon-26 tumor-bearing mice despite amelioration of cachexia with activin receptor type 2B ligand blockade

AU - Lautaoja, Juulia H.

AU - Lalowski, Maciej

AU - Nissinen, Tuuli A.

AU - Hentila, Jaakko

AU - Shi, Yi

AU - Ritvos, Olli

AU - Cheng, Sulin

AU - Hulmi, Juha J.

PY - 2019/5

Y1 - 2019/5

KW - cancer

KW - C26

KW - myostatin

KW - phenylalanine

KW - ribosome

KW - FATTY-ACID OXIDATION

KW - SKELETAL-MUSCLE

KW - CANCER CACHEXIA

KW - PROTEIN-SYNTHESIS

KW - N-CARBAMYLGLUTAMATE

KW - MURINE MODEL

KW - MTOR

KW - REVEALS

KW - GLYCINE

KW - MYOSTATIN

KW - 1184 Genetics, developmental biology, physiology

KW - 3122 Cancers

U2 - 10.1152/ajpendo.00526.2018

DO - 10.1152/ajpendo.00526.2018

M3 - Article

VL - 316

SP - E852-E865

JO - American Journal of Physiology: Endocrinology and Metabolism

JF - American Journal of Physiology: Endocrinology and Metabolism

SN - 0193-1849

IS - 5

ER -