Mutant p63 causes defective expansion of ectodermal progenitor cells and impaired FGF signalling in AEC syndrome

Giustina Ferone; Helen A. Thomason; Dario Antonini; Laura De Rosa; Bing Hu; Marica Gemei; Huiqing Zhou; Raffaele Ambrosio; David P. Rice; Dario Acampora; Hans van Bokhoven; Luigi Del Vecchio; Maranke I. Koster; Gianluca Tadini; Bradley Spencer-Dene; Michael Dixon; Jill Dixon; Caterina Missero

doi:10.1002/emmm.201100199

Mutant p63 causes defective expansion of ectodermal progenitor cells and impaired FGF signalling in AEC syndrome

Giustina Ferone, Helen A. Thomason, Dario Antonini, Laura De Rosa, Bing Hu, Marica Gemei, Huiqing Zhou, Raffaele Ambrosio, David P. Rice, Dario Acampora, Hans van Bokhoven, Luigi Del Vecchio, Maranke I. Koster, Gianluca Tadini, Bradley Spencer-Dene, Michael Dixon, Jill Dixon, Caterina Missero

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	EMBO molecular medicine
Volume	4
Issue number	3
Pages (from-to)	192-205
Number of pages	14
ISSN	1757-4676
DOIs	https://doi.org/10.1002/emmm.201100199
Publication status	Published - 2012
MoE publication type	A1 Journal article-refereed

Fields of Science

AEC syndrome
epidermis
FGF signalling
p63 knock-in
p63 target genes
GROWTH-FACTOR RECEPTOR
HAY-WELLS-SYNDROME
STEM-CELLS
EPIDERMAL MORPHOGENESIS
EPITHELIAL DEVELOPMENT
CRUCIAL ROLE
P53 HOMOLOG
ANKYLOBLEPHARON
HAIR
SKIN
313 Dentistry

Access to Document

10.1002/emmm.201100199

Mutant p63Final published version, 1.33 MBLicence: CC BY

Cite this

Ferone, G., Thomason, H. A., Antonini, D., De Rosa, L., Hu, B., Gemei, M., Zhou, H., Ambrosio, R., Rice, D. P., Acampora, D., van Bokhoven, H., Del Vecchio, L., Koster, M. I., Tadini, G., Spencer-Dene, B., Dixon, M., Dixon, J., & Missero, C. (2012). Mutant p63 causes defective expansion of ectodermal progenitor cells and impaired FGF signalling in AEC syndrome. EMBO molecular medicine, 4(3), 192-205. https://doi.org/10.1002/emmm.201100199

@article{00a296c2bf9142919063bb2730813fec,

title = "Mutant p63 causes defective expansion of ectodermal progenitor cells and impaired FGF signalling in AEC syndrome",

keywords = "AEC syndrome, epidermis, FGF signalling, p63 knock-in, p63 target genes, GROWTH-FACTOR RECEPTOR, HAY-WELLS-SYNDROME, STEM-CELLS, EPIDERMAL MORPHOGENESIS, EPITHELIAL DEVELOPMENT, CRUCIAL ROLE, P53 HOMOLOG, ANKYLOBLEPHARON, HAIR, SKIN, 313 Dentistry",

author = "Giustina Ferone and Thomason, {Helen A.} and Dario Antonini and {De Rosa}, Laura and Bing Hu and Marica Gemei and Huiqing Zhou and Raffaele Ambrosio and Rice, {David P.} and Dario Acampora and {van Bokhoven}, Hans and {Del Vecchio}, Luigi and Koster, {Maranke I.} and Gianluca Tadini and Bradley Spencer-Dene and Michael Dixon and Jill Dixon and Caterina Missero",

year = "2012",

doi = "10.1002/emmm.201100199",

language = "English",

volume = "4",

pages = "192--205",

journal = "EMBO molecular medicine",

issn = "1757-4676",

publisher = "Wiley",

number = "3",

}

Ferone, G, Thomason, HA, Antonini, D, De Rosa, L, Hu, B, Gemei, M, Zhou, H, Ambrosio, R, Rice, DP, Acampora, D, van Bokhoven, H, Del Vecchio, L, Koster, MI, Tadini, G, Spencer-Dene, B, Dixon, M, Dixon, J & Missero, C 2012, 'Mutant p63 causes defective expansion of ectodermal progenitor cells and impaired FGF signalling in AEC syndrome', EMBO molecular medicine, vol. 4, no. 3, pp. 192-205. https://doi.org/10.1002/emmm.201100199

TY - JOUR

T1 - Mutant p63 causes defective expansion of ectodermal progenitor cells and impaired FGF signalling in AEC syndrome

AU - Ferone, Giustina

AU - Thomason, Helen A.

AU - Antonini, Dario

AU - De Rosa, Laura

AU - Hu, Bing

AU - Gemei, Marica

AU - Zhou, Huiqing

AU - Ambrosio, Raffaele

AU - Rice, David P.

AU - Acampora, Dario

AU - van Bokhoven, Hans

AU - Del Vecchio, Luigi

AU - Koster, Maranke I.

AU - Tadini, Gianluca

AU - Spencer-Dene, Bradley

AU - Dixon, Michael

AU - Dixon, Jill

AU - Missero, Caterina

PY - 2012

Y1 - 2012

KW - AEC syndrome

KW - epidermis

KW - FGF signalling

KW - p63 knock-in

KW - p63 target genes

KW - GROWTH-FACTOR RECEPTOR

KW - HAY-WELLS-SYNDROME

KW - STEM-CELLS

KW - EPIDERMAL MORPHOGENESIS

KW - EPITHELIAL DEVELOPMENT

KW - CRUCIAL ROLE

KW - P53 HOMOLOG

KW - ANKYLOBLEPHARON

KW - HAIR

KW - SKIN

KW - 313 Dentistry

U2 - 10.1002/emmm.201100199

DO - 10.1002/emmm.201100199

M3 - Article

SN - 1757-4676

VL - 4

SP - 192

EP - 205

JO - EMBO molecular medicine

JF - EMBO molecular medicine

IS - 3

ER -