Myc antagonizes Ras-mediated growth arrest in leukemia cells through the inhibition of the Ras-ERK-p21(Cip1) pathway

J P  Vaque; J  Navascues; Y  Shiio; M  Laiho; N  Ajenjo; I  Mauleon; D  Matallanas; P  Crespo; J  Leon

doi:10.1074/jbc.M409503200

Myc antagonizes Ras-mediated growth arrest in leukemia cells through the inhibition of the Ras-ERK-p21(Cip1) pathway

J P Vaque, J Navascues, Y Shiio, M Laiho, N Ajenjo, I Mauleon, D Matallanas, P Crespo, J Leon

Research Programs Unit

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	Journal of Biological Chemistry
Volume	280
Pages (from-to)	1112-1122
Number of pages	11
ISSN	0021-9258
DOIs	https://doi.org/10.1074/jbc.M409503200
Publication status	Published - 2005
MoE publication type	A1 Journal article-refereed

Fields of Science

CHRONIC MYELOGENOUS LEUKEMIA
CHRONIC MYELOID-LEUKEMIA
MAP KINASE PATHWAYS
C-MYC
N-RAS
CYCLE ARREST
BLAST CRISIS
ENDOPLASMIC-RETICULUM
INDUCED PROLIFERATION
NEGATIVE REGULATION

Access to Document

10.1074/jbc.M409503200

Cite this

@article{41ab8a8ca5ff4f9d9cd20d6af72b69f6,

title = "Myc antagonizes Ras-mediated growth arrest in leukemia cells through the inhibition of the Ras-ERK-p21(Cip1) pathway",

keywords = "CHRONIC MYELOGENOUS LEUKEMIA, CHRONIC MYELOID-LEUKEMIA, MAP KINASE PATHWAYS, C-MYC, N-RAS, CYCLE ARREST, BLAST CRISIS, ENDOPLASMIC-RETICULUM, INDUCED PROLIFERATION, NEGATIVE REGULATION",

author = "Vaque, {J P} and J Navascues and Y Shiio and M Laiho and N Ajenjo and I Mauleon and D Matallanas and P Crespo and J Leon",

year = "2005",

doi = "10.1074/jbc.M409503200",

language = "English",

volume = "280",

pages = "1112--1122",

journal = "Journal of Biological Chemistry",

issn = "0021-9258",

publisher = "American Society for Biochemistry and Molecular Biology",

}

TY - JOUR

T1 - Myc antagonizes Ras-mediated growth arrest in leukemia cells through the inhibition of the Ras-ERK-p21(Cip1) pathway

AU - Vaque, J P

AU - Navascues, J

AU - Shiio, Y

AU - Laiho, M

AU - Ajenjo, N

AU - Mauleon, I

AU - Matallanas, D

AU - Crespo, P

AU - Leon, J

PY - 2005

Y1 - 2005

KW - CHRONIC MYELOGENOUS LEUKEMIA

KW - CHRONIC MYELOID-LEUKEMIA

KW - MAP KINASE PATHWAYS

KW - C-MYC

KW - N-RAS

KW - CYCLE ARREST

KW - BLAST CRISIS

KW - ENDOPLASMIC-RETICULUM

KW - INDUCED PROLIFERATION

KW - NEGATIVE REGULATION

U2 - 10.1074/jbc.M409503200

DO - 10.1074/jbc.M409503200

M3 - Article

SN - 0021-9258

VL - 280

SP - 1112

EP - 1122

JO - Journal of Biological Chemistry

JF - Journal of Biological Chemistry

ER -