Myc-induced AMPK-phospho p53 pathway activates Bak to sensitize mitochondrial apoptosis

Anni I. Nieminen, Vilja M. Eskelinen, Heidi M. Haikala, Topi A. Tervonen, Yan Yan, Johanna I. Partanen, Juha Klefström

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalProceedings of the National Academy of Sciences of the United States of America
Volume110
Issue number20
Pages (from-to)E1839-E1848
Number of pages10
ISSN0027-8424
DOIs
Publication statusPublished - 14 May 2013
MoE publication typeA1 Journal article-refereed

Fields of Science

  • oncogene
  • cell death
  • cancer metabolism
  • C-MYC
  • PROTEIN-KINASE
  • TUMOR SUPPRESSION
  • CELL-DEATH
  • IN-VIVO
  • MEMBRANE PERMEABILIZATION
  • ENERGETIC STRESS
  • GENE-EXPRESSION
  • BREAST-CANCER
  • BH3 DOMAINS
  • 3111 Biomedicine

Cite this

@article{dc382ab578b04b89bb14168a782d9e40,
title = "Myc-induced AMPK-phospho p53 pathway activates Bak to sensitize mitochondrial apoptosis",
keywords = "oncogene, cell death, cancer metabolism, C-MYC, PROTEIN-KINASE, TUMOR SUPPRESSION, CELL-DEATH, IN-VIVO, MEMBRANE PERMEABILIZATION, ENERGETIC STRESS, GENE-EXPRESSION, BREAST-CANCER, BH3 DOMAINS, 3111 Biomedicine",
author = "Nieminen, {Anni I.} and Eskelinen, {Vilja M.} and Haikala, {Heidi M.} and Tervonen, {Topi A.} and Yan Yan and Partanen, {Johanna I.} and Juha Klefstr{\"o}m",
year = "2013",
month = "5",
day = "14",
doi = "10.1073/pnas.1208530110",
language = "English",
volume = "110",
pages = "E1839--E1848",
journal = "Proceedings of the National Academy of Sciences of the United States of America",
issn = "0027-8424",
publisher = "National Academy of Sciences",
number = "20",

}

Myc-induced AMPK-phospho p53 pathway activates Bak to sensitize mitochondrial apoptosis. / Nieminen, Anni I.; Eskelinen, Vilja M.; Haikala, Heidi M.; Tervonen, Topi A.; Yan, Yan; Partanen, Johanna I.; Klefström, Juha.

In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, No. 20, 14.05.2013, p. E1839-E1848.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Myc-induced AMPK-phospho p53 pathway activates Bak to sensitize mitochondrial apoptosis

AU - Nieminen, Anni I.

AU - Eskelinen, Vilja M.

AU - Haikala, Heidi M.

AU - Tervonen, Topi A.

AU - Yan, Yan

AU - Partanen, Johanna I.

AU - Klefström, Juha

PY - 2013/5/14

Y1 - 2013/5/14

KW - oncogene

KW - cell death

KW - cancer metabolism

KW - C-MYC

KW - PROTEIN-KINASE

KW - TUMOR SUPPRESSION

KW - CELL-DEATH

KW - IN-VIVO

KW - MEMBRANE PERMEABILIZATION

KW - ENERGETIC STRESS

KW - GENE-EXPRESSION

KW - BREAST-CANCER

KW - BH3 DOMAINS

KW - 3111 Biomedicine

U2 - 10.1073/pnas.1208530110

DO - 10.1073/pnas.1208530110

M3 - Article

VL - 110

SP - E1839-E1848

JO - Proceedings of the National Academy of Sciences of the United States of America

JF - Proceedings of the National Academy of Sciences of the United States of America

SN - 0027-8424

IS - 20

ER -