Nicotinamide riboside improves muscle mitochondrial biogenesis, satellite cell differentiation, and gut microbiota in a twin study

Helena A. K. Lapatto; Minna Kuusela; Aino Heikkinen; Maheswary Muniandy; Birgitta W. van der Kolk; Swetha Gopalakrishnan; Noora Pöllänen; Martin Sandvik; Mark S. Schmidt; Sini Heinonen; Sina Saari; Juho Kuula; Antti Hakkarainen; Janne Tampio; Tuure Saarinen; Marja-Riitta Taskinen; Nina Lundbom; Per-Henrik Groop; Marja Tiirola; Pekka Katajisto; Marko Lehtonen; Charles Brenner; Jaakko Kaprio; Satu Pekkala; Miina Ollikainen; Kirsi H. Pietiläinen; Eija Pirinen

doi:10.1126/sciadv.add5163

Nicotinamide riboside improves muscle mitochondrial biogenesis, satellite cell differentiation, and gut microbiota in a twin study

Helena A. K. Lapatto, Minna Kuusela, Aino Heikkinen, Maheswary Muniandy, Birgitta W. van der Kolk, Swetha Gopalakrishnan, Noora Pöllänen, Martin Sandvik, Mark S. Schmidt, Sini Heinonen, Sina Saari, Juho Kuula, Antti Hakkarainen, Janne Tampio, Tuure Saarinen, Marja-Riitta Taskinen, Nina Lundbom, Per-Henrik Groop, Marja Tiirola, Pekka KatajistoMarko Lehtonen, Charles Brenner, Jaakko Kaprio, Satu Pekkala, Miina Ollikainen, Kirsi H. Pietiläinen, Eija Pirinen

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Article number	eadd5163
Journal	Science Advances
Volume	9
Issue number	2
Number of pages	24
ISSN	2375-2548
DOIs	https://doi.org/10.1126/sciadv.add5163
Publication status	Published - 13 Jan 2023
MoE publication type	A1 Journal article-refereed

Fields of Science

3111 Biomedicine
11832 Microbiology and virology

Access to Document

10.1126/sciadv.add5163

sciadv.add5163Final published version, 5.39 MBLicence: CC BY

Cite this

Lapatto, H. A. K., Kuusela, M., Heikkinen, A., Muniandy, M., van der Kolk, B. W., Gopalakrishnan, S., Pöllänen, N., Sandvik, M., Schmidt, M. S., Heinonen, S., Saari, S., Kuula, J., Hakkarainen, A., Tampio, J., Saarinen, T., Taskinen, M.-R., Lundbom, N., Groop, P.-H., Tiirola, M., ... Pirinen, E. (2023). Nicotinamide riboside improves muscle mitochondrial biogenesis, satellite cell differentiation, and gut microbiota in a twin study. Science Advances, 9(2), Article eadd5163. https://doi.org/10.1126/sciadv.add5163

@article{714d22d2aa5a4407aee4456b3290c766,

title = "Nicotinamide riboside improves muscle mitochondrial biogenesis, satellite cell differentiation, and gut microbiota in a twin study",

keywords = "High-fat diet, Dna methylation, Skeletal-muscle, Adipose-tissue, Faecalibacterium-prausnitzii, Nad(+), Metabolism, Niacin, Liver, Supplementation, 3111 Biomedicine, 11832 Microbiology and virology",

author = "Lapatto, {Helena A. K.} and Minna Kuusela and Aino Heikkinen and Maheswary Muniandy and {van der Kolk}, {Birgitta W.} and Swetha Gopalakrishnan and Noora P{\"o}ll{\"a}nen and Martin Sandvik and Schmidt, {Mark S.} and Sini Heinonen and Sina Saari and Juho Kuula and Antti Hakkarainen and Janne Tampio and Tuure Saarinen and Marja-Riitta Taskinen and Nina Lundbom and Per-Henrik Groop and Marja Tiirola and Pekka Katajisto and Marko Lehtonen and Charles Brenner and Jaakko Kaprio and Satu Pekkala and Miina Ollikainen and Pietil{\"a}inen, {Kirsi H.} and Eija Pirinen",

year = "2023",

month = jan,

day = "13",

doi = "10.1126/sciadv.add5163",

language = "English",

volume = "9",

journal = "Science Advances",

issn = "2375-2548",

publisher = "American Association for the Advancement of Science (AAAS)",

number = "2",

}

Lapatto, HAK, Kuusela, M, Heikkinen, A , Muniandy, M, van der Kolk, BW, Gopalakrishnan, S , Pöllänen, N , Sandvik, M, Schmidt, MS, Heinonen, S, Saari, S , Kuula, J , Hakkarainen, A, Tampio, J, Saarinen, T , Taskinen, M-R , Lundbom, N , Groop, P-H, Tiirola, M, Katajisto, P, Lehtonen, M, Brenner, C, Kaprio, J, Pekkala, S, Ollikainen, M , Pietiläinen, KH & Pirinen, E 2023, 'Nicotinamide riboside improves muscle mitochondrial biogenesis, satellite cell differentiation, and gut microbiota in a twin study', Science Advances, vol. 9, no. 2, eadd5163. https://doi.org/10.1126/sciadv.add5163

TY - JOUR

T1 - Nicotinamide riboside improves muscle mitochondrial biogenesis, satellite cell differentiation, and gut microbiota in a twin study

AU - Lapatto, Helena A. K.

AU - Kuusela, Minna

AU - Heikkinen, Aino

AU - Muniandy, Maheswary

AU - van der Kolk, Birgitta W.

AU - Gopalakrishnan, Swetha

AU - Pöllänen, Noora

AU - Sandvik, Martin

AU - Schmidt, Mark S.

AU - Heinonen, Sini

AU - Saari, Sina

AU - Kuula, Juho

AU - Hakkarainen, Antti

AU - Tampio, Janne

AU - Saarinen, Tuure

AU - Taskinen, Marja-Riitta

AU - Lundbom, Nina

AU - Groop, Per-Henrik

AU - Tiirola, Marja

AU - Katajisto, Pekka

AU - Lehtonen, Marko

AU - Brenner, Charles

AU - Kaprio, Jaakko

AU - Pekkala, Satu

AU - Ollikainen, Miina

AU - Pietiläinen, Kirsi H.

AU - Pirinen, Eija

PY - 2023/1/13

Y1 - 2023/1/13

KW - High-fat diet

KW - Dna methylation

KW - Skeletal-muscle

KW - Adipose-tissue

KW - Faecalibacterium-prausnitzii

KW - Nad(+)

KW - Metabolism

KW - Niacin

KW - Liver

KW - Supplementation

KW - 3111 Biomedicine

KW - 11832 Microbiology and virology

U2 - 10.1126/sciadv.add5163

DO - 10.1126/sciadv.add5163

M3 - Article

C2 - 36638183

SN - 2375-2548

VL - 9

JO - Science Advances

JF - Science Advances

IS - 2

M1 - eadd5163

ER -