Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription

Riina Kaukonen, Anja Mai, Maria Georgiadou, Markku Saari, Nicola De Franceschi, Timo Betz, Harri Sihto, Sami Ventela, Laura Elo, Eija Jokitalo, Jukka Westermarck, Pirkko-Liisa Kellokumpu-Lehtinen, Heikki Joensuu, Reidar Grenman, Johanna Ivaska

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
Article number12237
JournalNature Communications
Volume7
Number of pages15
ISSN2041-1723
DOIs
Publication statusPublished - Aug 2016
MoE publication typeA1 Journal article-refereed

Fields of Science

  • HISTONE DEMETHYLASE JMJD1A
  • EXTRACELLULAR-MATRIX
  • MALIGNANT PHENOTYPE
  • GENE-EXPRESSION
  • HIPPO PATHWAY
  • IN-VIVO
  • MECHANOTRANSDUCTION
  • GROWTH
  • YAP
  • FIBROBLASTS
  • 1182 Biochemistry, cell and molecular biology

Cite this

Kaukonen, R., Mai, A., Georgiadou, M., Saari, M., De Franceschi, N., Betz, T., ... Ivaska, J. (2016). Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription. Nature Communications, 7, [12237]. https://doi.org/10.1038/ncomms12237
Kaukonen, Riina ; Mai, Anja ; Georgiadou, Maria ; Saari, Markku ; De Franceschi, Nicola ; Betz, Timo ; Sihto, Harri ; Ventela, Sami ; Elo, Laura ; Jokitalo, Eija ; Westermarck, Jukka ; Kellokumpu-Lehtinen, Pirkko-Liisa ; Joensuu, Heikki ; Grenman, Reidar ; Ivaska, Johanna. / Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription. In: Nature Communications. 2016 ; Vol. 7.
@article{69d12e461d08400ca12ad2919966eb92,
title = "Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription",
keywords = "HISTONE DEMETHYLASE JMJD1A, EXTRACELLULAR-MATRIX, MALIGNANT PHENOTYPE, GENE-EXPRESSION, HIPPO PATHWAY, IN-VIVO, MECHANOTRANSDUCTION, GROWTH, YAP, FIBROBLASTS, 1182 Biochemistry, cell and molecular biology",
author = "Riina Kaukonen and Anja Mai and Maria Georgiadou and Markku Saari and {De Franceschi}, Nicola and Timo Betz and Harri Sihto and Sami Ventela and Laura Elo and Eija Jokitalo and Jukka Westermarck and Pirkko-Liisa Kellokumpu-Lehtinen and Heikki Joensuu and Reidar Grenman and Johanna Ivaska",
year = "2016",
month = "8",
doi = "10.1038/ncomms12237",
language = "English",
volume = "7",
journal = "Nature Communications",
issn = "2041-1723",
publisher = "Nature Publishing Group",

}

Kaukonen, R, Mai, A, Georgiadou, M, Saari, M, De Franceschi, N, Betz, T, Sihto, H, Ventela, S, Elo, L, Jokitalo, E, Westermarck, J, Kellokumpu-Lehtinen, P-L, Joensuu, H, Grenman, R & Ivaska, J 2016, 'Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription' Nature Communications, vol. 7, 12237. https://doi.org/10.1038/ncomms12237

Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription. / Kaukonen, Riina; Mai, Anja; Georgiadou, Maria; Saari, Markku; De Franceschi, Nicola; Betz, Timo; Sihto, Harri; Ventela, Sami; Elo, Laura; Jokitalo, Eija; Westermarck, Jukka; Kellokumpu-Lehtinen, Pirkko-Liisa; Joensuu, Heikki; Grenman, Reidar; Ivaska, Johanna.

In: Nature Communications, Vol. 7, 12237, 08.2016.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription

AU - Kaukonen, Riina

AU - Mai, Anja

AU - Georgiadou, Maria

AU - Saari, Markku

AU - De Franceschi, Nicola

AU - Betz, Timo

AU - Sihto, Harri

AU - Ventela, Sami

AU - Elo, Laura

AU - Jokitalo, Eija

AU - Westermarck, Jukka

AU - Kellokumpu-Lehtinen, Pirkko-Liisa

AU - Joensuu, Heikki

AU - Grenman, Reidar

AU - Ivaska, Johanna

PY - 2016/8

Y1 - 2016/8

KW - HISTONE DEMETHYLASE JMJD1A

KW - EXTRACELLULAR-MATRIX

KW - MALIGNANT PHENOTYPE

KW - GENE-EXPRESSION

KW - HIPPO PATHWAY

KW - IN-VIVO

KW - MECHANOTRANSDUCTION

KW - GROWTH

KW - YAP

KW - FIBROBLASTS

KW - 1182 Biochemistry, cell and molecular biology

U2 - 10.1038/ncomms12237

DO - 10.1038/ncomms12237

M3 - Article

VL - 7

JO - Nature Communications

JF - Nature Communications

SN - 2041-1723

M1 - 12237

ER -