Novel biological strategies for treatment of wear particle-induced periprosthetic osteolysis of orthopaedic implants for joint replacement

S. B. Goodman, E. Gibon, J. Pajarinen, T. -H. Lin, M. Keeney, P. -G. Ren, C. Nich, Z. Yao, K. Egashira, F. Yang, Y. T. Konttinen

Research output: Contribution to journalReview Articlepeer-review

Original languageEnglish
Article number20130962
JournalJournal of the Royal Society Interface
Volume11
Issue number93
Number of pages12
ISSN1742-5689
DOIs
Publication statusPublished - 6 Apr 2014
MoE publication typeA2 Review article in a scientific journal

Fields of Science

  • wear particles
  • orthopaedic implants
  • inflammation
  • cell trafficking
  • macrophage polarization
  • NF-kappa B
  • NF-KAPPA-B
  • TOTAL HIP-REPLACEMENT
  • COLONY-STIMULATING FACTOR
  • NITRIC-OXIDE SYNTHASE
  • NECROSIS-FACTOR-ALPHA
  • CONTINUOUS INTRAMEDULLARY INFUSION
  • MESENCHYMAL STEM-CELLS
  • BONE-CEMENT PARTICLES
  • TOLL-LIKE RECEPTORS
  • CHALLENGE IN-VITRO
  • 3121 General medicine, internal medicine and other clinical medicine

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