NOVEL CELLULAR GLYCAN COMPOSITIONS

Jarmo Laine, Tero Satomaa, JAri Natunen, Annamari Heiskanen, Juhani Saarinen, Taina Jaatinen, Milla Mikkola (Aho), Suvi Natunen

Research output: PatentScientific

Abstract

The invention describes novel compositions of glycans, glycomes, from human embryonic stem cells, and especially novel subcompositions of the glycomes with specific monosaccharide compositions and glycan structures. The invention is further directed to methods for modifying the glycomes and analysis of the glycomes and the modified glycomes. Furthermore, the invention is directed to stem cells carrying the modified glycomes on their surfaces. The glycomes are preferably analysed by profiling methods able to detect reproducibly and quantitatively numerous individual glycan structures at the same time. The most preferred type of the profile is a mass spectrometric profile. The invention specifically revealed novel target structures and is especially directed to the development of reagents recognizing the structures.
Original languageEnglish
Publication Year3 Jan 2008
Publication statusPublished - 3 Jan 2008
MoE publication typeH1 Granted patent

Cite this

Laine, J., Satomaa, T., Natunen, JA., Heiskanen, A., Saarinen, J., Jaatinen, T., ... Natunen, S. (2008). IPC No. C12N 5/0735 . NOVEL CELLULAR GLYCAN COMPOSITIONS. (Patent No. PCT/FI2007/050405).
Laine, Jarmo (Author) ; Satomaa, Tero (Author) ; Natunen, JAri (Author) ; Heiskanen, Annamari (Author) ; Saarinen, Juhani (Author) ; Jaatinen, Taina (Author) ; Mikkola (Aho), Milla (Author) ; Natunen, Suvi (Author). / NOVEL CELLULAR GLYCAN COMPOSITIONS. IPC No.: C12N 5/0735 . Patent No.: PCT/FI2007/050405.
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title = "NOVEL CELLULAR GLYCAN COMPOSITIONS",
abstract = "The invention describes novel compositions of glycans, glycomes, from human embryonic stem cells, and especially novel subcompositions of the glycomes with specific monosaccharide compositions and glycan structures. The invention is further directed to methods for modifying the glycomes and analysis of the glycomes and the modified glycomes. Furthermore, the invention is directed to stem cells carrying the modified glycomes on their surfaces. The glycomes are preferably analysed by profiling methods able to detect reproducibly and quantitatively numerous individual glycan structures at the same time. The most preferred type of the profile is a mass spectrometric profile. The invention specifically revealed novel target structures and is especially directed to the development of reagents recognizing the structures.",
author = "Jarmo Laine and Tero Satomaa and JAri Natunen and Annamari Heiskanen and Juhani Saarinen and Taina Jaatinen and {Mikkola (Aho)}, Milla and Suvi Natunen",
year = "2008",
month = "1",
day = "3",
language = "English",
type = "Patent",
note = "PCT/FI2007/050405; C12N 5/0735",

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Laine, J, Satomaa, T, Natunen, JA, Heiskanen, A, Saarinen, J, Jaatinen, T, Mikkola (Aho), M & Natunen, S 2008, NOVEL CELLULAR GLYCAN COMPOSITIONS, Patent No. PCT/FI2007/050405, IPC No. C12N 5/0735 .

NOVEL CELLULAR GLYCAN COMPOSITIONS. / Laine, Jarmo; Satomaa, Tero; Natunen, JAri; Heiskanen, Annamari; Saarinen, Juhani; Jaatinen, Taina; Mikkola (Aho), Milla; Natunen, Suvi.

IPC No.: C12N 5/0735 . Patent No.: PCT/FI2007/050405.

Research output: PatentScientific

TY - PAT

T1 - NOVEL CELLULAR GLYCAN COMPOSITIONS

AU - Laine, Jarmo

AU - Satomaa, Tero

AU - Natunen, JAri

AU - Heiskanen, Annamari

AU - Saarinen, Juhani

AU - Jaatinen, Taina

AU - Mikkola (Aho), Milla

AU - Natunen, Suvi

PY - 2008/1/3

Y1 - 2008/1/3

N2 - The invention describes novel compositions of glycans, glycomes, from human embryonic stem cells, and especially novel subcompositions of the glycomes with specific monosaccharide compositions and glycan structures. The invention is further directed to methods for modifying the glycomes and analysis of the glycomes and the modified glycomes. Furthermore, the invention is directed to stem cells carrying the modified glycomes on their surfaces. The glycomes are preferably analysed by profiling methods able to detect reproducibly and quantitatively numerous individual glycan structures at the same time. The most preferred type of the profile is a mass spectrometric profile. The invention specifically revealed novel target structures and is especially directed to the development of reagents recognizing the structures.

AB - The invention describes novel compositions of glycans, glycomes, from human embryonic stem cells, and especially novel subcompositions of the glycomes with specific monosaccharide compositions and glycan structures. The invention is further directed to methods for modifying the glycomes and analysis of the glycomes and the modified glycomes. Furthermore, the invention is directed to stem cells carrying the modified glycomes on their surfaces. The glycomes are preferably analysed by profiling methods able to detect reproducibly and quantitatively numerous individual glycan structures at the same time. The most preferred type of the profile is a mass spectrometric profile. The invention specifically revealed novel target structures and is especially directed to the development of reagents recognizing the structures.

M3 - Patent

M1 - PCT/FI2007/050405

ER -

Laine J, Satomaa T, Natunen JA, Heiskanen A, Saarinen J, Jaatinen T et al. NOVEL CELLULAR GLYCAN COMPOSITIONS. C12N 5/0735 . 2008 Jan 3.