Oleanolic acid derivative alleviates cardiac fibrosis through inhibiting PTP1B activity and regulating AMPK/TGF-β/Smads pathway

An-Hui Wang; Hao-Yue Ma; Yan-Liang Yi; Su-Jie Zhu; Zhe-Wei Yu; Jie Zhu; Si Mei; Shamuha Bahetibike; You-Qun Lu; Li-Ting Huang; Ruo-Yao Yang; Rui-Wang; Su-Long Xiao; Rong Qi

doi:10.1016/j.ejphar.2023.176116

Oleanolic acid derivative alleviates cardiac fibrosis through inhibiting PTP1B activity and regulating AMPK/TGF-β/Smads pathway

An-Hui Wang, Hao-Yue Ma, Yan-Liang Yi, Su-Jie Zhu, Zhe-Wei Yu, Jie Zhu, Si Mei, Shamuha Bahetibike, You-Qun Lu, Li-Ting Huang, Ruo-Yao Yang, Rui-Wang, Su-Long Xiao, Rong Qi

Institute for Molecular Medicine Finland

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Article number	176116
Journal	European Journal of Pharmacology
Volume	960
Number of pages	16
ISSN	0014-2999
DOIs	https://doi.org/10.1016/j.ejphar.2023.176116
Publication status	Published - 5 Dec 2023
MoE publication type	A1 Journal article-refereed

Fields of Science

AMPK/TGF-beta/Smads pathway
Cardiac fibrosis
Oleanolic acid derivative
Ptp1b
317 Pharmacy

Access to Document

10.1016/j.ejphar.2023.176116

Cite this

Wang, A.-H., Ma, H.-Y., Yi, Y.-L., Zhu, S.-J., Yu, Z.-W., Zhu, J., Mei, S., Bahetibike, S., Lu, Y.-Q., Huang, L.-T., Yang, R.-Y., Rui-Wang, Xiao, S.-L., & Qi, R. (2023). Oleanolic acid derivative alleviates cardiac fibrosis through inhibiting PTP1B activity and regulating AMPK/TGF-β/Smads pathway. European Journal of Pharmacology, 960, Article 176116. https://doi.org/10.1016/j.ejphar.2023.176116

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title = "Oleanolic acid derivative alleviates cardiac fibrosis through inhibiting PTP1B activity and regulating AMPK/TGF-β/Smads pathway",

keywords = "AMPK/TGF-beta/Smads pathway, Cardiac fibrosis, Oleanolic acid derivative, Ptp1b, 317 Pharmacy",

author = "An-Hui Wang and Hao-Yue Ma and Yan-Liang Yi and Su-Jie Zhu and Zhe-Wei Yu and Jie Zhu and Si Mei and Shamuha Bahetibike and You-Qun Lu and Li-Ting Huang and Ruo-Yao Yang and Rui-Wang and Su-Long Xiao and Rong Qi",

year = "2023",

month = dec,

day = "5",

doi = "10.1016/j.ejphar.2023.176116",

language = "English",

volume = "960",

journal = "European Journal of Pharmacology",

issn = "0014-2999",

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Wang, A-H, Ma, H-Y, Yi, Y-L, Zhu, S-J, Yu, Z-W, Zhu, J, Mei, S, Bahetibike, S, Lu, Y-Q, Huang, L-T, Yang, R-Y, Rui-Wang, Xiao, S-L & Qi, R 2023, 'Oleanolic acid derivative alleviates cardiac fibrosis through inhibiting PTP1B activity and regulating AMPK/TGF-β/Smads pathway', European Journal of Pharmacology, vol. 960, 176116. https://doi.org/10.1016/j.ejphar.2023.176116

TY - JOUR

T1 - Oleanolic acid derivative alleviates cardiac fibrosis through inhibiting PTP1B activity and regulating AMPK/TGF-β/Smads pathway

AU - Wang, An-Hui

AU - Ma, Hao-Yue

AU - Yi, Yan-Liang

AU - Zhu, Su-Jie

AU - Yu, Zhe-Wei

AU - Zhu, Jie

AU - Mei, Si

AU - Bahetibike, Shamuha

AU - Lu, You-Qun

AU - Huang, Li-Ting

AU - Yang, Ruo-Yao

AU - Rui-Wang,

AU - Xiao, Su-Long

AU - Qi, Rong

PY - 2023/12/5

Y1 - 2023/12/5

KW - AMPK/TGF-beta/Smads pathway

KW - Cardiac fibrosis

KW - Oleanolic acid derivative

KW - Ptp1b

KW - 317 Pharmacy

U2 - 10.1016/j.ejphar.2023.176116

DO - 10.1016/j.ejphar.2023.176116

M3 - Article

C2 - 38059443

SN - 0014-2999

VL - 960

JO - European Journal of Pharmacology

JF - European Journal of Pharmacology

M1 - 176116

ER -