Oncolytic adenovirus shapes the ovarian tumor microenvironment for potent tumor-infiltrating lymphocyte tumor reactivity

João Manuel Santos; Camilla Heiniö; Victor Cervera-Carrascon; Dafne C A Quixabeira; Mikko Siurala; Riikka Havunen; Ralf Butzow; Sadia Zafar; Tanja de Gruijl; Heini Lassus; Anna Kanerva; Akseli Hemminki

doi:10.1136/jitc-2019-000188

Oncolytic adenovirus shapes the ovarian tumor microenvironment for potent tumor-infiltrating lymphocyte tumor reactivity

João Manuel Santos, Camilla Heiniö, Victor Cervera-Carrascon, Dafne C A Quixabeira, Mikko Siurala, Riikka Havunen, Ralf Butzow, Sadia Zafar, Tanja de Gruijl, Heini Lassus, Anna Kanerva, Akseli Hemminki

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Article number	000188
Journal	Journal for Immunotherapy of Cancer
Volume	8
Issue number	1
Number of pages	15
ISSN	2051-1426
DOIs	https://doi.org/10.1136/jitc-2019-000188
Publication status	Published - Jan 2020
MoE publication type	A1 Journal article-refereed

Fields of Science

3111 Biomedicine
TIL therapy
adenovirus
immunotherapy
oncolytic virus
tumor microenvironment
tumor-infiltrating lymphocytes
CANCER-CELLS
IMMUNE-RESPONSE
PD-L1 EXPRESSION
NECROSIS-FACTOR-ALPHA
ADOPTIVE CELL THERAPY
METASTATIC MELANOMA
FAVORABLE PROGNOSIS
IN-VIVO
REGULATORY T-CELLS
COMPLETE RESPONSES

Access to Document

10.1136/jitc-2019-000188

e000188.fullFinal published version, 2.22 MBLicence: CC BY-NC

Cite this

Santos, J. M., Heiniö, C., Cervera-Carrascon, V., Quixabeira, D. C. A., Siurala, M., Havunen, R., Butzow, R., Zafar, S., de Gruijl, T., Lassus, H., Kanerva, A., & Hemminki, A. (2020). Oncolytic adenovirus shapes the ovarian tumor microenvironment for potent tumor-infiltrating lymphocyte tumor reactivity. Journal for Immunotherapy of Cancer, 8(1), [000188]. https://doi.org/10.1136/jitc-2019-000188

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title = "Oncolytic adenovirus shapes the ovarian tumor microenvironment for potent tumor-infiltrating lymphocyte tumor reactivity",

keywords = "3111 Biomedicine, TIL therapy, adenovirus, immunotherapy, oncolytic virus, tumor microenvironment, tumor-infiltrating lymphocytes, CANCER-CELLS, IMMUNE-RESPONSE, PD-L1 EXPRESSION, NECROSIS-FACTOR-ALPHA, ADOPTIVE CELL THERAPY, METASTATIC MELANOMA, FAVORABLE PROGNOSIS, IN-VIVO, REGULATORY T-CELLS, COMPLETE RESPONSES",

author = "Santos, {Jo{\~a}o Manuel} and Camilla Heini{\"o} and Victor Cervera-Carrascon and Quixabeira, {Dafne C A} and Mikko Siurala and Riikka Havunen and Ralf Butzow and Sadia Zafar and {de Gruijl}, Tanja and Heini Lassus and Anna Kanerva and Akseli Hemminki",

year = "2020",

month = jan,

doi = "10.1136/jitc-2019-000188",

language = "English",

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journal = "Journal for Immunotherapy of Cancer",

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publisher = "BioMed Central",

number = "1",

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Santos, JM, Heiniö, C, Cervera-Carrascon, V, Quixabeira, DCA, Siurala, M, Havunen, R, Butzow, R , Zafar, S, de Gruijl, T, Lassus, H, Kanerva, A & Hemminki, A 2020, 'Oncolytic adenovirus shapes the ovarian tumor microenvironment for potent tumor-infiltrating lymphocyte tumor reactivity', Journal for Immunotherapy of Cancer, vol. 8, no. 1, 000188. https://doi.org/10.1136/jitc-2019-000188

TY - JOUR

T1 - Oncolytic adenovirus shapes the ovarian tumor microenvironment for potent tumor-infiltrating lymphocyte tumor reactivity

AU - Santos, João Manuel

AU - Heiniö, Camilla

AU - Cervera-Carrascon, Victor

AU - Quixabeira, Dafne C A

AU - Siurala, Mikko

AU - Havunen, Riikka

AU - Butzow, Ralf

AU - Zafar, Sadia

AU - de Gruijl, Tanja

AU - Lassus, Heini

AU - Kanerva, Anna

AU - Hemminki, Akseli

PY - 2020/1

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KW - 3111 Biomedicine

KW - TIL therapy

KW - adenovirus

KW - immunotherapy

KW - oncolytic virus

KW - tumor microenvironment

KW - tumor-infiltrating lymphocytes

KW - CANCER-CELLS

KW - IMMUNE-RESPONSE

KW - PD-L1 EXPRESSION

KW - NECROSIS-FACTOR-ALPHA

KW - ADOPTIVE CELL THERAPY

KW - METASTATIC MELANOMA

KW - FAVORABLE PROGNOSIS

KW - IN-VIVO

KW - REGULATORY T-CELLS

KW - COMPLETE RESPONSES

U2 - 10.1136/jitc-2019-000188

DO - 10.1136/jitc-2019-000188

M3 - Article

VL - 8

JO - Journal for Immunotherapy of Cancer

JF - Journal for Immunotherapy of Cancer

SN - 2051-1426

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