ORP4L Extracts and Presents PIP2 from Plasma Membrane for PLC beta 3 Catalysis: Targeting It Eradicates Leukemia Stem Cells

Wenbin Zhong, Mengyang Xu, Chanjuan Li, Biying Zhu, Xiuye Cao, Dan Li, Huanzhao Chen, Chunxiu Hu, Rong Li, Chengwei Luo, Guoping Pan, Wenqiang Zhang, Chaofeng Lai, Tong Wang, Xin Du, Hong Chen, Guowang Xu, Vesa M. Olkkonen, Pingsheng Lei, Jun Xu & 1 others Daoguang Yan

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalCell Reports
Volume26
Issue number8
Pages (from-to)2166-+
Number of pages21
ISSN2211-1247
DOIs
Publication statusPublished - 19 Feb 2019
MoE publication typeA1 Journal article-refereed

Fields of Science

  • MOLECULAR-DYNAMICS SIMULATIONS
  • ACUTE MYELOID-LEUKEMIA
  • BINDING PROTEIN
  • CANCER
  • AMBER
  • ACTIVATION
  • TRANSPORT
  • HALLMARKS
  • OSW-1
  • 3111 Biomedicine
  • 1182 Biochemistry, cell and molecular biology

Cite this

Zhong, Wenbin ; Xu, Mengyang ; Li, Chanjuan ; Zhu, Biying ; Cao, Xiuye ; Li, Dan ; Chen, Huanzhao ; Hu, Chunxiu ; Li, Rong ; Luo, Chengwei ; Pan, Guoping ; Zhang, Wenqiang ; Lai, Chaofeng ; Wang, Tong ; Du, Xin ; Chen, Hong ; Xu, Guowang ; Olkkonen, Vesa M. ; Lei, Pingsheng ; Xu, Jun ; Yan, Daoguang. / ORP4L Extracts and Presents PIP2 from Plasma Membrane for PLC beta 3 Catalysis : Targeting It Eradicates Leukemia Stem Cells. In: Cell Reports. 2019 ; Vol. 26, No. 8. pp. 2166-+.
@article{7baff0eec0d343399505cf8479ca8c6a,
title = "ORP4L Extracts and Presents PIP2 from Plasma Membrane for PLC beta 3 Catalysis: Targeting It Eradicates Leukemia Stem Cells",
keywords = "MOLECULAR-DYNAMICS SIMULATIONS, ACUTE MYELOID-LEUKEMIA, BINDING PROTEIN, CANCER, AMBER, ACTIVATION, TRANSPORT, HALLMARKS, OSW-1, 3111 Biomedicine, 1182 Biochemistry, cell and molecular biology",
author = "Wenbin Zhong and Mengyang Xu and Chanjuan Li and Biying Zhu and Xiuye Cao and Dan Li and Huanzhao Chen and Chunxiu Hu and Rong Li and Chengwei Luo and Guoping Pan and Wenqiang Zhang and Chaofeng Lai and Tong Wang and Xin Du and Hong Chen and Guowang Xu and Olkkonen, {Vesa M.} and Pingsheng Lei and Jun Xu and Daoguang Yan",
year = "2019",
month = "2",
day = "19",
doi = "10.1016/j.celrep.2019.01.082",
language = "English",
volume = "26",
pages = "2166--+",
journal = "Cell Reports",
issn = "2211-1247",
publisher = "Cell Press",
number = "8",

}

Zhong, W, Xu, M, Li, C, Zhu, B, Cao, X, Li, D, Chen, H, Hu, C, Li, R, Luo, C, Pan, G, Zhang, W, Lai, C, Wang, T, Du, X, Chen, H, Xu, G, Olkkonen, VM, Lei, P, Xu, J & Yan, D 2019, 'ORP4L Extracts and Presents PIP2 from Plasma Membrane for PLC beta 3 Catalysis: Targeting It Eradicates Leukemia Stem Cells' Cell Reports, vol. 26, no. 8, pp. 2166-+. https://doi.org/10.1016/j.celrep.2019.01.082

ORP4L Extracts and Presents PIP2 from Plasma Membrane for PLC beta 3 Catalysis : Targeting It Eradicates Leukemia Stem Cells. / Zhong, Wenbin; Xu, Mengyang; Li, Chanjuan; Zhu, Biying; Cao, Xiuye; Li, Dan; Chen, Huanzhao; Hu, Chunxiu; Li, Rong; Luo, Chengwei; Pan, Guoping; Zhang, Wenqiang; Lai, Chaofeng; Wang, Tong; Du, Xin; Chen, Hong; Xu, Guowang; Olkkonen, Vesa M.; Lei, Pingsheng; Xu, Jun; Yan, Daoguang.

In: Cell Reports, Vol. 26, No. 8, 19.02.2019, p. 2166-+.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - ORP4L Extracts and Presents PIP2 from Plasma Membrane for PLC beta 3 Catalysis

T2 - Targeting It Eradicates Leukemia Stem Cells

AU - Zhong, Wenbin

AU - Xu, Mengyang

AU - Li, Chanjuan

AU - Zhu, Biying

AU - Cao, Xiuye

AU - Li, Dan

AU - Chen, Huanzhao

AU - Hu, Chunxiu

AU - Li, Rong

AU - Luo, Chengwei

AU - Pan, Guoping

AU - Zhang, Wenqiang

AU - Lai, Chaofeng

AU - Wang, Tong

AU - Du, Xin

AU - Chen, Hong

AU - Xu, Guowang

AU - Olkkonen, Vesa M.

AU - Lei, Pingsheng

AU - Xu, Jun

AU - Yan, Daoguang

PY - 2019/2/19

Y1 - 2019/2/19

KW - MOLECULAR-DYNAMICS SIMULATIONS

KW - ACUTE MYELOID-LEUKEMIA

KW - BINDING PROTEIN

KW - CANCER

KW - AMBER

KW - ACTIVATION

KW - TRANSPORT

KW - HALLMARKS

KW - OSW-1

KW - 3111 Biomedicine

KW - 1182 Biochemistry, cell and molecular biology

U2 - 10.1016/j.celrep.2019.01.082

DO - 10.1016/j.celrep.2019.01.082

M3 - Article

VL - 26

SP - 2166-+

JO - Cell Reports

JF - Cell Reports

SN - 2211-1247

IS - 8

ER -