Oversized ubiquinones as molecular probes for structural dynamics of the ubiquinone reaction site in mitochondrial respiratory complex I

Shinpei Uno, Takahiro Masuya, Kyoko Shinzawa-Itoh, Jonathan Lasham, Outi Haapanen, Tomoo Shiba, Daniel Ken Inaoka, Vivek Sharma, Masatoshi Murai, Hideto Miyoshi

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalJournal of Biological Chemistry
Volume295
Issue number8
Pages (from-to)2449-2463
Number of pages15
ISSN0021-9258
DOIs
Publication statusPublished - 21 Feb 2020
MoE publication typeA1 Journal article-refereed

Fields of Science

  • bioenergetics
  • mitochondria
  • complex I
  • ubiquinone
  • chemical biology
  • respiratory chain
  • proton pump
  • PINPOINT CHEMICAL-MODIFICATION
  • 49 KDA
  • CRYSTAL-STRUCTURE
  • INNER MEMBRANE
  • PROTON PUMP
  • NADH
  • REDUCTION
  • OXIDOREDUCTASE
  • MECHANISM
  • BINDING
  • 1182 Biochemistry, cell and molecular biology
  • 114 Physical sciences

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