Palmitoyl protein thioesterase 1 (Ppt1)-deficient mouse neurons show alterations in cholesterol metabolism and calcium homeostasis prior to synaptic dysfunction

Laura Ahtiainen, Julia Kolikova, Aino-Liisa Mutka, Kaisu Luiro, Massimiliano Gentile, Elina Ikonen, Leonard Khiroug, Anu Jalanko, Outi Kopra

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalNeurobiology of Disease
Volume28
Pages (from-to)52-64
Number of pages13
ISSN0969-9961
DOIs
Publication statusPublished - 2007
MoE publication typeA1 Journal article-refereed

Fields of Science

  • palmitoyl protein thioesterase 1
  • infantile neuronal ceroid lipofuscinosis
  • neuron culture
  • synapse
  • neuron maturation
  • calcium homeostasis
  • cholesterol
  • microarray
  • CEROID-LIPOFUSCINOSIS
  • ALPHA-SYNUCLEIN
  • ALZHEIMERS-DISEASE
  • GLIAL ACTIVATION
  • BATTEN-DISEASE
  • GENE ONTOLOGY
  • KNOCKOUT MICE
  • BRAIN-SLICES
  • INFANTILE
  • NEURODEGENERATION
  • 118 Biological sciences
  • 311 Basic medicine
  • 515 Psychology

Cite this

@article{29a77229a0374f1d9cf81b66962e4b73,
title = "Palmitoyl protein thioesterase 1 (Ppt1)-deficient mouse neurons show alterations in cholesterol metabolism and calcium homeostasis prior to synaptic dysfunction",
keywords = "palmitoyl protein thioesterase 1, infantile neuronal ceroid lipofuscinosis, neuron culture, synapse, neuron maturation, calcium homeostasis, cholesterol, microarray, CEROID-LIPOFUSCINOSIS, ALPHA-SYNUCLEIN, ALZHEIMERS-DISEASE, GLIAL ACTIVATION, BATTEN-DISEASE, GENE ONTOLOGY, KNOCKOUT MICE, BRAIN-SLICES, INFANTILE, NEURODEGENERATION, 118 Biological sciences, 311 Basic medicine, 515 Psychology",
author = "Laura Ahtiainen and Julia Kolikova and Aino-Liisa Mutka and Kaisu Luiro and Massimiliano Gentile and Elina Ikonen and Leonard Khiroug and Anu Jalanko and Outi Kopra",
year = "2007",
doi = "10.1016/j.nbd.2007.06.012",
language = "English",
volume = "28",
pages = "52--64",
journal = "Neurobiology of Disease",
issn = "0969-9961",
publisher = "ACADEMIC PRESS INC ELSEVIER SCIENCE",

}

Palmitoyl protein thioesterase 1 (Ppt1)-deficient mouse neurons show alterations in cholesterol metabolism and calcium homeostasis prior to synaptic dysfunction. / Ahtiainen, Laura; Kolikova, Julia; Mutka, Aino-Liisa; Luiro, Kaisu; Gentile, Massimiliano; Ikonen, Elina; Khiroug, Leonard; Jalanko, Anu; Kopra, Outi.

In: Neurobiology of Disease, Vol. 28, 2007, p. 52-64.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Palmitoyl protein thioesterase 1 (Ppt1)-deficient mouse neurons show alterations in cholesterol metabolism and calcium homeostasis prior to synaptic dysfunction

AU - Ahtiainen, Laura

AU - Kolikova, Julia

AU - Mutka, Aino-Liisa

AU - Luiro, Kaisu

AU - Gentile, Massimiliano

AU - Ikonen, Elina

AU - Khiroug, Leonard

AU - Jalanko, Anu

AU - Kopra, Outi

PY - 2007

Y1 - 2007

KW - palmitoyl protein thioesterase 1

KW - infantile neuronal ceroid lipofuscinosis

KW - neuron culture

KW - synapse

KW - neuron maturation

KW - calcium homeostasis

KW - cholesterol

KW - microarray

KW - CEROID-LIPOFUSCINOSIS

KW - ALPHA-SYNUCLEIN

KW - ALZHEIMERS-DISEASE

KW - GLIAL ACTIVATION

KW - BATTEN-DISEASE

KW - GENE ONTOLOGY

KW - KNOCKOUT MICE

KW - BRAIN-SLICES

KW - INFANTILE

KW - NEURODEGENERATION

KW - 118 Biological sciences

KW - 311 Basic medicine

KW - 515 Psychology

U2 - 10.1016/j.nbd.2007.06.012

DO - 10.1016/j.nbd.2007.06.012

M3 - Article

VL - 28

SP - 52

EP - 64

JO - Neurobiology of Disease

JF - Neurobiology of Disease

SN - 0969-9961

ER -