Personal model-assisted identification of NAD(+) and glutathione metabolism as intervention target in NAFLD

Adil Mardinoglu, Elias Bjornson, Cheng Zhang, Martina Klevstig, Sanni Söderlund, Marcus Ståhlman, Martin Adiels, Antti Hakkarainen, Nina Lundbom, Murat Kilicarslan, Björn M. Hallström, Jesper Lundbom, Bruno Verges, Peter Hugh R. Barrett, Gerald F. Watts, Mireille J. Serlie, Jens Nielsen, Mathias Uhlen, Ulf Smith, Hanns-Ulrich MarschallMarja-Riitta Taskinen, Jan Boren

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
Article number916
JournalMolecular Systems Biology
Volume13
Issue number3
Number of pages17
ISSN1744-4292
DOIs
Publication statusPublished - Mar 2017
MoE publication typeA1 Journal article-refereed

Fields of Science

  • glutathione
  • NAFLD
  • personalized genome-scale metabolic modeling
  • serine
  • FATTY LIVER-DISEASE
  • AMINO-ACID-METABOLISM
  • TISSUE BLOOD-FLOW
  • ADIPOSE-TISSUE
  • GENOME-SCALE
  • INSULIN-RESISTANCE
  • HEPATOCELLULAR-CARCINOMA
  • DRUG TARGETS
  • OBESITY
  • MUSCLE
  • 3111 Biomedicine
  • 1182 Biochemistry, cell and molecular biology

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