PGC-1 alpha Signaling Increases GABA(A) Receptor Subunit alpha 2 Expression, GABAergic Neurotransmission and Anxiety-Like Behavior in Mice

Taavi Vanaveski; Svetlana Molchanova; null Dan Duc Pham; Annika Schäfer; Ceren Pajanoja; Jane Narvik; Vignesh Srinivasan; Mari Urb; Maria Koivisto; Eero Vasar; Tonis Timmusk; Rimante Minkeviciene; Ove Eriksson; Maciej Lalowski; Tomi Taira; Laura Korhonen; Vootele Voikar; Dan Lindholm

doi:10.3389/fnmol.2021.588230

PGC-1 alpha Signaling Increases GABA(A) Receptor Subunit alpha 2 Expression, GABAergic Neurotransmission and Anxiety-Like Behavior in Mice

Taavi Vanaveski, Svetlana Molchanova, Dan Duc Pham, Annika Schäfer, Ceren Pajanoja, Jane Narvik, Vignesh Srinivasan, Mari Urb, Maria Koivisto, Eero Vasar, Tonis Timmusk, Rimante Minkeviciene, Ove Eriksson, Maciej Lalowski, Tomi Taira, Laura Korhonen, Vootele Voikar, Dan Lindholm

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Article number	588230
Journal	Frontiers in Molecular Neuroscience
Volume	14
Number of pages	16
ISSN	1662-5099
DOIs	https://doi.org/10.3389/fnmol.2021.588230
Publication status	Published - 1 Feb 2021
MoE publication type	A1 Journal article-refereed

Fields of Science

GABA-A receptors
PGC-1&#945
PPAR&#947
pioglitazone
gene expression
neurotransmission
anxiety
behavioral test
3112 Neurosciences

Access to Document

10.3389/fnmol.2021.588230

fnmol-14-588230Final published version, 3.22 MBLicence: CC BY

Cite this

Vanaveski, T., Molchanova, S., Dan Duc Pham, Schäfer, A., Pajanoja, C., Narvik, J., Srinivasan, V., Urb, M., Koivisto, M., Vasar, E., Timmusk, T., Minkeviciene, R., Eriksson, O., Lalowski, M., Taira, T., Korhonen, L., Voikar, V., & Lindholm, D. (2021). PGC-1 alpha Signaling Increases GABA(A) Receptor Subunit alpha 2 Expression, GABAergic Neurotransmission and Anxiety-Like Behavior in Mice. Frontiers in Molecular Neuroscience, 14, Article 588230. https://doi.org/10.3389/fnmol.2021.588230

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author = "Taavi Vanaveski and Svetlana Molchanova and {Dan Duc Pham} and Annika Sch{\"a}fer and Ceren Pajanoja and Jane Narvik and Vignesh Srinivasan and Mari Urb and Maria Koivisto and Eero Vasar and Tonis Timmusk and Rimante Minkeviciene and Ove Eriksson and Maciej Lalowski and Tomi Taira and Laura Korhonen and Vootele Voikar and Dan Lindholm",

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doi = "10.3389/fnmol.2021.588230",

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Vanaveski, T, Molchanova, S, Dan Duc Pham, , Schäfer, A , Pajanoja, C, Narvik, J, Srinivasan, V, Urb, M, Koivisto, M, Vasar, E, Timmusk, T, Minkeviciene, R, Eriksson, O , Lalowski, M , Taira, T, Korhonen, L, Voikar, V & Lindholm, D 2021, 'PGC-1 alpha Signaling Increases GABA(A) Receptor Subunit alpha 2 Expression, GABAergic Neurotransmission and Anxiety-Like Behavior in Mice', Frontiers in Molecular Neuroscience, vol. 14, 588230. https://doi.org/10.3389/fnmol.2021.588230

TY - JOUR

T1 - PGC-1 alpha Signaling Increases GABA(A) Receptor Subunit alpha 2 Expression, GABAergic Neurotransmission and Anxiety-Like Behavior in Mice

AU - Vanaveski, Taavi

AU - Molchanova, Svetlana

AU - Dan Duc Pham, null

AU - Schäfer, Annika

AU - Pajanoja, Ceren

AU - Narvik, Jane

AU - Srinivasan, Vignesh

AU - Urb, Mari

AU - Koivisto, Maria

AU - Vasar, Eero

AU - Timmusk, Tonis

AU - Minkeviciene, Rimante

AU - Eriksson, Ove

AU - Lalowski, Maciej

AU - Taira, Tomi

AU - Korhonen, Laura

AU - Voikar, Vootele

AU - Lindholm, Dan

PY - 2021/2/1

Y1 - 2021/2/1

KW - GABA-A receptors

KW - PGC-1&#945

KW - PPAR&#947

KW - pioglitazone

KW - gene expression

KW - neurotransmission

KW - anxiety

KW - behavioral test

KW - 3112 Neurosciences

U2 - 10.3389/fnmol.2021.588230

DO - 10.3389/fnmol.2021.588230

M3 - Article

SN - 1662-5099

VL - 14

JO - Frontiers in Molecular Neuroscience

JF - Frontiers in Molecular Neuroscience

M1 - 588230

ER -