Phenome-wide association studies across large population cohorts support drug target validation

23andMe Res Team

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
Article number4285
JournalNature Communications
Volume9
Number of pages13
ISSN2041-1723
DOIs
Publication statusPublished - 16 Oct 2018
MoE publication typeA1 Journal article-refereed

Fields of Science

  • SYSTEMIC-LUPUS-ERYTHEMATOSUS
  • INFLAMMATORY-BOWEL-DISEASE
  • ELECTRONIC HEALTH RECORDS
  • WHOLE-GENOME ASSOCIATION
  • CORONARY-ARTERY-DISEASE
  • FALSE DISCOVERY RATE
  • BODY-MASS INDEX
  • GENETIC INFLUENCES
  • LARGE-SCALE
  • RISK LOCI
  • 3111 Biomedicine
  • 3142 Public health care science, environmental and occupational health
  • 3121 Internal medicine

Cite this

@article{d46f5ef1be5a40d28d3d8da9ed496bf9,
title = "Phenome-wide association studies across large population cohorts support drug target validation",
keywords = "SYSTEMIC-LUPUS-ERYTHEMATOSUS, INFLAMMATORY-BOWEL-DISEASE, ELECTRONIC HEALTH RECORDS, WHOLE-GENOME ASSOCIATION, CORONARY-ARTERY-DISEASE, FALSE DISCOVERY RATE, BODY-MASS INDEX, GENETIC INFLUENCES, LARGE-SCALE, RISK LOCI, 3111 Biomedicine, 3142 Public health care science, environmental and occupational health, 3121 Internal medicine",
author = "{23andMe Res Team} and Dorothee Diogo and Chao Tian and Franklin, {Christopher S.} and Mervi Alanne-Kinnunen and Michael March and Spencer, {Chris C. A.} and Ciara Vangjeli and Weale, {Michael E.} and Hannele Mattsson and Elina Kilpel{\"a}inen and Sleiman, {Patrick M. A.} and Reilly, {Dermot F.} and Joshua McElwee and Maranville, {Joseph C.} and Chatterjee, {Arnaub K.} and Aman Bhandari and Nguyen, {Khanh-Dung H.} and Karol Estrada and Mary-Pat Reeve and Janna Hutz and Nan Bing and Sally John and MacArthur, {Daniel G.} and Veikko Salomaa and Samuli Ripatti and Hakon Hakonarson and Daly, {Mark J.} and Aarno Palotie and Hinds, {David A.} and Peter Donnelly and Fox, {Caroline S.} and Day-Williams, {Aaron G.} and Plenge, {Robert M.} and Heiko Runz",
year = "2018",
month = "10",
day = "16",
doi = "10.1038/s41467-018-06540-3",
language = "English",
volume = "9",
journal = "Nature Communications",
issn = "2041-1723",
publisher = "Nature Publishing Group",

}

Phenome-wide association studies across large population cohorts support drug target validation. / 23andMe Res Team.

In: Nature Communications, Vol. 9, 4285, 16.10.2018.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Phenome-wide association studies across large population cohorts support drug target validation

AU - 23andMe Res Team

AU - Diogo, Dorothee

AU - Tian, Chao

AU - Franklin, Christopher S.

AU - Alanne-Kinnunen, Mervi

AU - March, Michael

AU - Spencer, Chris C. A.

AU - Vangjeli, Ciara

AU - Weale, Michael E.

AU - Mattsson, Hannele

AU - Kilpeläinen, Elina

AU - Sleiman, Patrick M. A.

AU - Reilly, Dermot F.

AU - McElwee, Joshua

AU - Maranville, Joseph C.

AU - Chatterjee, Arnaub K.

AU - Bhandari, Aman

AU - Nguyen, Khanh-Dung H.

AU - Estrada, Karol

AU - Reeve, Mary-Pat

AU - Hutz, Janna

AU - Bing, Nan

AU - John, Sally

AU - MacArthur, Daniel G.

AU - Salomaa, Veikko

AU - Ripatti, Samuli

AU - Hakonarson, Hakon

AU - Daly, Mark J.

AU - Palotie, Aarno

AU - Hinds, David A.

AU - Donnelly, Peter

AU - Fox, Caroline S.

AU - Day-Williams, Aaron G.

AU - Plenge, Robert M.

AU - Runz, Heiko

PY - 2018/10/16

Y1 - 2018/10/16

KW - SYSTEMIC-LUPUS-ERYTHEMATOSUS

KW - INFLAMMATORY-BOWEL-DISEASE

KW - ELECTRONIC HEALTH RECORDS

KW - WHOLE-GENOME ASSOCIATION

KW - CORONARY-ARTERY-DISEASE

KW - FALSE DISCOVERY RATE

KW - BODY-MASS INDEX

KW - GENETIC INFLUENCES

KW - LARGE-SCALE

KW - RISK LOCI

KW - 3111 Biomedicine

KW - 3142 Public health care science, environmental and occupational health

KW - 3121 Internal medicine

U2 - 10.1038/s41467-018-06540-3

DO - 10.1038/s41467-018-06540-3

M3 - Article

VL - 9

JO - Nature Communications

JF - Nature Communications

SN - 2041-1723

M1 - 4285

ER -