Phosphorylation of PACSIN2 at S313 Regulates Podocyte Architecture in Coordination with N-WASP

Rim Bouslama; Vincent Dumont; Sonja Lindfors; Lassi Paavolainen; Jukka Tienari; Harry Nisen; Tuomas Mirtti; Moin A. Saleem; Daniel Gordin; Per Henrik Groop; Shiro Suetsugu; Sanna Lehtonen

doi:10.3390/cells12111487

Phosphorylation of PACSIN2 at S313 Regulates Podocyte Architecture in Coordination with N-WASP

Rim Bouslama, Vincent Dumont, Sonja Lindfors, Lassi Paavolainen, Jukka Tienari, Harry Nisen, Tuomas Mirtti, Moin A. Saleem, Daniel Gordin, Per Henrik Groop, Shiro Suetsugu, Sanna Lehtonen

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Article number	1487
Journal	Cells
Volume	12
Issue number	11
Number of pages	19
ISSN	2073-4409
DOIs	https://doi.org/10.3390/cells12111487
Publication status	Published - 27 May 2023
MoE publication type	A1 Journal article-refereed

Bibliographical note

Funding Information:
This work was supported by grants from the Doctoral Programme in Biomedicine (to RB) and Finnish Diabetes Research Foundation (Diabetestutkimussäätiö, to RB, VD and SoL), Finnish Kidney Foundation (Munuaissäätiö, to RB, VD and SoL), Onni and Hilja Tuovinen Foundation (to RB), Finnish-Norwegian Medical Research Foundation (to SoL), Jalmari and Rauha Ahokas Foundation (to RB and VD), Orion Foundation (to VD), Alfred Kordelin Foundation (to VD), Maud Kuistila Foundation (to VD), HiLife, University of Helsinki (to SaL, DG), Sigrid Jusélius Foundation (to SaL, DG), Päivikki and Sakari Sohlberg Foundation (to SoL, DG), Liv och Hälsa Society (to DG), Medical Society of Finland (Finska Läkaresällskapet, to DG), Academy of Finland (1219001, to DG; 310552, to LP), Wilhelm and Else Stockmann Foundation (to DG), EVO governmental grants (to DG), Perklén Foundation (to DG), University of Helsinki (Clinical Researcher stint, to DG), Hospital District of Helsinki and Uusimaa (TYH2018235, to TM), and Finnish Medical Foundation (to TM).

Publisher Copyright:
© 2023 by the authors.

Fields of Science

1182 Biochemistry, cell and molecular biology
Ffa
N-wasp
Pacsin2
Actin cytoskeleton
Diabetic kidney disease
Podocyte
Syndapin2

Access to Document

10.3390/cells12111487Licence: CC BY

http://hdl.handle.net/10138/358519Licence: CC BY

Cite this

@article{9f4f52c1595e4859a7d188df8057ab57,

title = "Phosphorylation of PACSIN2 at S313 Regulates Podocyte Architecture in Coordination with N-WASP",

keywords = "1182 Biochemistry, cell and molecular biology, Ffa, N-wasp, Pacsin2, Actin cytoskeleton, Diabetic kidney disease, Podocyte, Syndapin2",

author = "Rim Bouslama and Vincent Dumont and Sonja Lindfors and Lassi Paavolainen and Jukka Tienari and Harry Nisen and Tuomas Mirtti and Saleem, {Moin A.} and Daniel Gordin and Groop, {Per Henrik} and Shiro Suetsugu and Sanna Lehtonen",

note = "Funding Information: This work was supported by grants from the Doctoral Programme in Biomedicine (to RB) and Finnish Diabetes Research Foundation (Diabetestutkimuss{\"a}{\"a}ti{\"o}, to RB, VD and SoL), Finnish Kidney Foundation (Munuaiss{\"a}{\"a}ti{\"o}, to RB, VD and SoL), Onni and Hilja Tuovinen Foundation (to RB), Finnish-Norwegian Medical Research Foundation (to SoL), Jalmari and Rauha Ahokas Foundation (to RB and VD), Orion Foundation (to VD), Alfred Kordelin Foundation (to VD), Maud Kuistila Foundation (to VD), HiLife, University of Helsinki (to SaL, DG), Sigrid Jus{\'e}lius Foundation (to SaL, DG), P{\"a}ivikki and Sakari Sohlberg Foundation (to SoL, DG), Liv och H{\"a}lsa Society (to DG), Medical Society of Finland (Finska L{\"a}kares{\"a}llskapet, to DG), Academy of Finland (1219001, to DG; 310552, to LP), Wilhelm and Else Stockmann Foundation (to DG), EVO governmental grants (to DG), Perkl{\'e}n Foundation (to DG), University of Helsinki (Clinical Researcher stint, to DG), Hospital District of Helsinki and Uusimaa (TYH2018235, to TM), and Finnish Medical Foundation (to TM). Publisher Copyright: {\textcopyright} 2023 by the authors.",

year = "2023",

month = may,

day = "27",

doi = "10.3390/cells12111487",

language = "English",

volume = "12",

journal = "Cells",

issn = "2073-4409",

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T1 - Phosphorylation of PACSIN2 at S313 Regulates Podocyte Architecture in Coordination with N-WASP

AU - Bouslama, Rim

AU - Dumont, Vincent

AU - Lindfors, Sonja

AU - Paavolainen, Lassi

AU - Tienari, Jukka

AU - Nisen, Harry

AU - Mirtti, Tuomas

AU - Saleem, Moin A.

AU - Gordin, Daniel

AU - Groop, Per Henrik

AU - Suetsugu, Shiro

AU - Lehtonen, Sanna

N1 - Funding Information: This work was supported by grants from the Doctoral Programme in Biomedicine (to RB) and Finnish Diabetes Research Foundation (Diabetestutkimussäätiö, to RB, VD and SoL), Finnish Kidney Foundation (Munuaissäätiö, to RB, VD and SoL), Onni and Hilja Tuovinen Foundation (to RB), Finnish-Norwegian Medical Research Foundation (to SoL), Jalmari and Rauha Ahokas Foundation (to RB and VD), Orion Foundation (to VD), Alfred Kordelin Foundation (to VD), Maud Kuistila Foundation (to VD), HiLife, University of Helsinki (to SaL, DG), Sigrid Jusélius Foundation (to SaL, DG), Päivikki and Sakari Sohlberg Foundation (to SoL, DG), Liv och Hälsa Society (to DG), Medical Society of Finland (Finska Läkaresällskapet, to DG), Academy of Finland (1219001, to DG; 310552, to LP), Wilhelm and Else Stockmann Foundation (to DG), EVO governmental grants (to DG), Perklén Foundation (to DG), University of Helsinki (Clinical Researcher stint, to DG), Hospital District of Helsinki and Uusimaa (TYH2018235, to TM), and Finnish Medical Foundation (to TM). Publisher Copyright: © 2023 by the authors.

PY - 2023/5/27

Y1 - 2023/5/27

KW - 1182 Biochemistry, cell and molecular biology

KW - Ffa

KW - N-wasp

KW - Pacsin2

KW - Actin cytoskeleton

KW - Diabetic kidney disease

KW - Podocyte

KW - Syndapin2

U2 - 10.3390/cells12111487

DO - 10.3390/cells12111487

M3 - Article

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