Physical and functional interactome atlas of human receptor tyrosine kinases

Kari Salokas; Xiaonan Liu; Tiina Öhman; Iftekhar Chowdhury; Lisa Gawriyski; Salla Keskitalo; Markku Varjosalo

doi:10.15252/embr.202154041

Physical and functional interactome atlas of human receptor tyrosine kinases

Kari Salokas, Xiaonan Liu, Tiina Öhman, Iftekhar Chowdhury, Lisa Gawriyski, Salla Keskitalo, Markku Varjosalo

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Article number	54041
Journal	EMBO Reports
Volume	23
Issue number	6
Number of pages	28
ISSN	1469-221X
DOIs	https://doi.org/10.15252/embr.202154041
Publication status	Published - 7 Jun 2022
MoE publication type	A1 Journal article-refereed

Bibliographical note

Funding Information:
We thank S. Miettinen for technical assistance and Professors Matthias Gstaiger, Aki Manninen, and Kaisa Lehti for critical reading and comments on the manuscript. This study was supported by grants from the Academy of Finland (nos. 288475 and 294173), the Sigrid Jusélius Foundation, the Finnish Cancer Foundation, the University of Helsinki Three‐year Research Grant, Biocentrum Helsinki, Biocentrum Finland, HiLIFE, Magnus Ehrnrooth Foundation, and the Instrumentarium Research Foundation. Open access funding enabled and organized by ProjektDEAL.

Publisher Copyright:
© 2022 The Authors. Published under the terms of the CC BY 4.0 license.

Fields of Science

interaction proteomics
phosphoproteomics
receptor tyrosine kinase
RTK
systems biology
ACTIVATION
GROWTH-FACTOR RECEPTORS
IDENTIFICATION
INHIBITION
PATHWAY
PURIFICATION
RESISTANCE
DEGRADATION
MAP
PHOSPHATASES
1182 Biochemistry, cell and molecular biology

Access to Document

10.15252/embr.202154041Licence: CC BY

EMBO Reports - 2022 - Salokas - Physical and functional interactome atlas of human receptor tyrosine kinasesFinal published version, 1.76 MBLicence: CC BY

Cite this

@article{2dc243d56d184dbdbd18f82373c63330,

title = "Physical and functional interactome atlas of human receptor tyrosine kinases",

keywords = "interaction proteomics, phosphoproteomics, receptor tyrosine kinase, RTK, systems biology, ACTIVATION, GROWTH-FACTOR RECEPTORS, IDENTIFICATION, INHIBITION, PATHWAY, PURIFICATION, RESISTANCE, DEGRADATION, MAP, PHOSPHATASES, 1182 Biochemistry, cell and molecular biology",

author = "Kari Salokas and Xiaonan Liu and Tiina {\"O}hman and Iftekhar Chowdhury and Lisa Gawriyski and Salla Keskitalo and Markku Varjosalo",

note = "Funding Information: We thank S. Miettinen for technical assistance and Professors Matthias Gstaiger, Aki Manninen, and Kaisa Lehti for critical reading and comments on the manuscript. This study was supported by grants from the Academy of Finland (nos. 288475 and 294173), the Sigrid Jus{\'e}lius Foundation, the Finnish Cancer Foundation, the University of Helsinki Three‐year Research Grant, Biocentrum Helsinki, Biocentrum Finland, HiLIFE, Magnus Ehrnrooth Foundation, and the Instrumentarium Research Foundation. Open access funding enabled and organized by ProjektDEAL. Publisher Copyright: {\textcopyright} 2022 The Authors. Published under the terms of the CC BY 4.0 license.",

year = "2022",

month = jun,

day = "7",

doi = "10.15252/embr.202154041",

language = "English",

volume = "23",

journal = "EMBO Reports",

issn = "1469-221X",

publisher = "Wiley",

number = "6",

}

TY - JOUR

T1 - Physical and functional interactome atlas of human receptor tyrosine kinases

AU - Salokas, Kari

AU - Liu, Xiaonan

AU - Öhman, Tiina

AU - Chowdhury, Iftekhar

AU - Gawriyski, Lisa

AU - Keskitalo, Salla

AU - Varjosalo, Markku

N1 - Funding Information: We thank S. Miettinen for technical assistance and Professors Matthias Gstaiger, Aki Manninen, and Kaisa Lehti for critical reading and comments on the manuscript. This study was supported by grants from the Academy of Finland (nos. 288475 and 294173), the Sigrid Jusélius Foundation, the Finnish Cancer Foundation, the University of Helsinki Three‐year Research Grant, Biocentrum Helsinki, Biocentrum Finland, HiLIFE, Magnus Ehrnrooth Foundation, and the Instrumentarium Research Foundation. Open access funding enabled and organized by ProjektDEAL. Publisher Copyright: © 2022 The Authors. Published under the terms of the CC BY 4.0 license.

PY - 2022/6/7

Y1 - 2022/6/7

KW - interaction proteomics

KW - phosphoproteomics

KW - receptor tyrosine kinase

KW - RTK

KW - systems biology

KW - ACTIVATION

KW - GROWTH-FACTOR RECEPTORS

KW - IDENTIFICATION

KW - INHIBITION

KW - PATHWAY

KW - PURIFICATION

KW - RESISTANCE

KW - DEGRADATION

KW - MAP

KW - PHOSPHATASES

KW - 1182 Biochemistry, cell and molecular biology

U2 - 10.15252/embr.202154041

DO - 10.15252/embr.202154041

M3 - Article

AN - SCOPUS:85127556237

SN - 1469-221X

VL - 23

JO - EMBO Reports

JF - EMBO Reports

IS - 6

M1 - 54041

ER -