Plasma N-Glycoproteomics in monozygotic twin pairs discordant for body mass index reveals an obesity signature related to inflammation and iron metabolism

Maheswary Muniandy; Sakari Joenväärä; Birgitta W. van der Kolk; Tiialotta Tohmola; Hanna Haltia; Sina Saari; Antti Hakkarainen; Jesper Lundbom; Juho Kuula; Per-Henrik Groop; Jaakko Kaprio; Sini Heinonen; Risto Renkonen; Kirsi H. Pietiläinen

doi:10.1186/s13062-025-00609-y

Plasma N-Glycoproteomics in monozygotic twin pairs discordant for body mass index reveals an obesity signature related to inflammation and iron metabolism

Maheswary Muniandy, Sakari Joenväärä, Birgitta W. van der Kolk, Tiialotta Tohmola, Hanna Haltia, Sina Saari, Antti Hakkarainen, Jesper Lundbom, Juho Kuula, Per-Henrik Groop, Jaakko Kaprio, Sini Heinonen, Risto Renkonen, Kirsi H. Pietiläinen

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Article number	31
Journal	Biology Direct
Volume	20
Issue number	1
Number of pages	15
ISSN	1745-6150
DOIs	https://doi.org/10.1186/s13062-025-00609-y
Publication status	Published - 19 Mar 2025
MoE publication type	A1 Journal article-refereed

Fields of Science

Monozygotic twin pairs
N-glycosylation
Obesity
Plasma
Proteomics
3121 General medicine, internal medicine and other clinical medicine

Access to Document

10.1186/s13062-025-00609-y

s13062-025-00609-yFinal published version, 2.32 MBLicence: CC BY

Cite this

Muniandy, M., Joenväärä, S., van der Kolk, B. W., Tohmola, T., Haltia, H., Saari, S., Hakkarainen, A., Lundbom, J., Kuula, J., Groop, P.-H., Kaprio, J., Heinonen, S., Renkonen, R., & Pietiläinen, K. H. (2025). Plasma N-Glycoproteomics in monozygotic twin pairs discordant for body mass index reveals an obesity signature related to inflammation and iron metabolism. Biology Direct, 20(1), Article 31. https://doi.org/10.1186/s13062-025-00609-y

@article{ac4e6853f28c460cad0061c680b00775,

title = "Plasma N-Glycoproteomics in monozygotic twin pairs discordant for body mass index reveals an obesity signature related to inflammation and iron metabolism",

keywords = "Monozygotic twin pairs, N-glycosylation, Obesity, Plasma, Proteomics, 3121 General medicine, internal medicine and other clinical medicine",

author = "Maheswary Muniandy and Sakari Joenv{\"a}{\"a}r{\"a} and {van der Kolk}, {Birgitta W.} and Tiialotta Tohmola and Hanna Haltia and Sina Saari and Antti Hakkarainen and Jesper Lundbom and Juho Kuula and Per-Henrik Groop and Jaakko Kaprio and Sini Heinonen and Risto Renkonen and Pietil{\"a}inen, {Kirsi H.}",

year = "2025",

month = mar,

day = "19",

doi = "10.1186/s13062-025-00609-y",

language = "English",

volume = "20",

journal = "Biology Direct",

issn = "1745-6150",

publisher = "BioMed Central Ltd",

number = "1",

}

Muniandy, M , Joenväärä, S, van der Kolk, BW, Tohmola, T, Haltia, H, Saari, S , Hakkarainen, A , Lundbom, J , Kuula, J , Groop, P-H , Kaprio, J, Heinonen, S, Renkonen, R & Pietiläinen, KH 2025, 'Plasma N-Glycoproteomics in monozygotic twin pairs discordant for body mass index reveals an obesity signature related to inflammation and iron metabolism', Biology Direct, vol. 20, no. 1, 31. https://doi.org/10.1186/s13062-025-00609-y

TY - JOUR

T1 - Plasma N-Glycoproteomics in monozygotic twin pairs discordant for body mass index reveals an obesity signature related to inflammation and iron metabolism

AU - Muniandy, Maheswary

AU - Joenväärä, Sakari

AU - van der Kolk, Birgitta W.

AU - Tohmola, Tiialotta

AU - Haltia, Hanna

AU - Saari, Sina

AU - Hakkarainen, Antti

AU - Lundbom, Jesper

AU - Kuula, Juho

AU - Groop, Per-Henrik

AU - Kaprio, Jaakko

AU - Heinonen, Sini

AU - Renkonen, Risto

AU - Pietiläinen, Kirsi H.

PY - 2025/3/19

Y1 - 2025/3/19

KW - Monozygotic twin pairs

KW - N-glycosylation

KW - Obesity

KW - Plasma

KW - Proteomics

KW - 3121 General medicine, internal medicine and other clinical medicine

U2 - 10.1186/s13062-025-00609-y

DO - 10.1186/s13062-025-00609-y

M3 - Article

C2 - 40108677

SN - 1745-6150

VL - 20

JO - Biology Direct

JF - Biology Direct

IS - 1

M1 - 31

ER -