Platelet-Specific PDGFB Ablation Impairs Tumor Vessel Integrity and Promotes Metastasis

Yanyu Zhang; Jessica Cedervall; Anahita Hamidi; Melanie Herre; Kati Viitaniemi; Gabriela D'Amico; Zuoxiu Miao; Ragaseema Valsala Madhavan Unnithan; Alessandra Vaccaro; Luuk van Hooren; Maria Georganaki; Asa Thulin; Qi Qiao; Johanna Andrae; Agneta Siegbahn; Carl-Henrik Heldin; Kari Alitalo; Christer Betsholtz; Anna Dimberg; Anna-Karin Olsson

doi:10.1158/0008-5472.CAN-19-3533

Platelet-Specific PDGFB Ablation Impairs Tumor Vessel Integrity and Promotes Metastasis

Yanyu Zhang, Jessica Cedervall, Anahita Hamidi, Melanie Herre, Kati Viitaniemi, Gabriela D'Amico, Zuoxiu Miao, Ragaseema Valsala Madhavan Unnithan, Alessandra Vaccaro, Luuk van Hooren, Maria Georganaki, Asa Thulin, Qi Qiao, Johanna Andrae, Agneta Siegbahn, Carl-Henrik Heldin, Kari Alitalo, Christer Betsholtz, Anna Dimberg, Anna-Karin Olsson

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	Cancer Research
Volume	80
Issue number	16
Pages (from-to)	3345-3358
Number of pages	14
ISSN	0008-5472
DOIs	https://doi.org/10.1158/0008-5472.CAN-19-3533
Publication status	Published - 15 Aug 2020
MoE publication type	A1 Journal article-refereed

Fields of Science

GROWTH-FACTOR
MESENCHYMAL TRANSITION
ENDOTHELIAL-CELLS
BLOOD-VESSELS
PERICYTE LOSS
B RETENTION
BETA
CANCER
ANGIOGENESIS
ABNORMALITIES
3122 Cancers

Access to Document

10.1158/0008-5472.CAN-19-3533

Cite this

Zhang, Y., Cedervall, J., Hamidi, A., Herre, M., Viitaniemi, K., D'Amico, G., Miao, Z., Unnithan, R. V. M., Vaccaro, A., van Hooren, L., Georganaki, M., Thulin, A., Qiao, Q., Andrae, J., Siegbahn, A., Heldin, C.-H., Alitalo, K., Betsholtz, C., Dimberg, A., & Olsson, A.-K. (2020). Platelet-Specific PDGFB Ablation Impairs Tumor Vessel Integrity and Promotes Metastasis. Cancer Research, 80(16), 3345-3358. https://doi.org/10.1158/0008-5472.CAN-19-3533

@article{907c8f31ea5e44fab9e79635f52b126e,

title = "Platelet-Specific PDGFB Ablation Impairs Tumor Vessel Integrity and Promotes Metastasis",

keywords = "GROWTH-FACTOR, MESENCHYMAL TRANSITION, ENDOTHELIAL-CELLS, BLOOD-VESSELS, PERICYTE LOSS, B RETENTION, BETA, CANCER, ANGIOGENESIS, ABNORMALITIES, 3122 Cancers",

author = "Yanyu Zhang and Jessica Cedervall and Anahita Hamidi and Melanie Herre and Kati Viitaniemi and Gabriela D'Amico and Zuoxiu Miao and Unnithan, \{Ragaseema Valsala Madhavan\} and Alessandra Vaccaro and \{van Hooren\}, Luuk and Maria Georganaki and Asa Thulin and Qi Qiao and Johanna Andrae and Agneta Siegbahn and Carl-Henrik Heldin and Kari Alitalo and Christer Betsholtz and Anna Dimberg and Anna-Karin Olsson",

year = "2020",

month = aug,

day = "15",

doi = "10.1158/0008-5472.CAN-19-3533",

language = "English",

volume = "80",

pages = "3345--3358",

journal = "Cancer Research",

issn = "0008-5472",

publisher = "American Association for Cancer Research Inc.",

number = "16",

}

Zhang, Y, Cedervall, J, Hamidi, A, Herre, M, Viitaniemi, K, D'Amico, G, Miao, Z, Unnithan, RVM, Vaccaro, A, van Hooren, L, Georganaki, M, Thulin, A, Qiao, Q, Andrae, J, Siegbahn, A, Heldin, C-H, Alitalo, K, Betsholtz, C, Dimberg, A & Olsson, A-K 2020, 'Platelet-Specific PDGFB Ablation Impairs Tumor Vessel Integrity and Promotes Metastasis', Cancer Research, vol. 80, no. 16, pp. 3345-3358. https://doi.org/10.1158/0008-5472.CAN-19-3533

TY - JOUR

T1 - Platelet-Specific PDGFB Ablation Impairs Tumor Vessel Integrity and Promotes Metastasis

AU - Zhang, Yanyu

AU - Cedervall, Jessica

AU - Hamidi, Anahita

AU - Herre, Melanie

AU - Viitaniemi, Kati

AU - D'Amico, Gabriela

AU - Miao, Zuoxiu

AU - Unnithan, Ragaseema Valsala Madhavan

AU - Vaccaro, Alessandra

AU - van Hooren, Luuk

AU - Georganaki, Maria

AU - Thulin, Asa

AU - Qiao, Qi

AU - Andrae, Johanna

AU - Siegbahn, Agneta

AU - Heldin, Carl-Henrik

AU - Alitalo, Kari

AU - Betsholtz, Christer

AU - Dimberg, Anna

AU - Olsson, Anna-Karin

PY - 2020/8/15

Y1 - 2020/8/15

KW - GROWTH-FACTOR

KW - MESENCHYMAL TRANSITION

KW - ENDOTHELIAL-CELLS

KW - BLOOD-VESSELS

KW - PERICYTE LOSS

KW - B RETENTION

KW - BETA

KW - CANCER

KW - ANGIOGENESIS

KW - ABNORMALITIES

KW - 3122 Cancers

U2 - 10.1158/0008-5472.CAN-19-3533

DO - 10.1158/0008-5472.CAN-19-3533

M3 - Article

SN - 0008-5472

VL - 80

SP - 3345

EP - 3358

JO - Cancer Research

JF - Cancer Research

IS - 16

ER -