PNPLA3 is regulated by glucose in human hepatocytes, and its I148M mutant slows down triglyceride hydrolysis

Julia Perttilä, Carolina Huaman-Samanez, Sandrine Caron, Kimmo Tanhuanpaa, Bart Staels, Hannele Yki-Järvinen, Vesa Olkkonen

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalAmerican Journal of Physiology: Endocrinology and Metabolism
Volume302
Issue number9
Pages (from-to)E1063-E1069
Number of pages7
ISSN0193-1849
DOIs
Publication statusPublished - 2012
MoE publication typeA1 Journal article-refereed

Fields of Science

  • patatin-like phospholipase domain-containing 3
  • isoleucine to methionine change at position 148
  • NONALCOHOLIC FATTY LIVER
  • ELEMENT-BINDING PROTEIN
  • ADIPONUTRIN/PNPLA3 GENE
  • HISTOLOGICAL SEVERITY
  • DISEASE
  • VARIANT
  • SUSCEPTIBILITY
  • ASSOCIATION
  • METABOLISM
  • EXPRESSION
  • 3121 Internal medicine

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