Polygenic risk for neuroticism is associated with externalizing symptoms in 2-year-old boys

Johanna Liuhanen; Katri Kantojärvi; Henriette Acosta; Johanna T. Pietikäinen; Saara Nolvi; Minna Savukoski; Anneli Kylliäinen; Pirjo Pölkki; Hasse Karlsson; Linnea Karlsson; E. Juulia Paavonen; Tiina Paunio

doi:10.1016/j.pnpbp.2023.110720

Polygenic risk for neuroticism is associated with externalizing symptoms in 2-year-old boys

Johanna Liuhanen, Katri Kantojärvi, Henriette Acosta, Johanna T. Pietikäinen, Saara Nolvi, Minna Savukoski, Anneli Kylliäinen, Pirjo Pölkki, Hasse Karlsson, Linnea Karlsson, E. Juulia Paavonen, Tiina Paunio

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Article number	110720
Journal	Progress in Neuro-Psychopharmacology and Biological Psychiatry
Volume	123
Number of pages	8
ISSN	0278-5846
DOIs	https://doi.org/10.1016/j.pnpbp.2023.110720
Publication status	Published - 20 Apr 2023
MoE publication type	A1 Journal article-refereed

Bibliographical note

Funding Information:
The study was supported by the Academy of Finland (#308589 and #325292/Profi 5 LK; #308588 and #342747 EJP; #134880 and #253346 TP), Finnish State Grants for Clinical Research (ERVA) (LK) , Signe and Ane Gyllenberg Foundation (LK and TP).

Publisher Copyright:
© 2023 The Authors

Fields of Science

Early childhood
Externalizing symptoms
Internalizing symptoms
Neuroticism
Polygenic scores
3123 Gynaecology and paediatrics
3124 Neurology and psychiatry

Access to Document

10.1016/j.pnpbp.2023.110720Licence: CC BY

1-s2.0-S0278584623000064-mainFinal published version, 1.41 MBLicence: CC BY

Cite this

Liuhanen, J., Kantojärvi, K., Acosta, H., Pietikäinen, J. T., Nolvi, S., Savukoski, M., Kylliäinen, A., Pölkki, P., Karlsson, H., Karlsson, L., Paavonen, E. J., & Paunio, T. (2023). Polygenic risk for neuroticism is associated with externalizing symptoms in 2-year-old boys. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 123, Article 110720. https://doi.org/10.1016/j.pnpbp.2023.110720

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title = "Polygenic risk for neuroticism is associated with externalizing symptoms in 2-year-old boys",

keywords = "Early childhood, Externalizing symptoms, Internalizing symptoms, Neuroticism, Polygenic scores, 3123 Gynaecology and paediatrics, 3124 Neurology and psychiatry",

author = "Johanna Liuhanen and Katri Kantoj{\"a}rvi and Henriette Acosta and Pietik{\"a}inen, {Johanna T.} and Saara Nolvi and Minna Savukoski and Anneli Kylli{\"a}inen and Pirjo P{\"o}lkki and Hasse Karlsson and Linnea Karlsson and Paavonen, {E. Juulia} and Tiina Paunio",

note = "Funding Information: The study was supported by the Academy of Finland (#308589 and #325292/Profi 5 LK; #308588 and #342747 EJP; #134880 and #253346 TP), Finnish State Grants for Clinical Research (ERVA) (LK) , Signe and Ane Gyllenberg Foundation (LK and TP). Publisher Copyright: {\textcopyright} 2023 The Authors",

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Liuhanen, J , Kantojärvi, K, Acosta, H, Pietikäinen, JT, Nolvi, S, Savukoski, M, Kylliäinen, A, Pölkki, P, Karlsson, H, Karlsson, L, Paavonen, EJ & Paunio, T 2023, 'Polygenic risk for neuroticism is associated with externalizing symptoms in 2-year-old boys', Progress in Neuro-Psychopharmacology and Biological Psychiatry, vol. 123, 110720. https://doi.org/10.1016/j.pnpbp.2023.110720

TY - JOUR

T1 - Polygenic risk for neuroticism is associated with externalizing symptoms in 2-year-old boys

AU - Liuhanen, Johanna

AU - Kantojärvi, Katri

AU - Acosta, Henriette

AU - Pietikäinen, Johanna T.

AU - Nolvi, Saara

AU - Savukoski, Minna

AU - Kylliäinen, Anneli

AU - Pölkki, Pirjo

AU - Karlsson, Hasse

AU - Karlsson, Linnea

AU - Paavonen, E. Juulia

AU - Paunio, Tiina

N1 - Funding Information: The study was supported by the Academy of Finland (#308589 and #325292/Profi 5 LK; #308588 and #342747 EJP; #134880 and #253346 TP), Finnish State Grants for Clinical Research (ERVA) (LK) , Signe and Ane Gyllenberg Foundation (LK and TP). Publisher Copyright: © 2023 The Authors

PY - 2023/4/20

Y1 - 2023/4/20

KW - Early childhood

KW - Externalizing symptoms

KW - Internalizing symptoms

KW - Neuroticism

KW - Polygenic scores

KW - 3123 Gynaecology and paediatrics

KW - 3124 Neurology and psychiatry

U2 - 10.1016/j.pnpbp.2023.110720

DO - 10.1016/j.pnpbp.2023.110720

M3 - Article

C2 - 36649821

AN - SCOPUS:85146346432

SN - 0278-5846

VL - 123

JO - Progress in Neuro-Psychopharmacology and Biological Psychiatry

JF - Progress in Neuro-Psychopharmacology and Biological Psychiatry

M1 - 110720

ER -