Polygenic risk scores and breast and epithelial ovarian cancer risks for carriers of BRCA1 and BRCA2 pathogenic variants

GEMO Study Collaborators, EMBRACE Collaborators, kConFab Investigators, HEBON Investigators, GENEPSO Investigators, Consortium Investigators Modifiers, Daniel R. Barnes, Matti A. Rookus, Lesley McGuffog, Kristiina Aittomäki

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalGenetics In medicine
Volume22
Issue number10
Pages (from-to)1653-1666
Number of pages14
ISSN1098-3600
DOIs
Publication statusPublished - Oct 2020
MoE publication typeA1 Journal article-refereed

Fields of Science

  • BRCA1
  • 2
  • breast cancer
  • ovarian cancer
  • PRS
  • genetics
  • MUTATION CARRIERS
  • SUSCEPTIBILITY
  • ASSOCIATION
  • PATHOLOGY
  • IDENTIFICATION
  • MODIFIERS
  • ALLELES
  • MODEL
  • 3111 Biomedicine
  • 1184 Genetics, developmental biology, physiology
  • 3123 Gynaecology and paediatrics
  • 3122 Cancers

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