Population pharmacokinetics of S-ketamine and norketamine in healthy volunteers after intravenous and oral dosing

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalEuropean Journal of Clinical Pharmacology
Volume71
Issue number4
Pages (from-to)441-447
Number of pages7
ISSN0031-6970
DOIs
Publication statusPublished - Apr 2015
MoE publication typeA1 Journal article-refereed

Fields of Science

  • Ketamine
  • S-ketamine
  • Norketamine
  • Population pharmacokinetics
  • CYP2B6
  • CYP3A4
  • First-pass effect
  • Well-stirred model
  • HUMAN LIVER-MICROSOMES
  • ACUTE POSTOPERATIVE PAIN
  • COMPARATIVE PHARMACOLOGY
  • PERIOPERATIVE KETAMINE
  • N-DEMETHYLATION
  • DEPRESSION
  • S(+)-KETAMINE
  • METABOLITES
  • CONSUMPTION
  • MANAGEMENT
  • 317 Pharmacy

Cite this

@article{55bd8e85b9184f538f2766af597c6e91,
title = "Population pharmacokinetics of S-ketamine and norketamine in healthy volunteers after intravenous and oral dosing",
keywords = "Ketamine, S-ketamine, Norketamine, Population pharmacokinetics, CYP2B6, CYP3A4, First-pass effect, Well-stirred model, HUMAN LIVER-MICROSOMES, ACUTE POSTOPERATIVE PAIN, COMPARATIVE PHARMACOLOGY, PERIOPERATIVE KETAMINE, N-DEMETHYLATION, DEPRESSION, S(+)-KETAMINE, METABOLITES, CONSUMPTION, MANAGEMENT, 317 Pharmacy",
author = "Samuel Fanta and Mari Kinnunen and Backman, {Janne T.} and Eija Kalso",
year = "2015",
month = "4",
doi = "10.1007/s00228-015-1826-y",
language = "English",
volume = "71",
pages = "441--447",
journal = "European Journal of Clinical Pharmacology",
issn = "0031-6970",
publisher = "Springer Heidelberg",
number = "4",

}

Population pharmacokinetics of S-ketamine and norketamine in healthy volunteers after intravenous and oral dosing. / Fanta, Samuel; Kinnunen, Mari; Backman, Janne T.; Kalso, Eija.

In: European Journal of Clinical Pharmacology, Vol. 71, No. 4, 04.2015, p. 441-447.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Population pharmacokinetics of S-ketamine and norketamine in healthy volunteers after intravenous and oral dosing

AU - Fanta, Samuel

AU - Kinnunen, Mari

AU - Backman, Janne T.

AU - Kalso, Eija

PY - 2015/4

Y1 - 2015/4

KW - Ketamine

KW - S-ketamine

KW - Norketamine

KW - Population pharmacokinetics

KW - CYP2B6

KW - CYP3A4

KW - First-pass effect

KW - Well-stirred model

KW - HUMAN LIVER-MICROSOMES

KW - ACUTE POSTOPERATIVE PAIN

KW - COMPARATIVE PHARMACOLOGY

KW - PERIOPERATIVE KETAMINE

KW - N-DEMETHYLATION

KW - DEPRESSION

KW - S(+)-KETAMINE

KW - METABOLITES

KW - CONSUMPTION

KW - MANAGEMENT

KW - 317 Pharmacy

U2 - 10.1007/s00228-015-1826-y

DO - 10.1007/s00228-015-1826-y

M3 - Article

VL - 71

SP - 441

EP - 447

JO - European Journal of Clinical Pharmacology

JF - European Journal of Clinical Pharmacology

SN - 0031-6970

IS - 4

ER -