Projects per year
Abstract
Background and purpose: Post-stroke cognitive impairment is a common and well-known consequence of supra-tentorial infarct, but its prevalence and severity after infra-tentorial infarct is unclear. We compared the frequencies and prognostic value of domain-specific cognitive deficits after supra-tentorial and infra-tentorial infarct. Methods: In a consecutive cohort of patients with first-ever stroke (N = 244) admitted to Helsinki University Hospital, 37 patients had an infra-tentorial infarct. Patients were assessed with a comprehensive neuropsychological examination 3 months post-stroke covering 9 cognitive domains and functional disability was assessed at 15 months with the modified Rankin Scale. Results: There were no statistically significant differences between the frequencies of cognitive deficits in patients with infra-tentorial vs supra-tentorial infarct. Altogether 73% of patients with infra-tentorial infarct and 82% of patients with supra-tentorial infarct had impairment in at least one cognitive domain. Further 42% of patients with infra-tentorial infarct and 47% of those with supra-tentorial infarct had deficits in 3 or more cognitive domains. In patients with infra-tentorial infarct, visuo-constructional deficits were significantly associated with functional disability at 15 months (OR 9.0, 95%CI 1.3-62.5, p = 0.027). In patients with supratentorial infarct, executive deficits (OR 2.9, 95%CI 1.5-5.8, p = 0.002) and visuo-constructional deficits (OR 2.9, 95%CI 1.5-5.7, p = 0.001) showed associations with functional disability at 15 months. Conclusion: Cognitive deficits are as common in patients with infra-tentorial infarct as in those with supra-tentorial infarct, and it is important to recognize them to meet the needs of rehabilitation.
Original language | English |
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Article number | 106108 |
Journal | Journal of Stroke & Cerebrovascular Diseases |
Volume | 30 |
Issue number | 12 |
Number of pages | 5 |
ISSN | 1052-3057 |
DOIs | |
Publication status | Published - Dec 2021 |
MoE publication type | A1 Journal article-refereed |
Fields of Science
- 515 Psychology
- 3124 Neurology and psychiatry
Projects
- 1 Finished
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SAM: Helsinki Stroke Aging Memory Study
Erkinjuntti, T. J. (Project manager), Melkas, S. (Participant), Jokinen, H. (Participant), Hietanen, M. H. (Participant), Sibolt, G. (Participant), Curtze, S. T. (Participant), Laakso, H. (Participant), Pohjasvaara, T. (Participant), Mäntylä, R. (Participant) & Vataja, R. (Participant)
01/01/1993 → 31/07/2019
Project: Research project