Potato virus A particles – A versatile material for self-assembled nanopatterned surfaces

De Swarnalok, Hoang Nguyen, Ville Liljeström, Kristiina Mäkinen, Mauri Kostiainen, Jaana Vapaakallio

Research output: Contribution to journalArticleScientificpeer-review


Potato virus A (PVA) is a plant-infecting RNA virus that produces flexible particles with a high aspect ratio. PVA has been investigated extensively for its infection biology, however, its potential to serve as a nanopatterning platform remains unexplored. Here, we study the liquid crystal and interfacial self-assembly behavior of PVA particles. Furthermore, we generate nanopatterned surfaces using self-assembled PVA particles through three different coating techniques: drop-casting, drop-top deposition and flow-coating. The liquid crystal phase of PVA solution visualized by polarized optical microscopy revealed a chiral nematic phase in water, while in pH 8 buffer it produced a nematic phase. This allowed us to produce thin films with either randomly or anisotropically oriented cylindrical nanopatterns using drop-top and flow-coating methods. Overall, this study explores the self-assembly process of PVA in different conditions, establishing a starting point for PVA self-assembly research and contributing a virus-assisted fabrication technique for nanopatterned surfaces.
Original languageEnglish
Pages (from-to)103-110
Number of pages8
Publication statusPublished - Jan 2023
MoE publication typeA1 Journal article-refereed

Fields of Science

  • 216 Materials engineering
  • Potato virus A Self-assembly Virus nanoparticles Bio-templates Liquid crystal Nanopatterning

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