Potent mechanism-based inhibition of CYP3A4 by imatinib explains its liability to interact with CYP3A4 substrates

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalBritish Journal of Pharmacology
Volume165
Issue number8
Pages (from-to)2787-2798
Number of pages12
ISSN0007-1188
DOIs
Publication statusPublished - 2012
MoE publication typeA1 Journal article-refereed

Fields of Science

  • 3111 Biomedicine

Cite this

@article{4da3f15043ff4f55ba317d39d7414089,
title = "Potent mechanism-based inhibition of CYP3A4 by imatinib explains its liability to interact with CYP3A4 substrates",
keywords = "3111 Biomedicine",
author = "Filppula, {Anne M.} and Jouko Laitila and Neuvonen, {Pertti J.} and Backman, {Janne T.}",
year = "2012",
doi = "10.1111/j.1476-5381.2011.01732.x",
language = "English",
volume = "165",
pages = "2787--2798",
journal = "British Journal of Pharmacology",
issn = "0007-1188",
publisher = "Wiley",
number = "8",

}

Potent mechanism-based inhibition of CYP3A4 by imatinib explains its liability to interact with CYP3A4 substrates. / Filppula, Anne M.; Laitila, Jouko; Neuvonen, Pertti J.; Backman, Janne T.

In: British Journal of Pharmacology, Vol. 165, No. 8, 2012, p. 2787-2798.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Potent mechanism-based inhibition of CYP3A4 by imatinib explains its liability to interact with CYP3A4 substrates

AU - Filppula, Anne M.

AU - Laitila, Jouko

AU - Neuvonen, Pertti J.

AU - Backman, Janne T.

PY - 2012

Y1 - 2012

KW - 3111 Biomedicine

U2 - 10.1111/j.1476-5381.2011.01732.x

DO - 10.1111/j.1476-5381.2011.01732.x

M3 - Article

VL - 165

SP - 2787

EP - 2798

JO - British Journal of Pharmacology

JF - British Journal of Pharmacology

SN - 0007-1188

IS - 8

ER -