PP2A methylesterase PME-1 suppresses anoikis and is associated with therapy relapse of PTEN-deficient prostate cancers

Anna Aakula; Aleksi Isomursu; Christian Rupp; Andrew Erickson; Nikhil Gupta; Otto Kauko; Pragya Shah; Artur Padzik; Yuba Raj Pokharel; Amanpreet Kaur; Song-Ping Li; Lloyd Trotman; Pekka Taimen; Antti Rannikko; Jan Lammerding; Ilkka Paatero; Tuomas Mirtti; Johanna Ivaska; Jukka Westermarck

doi:10.1002/1878-0261.13353

PP2A methylesterase PME-1 suppresses anoikis and is associated with therapy relapse of PTEN-deficient prostate cancers

Anna Aakula, Aleksi Isomursu, Christian Rupp, Andrew Erickson, Nikhil Gupta, Otto Kauko, Pragya Shah, Artur Padzik, Yuba Raj Pokharel, Amanpreet Kaur, Song-Ping Li, Lloyd Trotman, Pekka Taimen, Antti Rannikko, Jan Lammerding, Ilkka Paatero, Tuomas Mirtti, Johanna Ivaska, Jukka Westermarck

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	Molecular oncology
Volume	17
Issue number	6
Pages (from-to)	1007-1023
Number of pages	17
ISSN	1574-7891
DOIs	https://doi.org/10.1002/1878-0261.13353
Publication status	Published - Jun 2023
MoE publication type	A1 Journal article-refereed

Fields of Science

3122 Cancers

Access to Document

10.1002/1878-0261.13353

Molecular Oncology - 2022 - Aakula - PP2A methylesterase PME‐1 suppresses anoikis and is associated with therapy relapse ofFinal published version, 2.02 MBLicence: CC BY

Cite this

Aakula, A., Isomursu, A., Rupp, C., Erickson, A., Gupta, N., Kauko, O., Shah, P., Padzik, A., Pokharel, Y. R., Kaur, A., Li, S.-P., Trotman, L., Taimen, P., Rannikko, A., Lammerding, J., Paatero, I., Mirtti, T., Ivaska, J., & Westermarck, J. (2023). PP2A methylesterase PME-1 suppresses anoikis and is associated with therapy relapse of PTEN-deficient prostate cancers. Molecular oncology, 17(6), 1007-1023. https://doi.org/10.1002/1878-0261.13353

@article{472a2ea3d8184350a2de007b02c53a9e,

title = "PP2A methylesterase PME-1 suppresses anoikis and is associated with therapy relapse of PTEN-deficient prostate cancers",

keywords = "Lap2a/b, PP2A-C methylation, Ppme1, Anoikis, Integrin, Nuclear lamina, 3122 Cancers",

author = "Anna Aakula and Aleksi Isomursu and Christian Rupp and Andrew Erickson and Nikhil Gupta and Otto Kauko and Pragya Shah and Artur Padzik and Pokharel, {Yuba Raj} and Amanpreet Kaur and Song-Ping Li and Lloyd Trotman and Pekka Taimen and Antti Rannikko and Jan Lammerding and Ilkka Paatero and Tuomas Mirtti and Johanna Ivaska and Jukka Westermarck",

year = "2023",

month = jun,

doi = "10.1002/1878-0261.13353",

language = "English",

volume = "17",

pages = "1007--1023",

journal = "Molecular oncology",

issn = "1574-7891",

publisher = "Wiley",

number = "6",

}

Aakula, A, Isomursu, A, Rupp, C, Erickson, A, Gupta, N, Kauko, O, Shah, P, Padzik, A, Pokharel, YR, Kaur, A, Li, S-P, Trotman, L, Taimen, P, Rannikko, A, Lammerding, J, Paatero, I, Mirtti, T, Ivaska, J & Westermarck, J 2023, 'PP2A methylesterase PME-1 suppresses anoikis and is associated with therapy relapse of PTEN-deficient prostate cancers', Molecular oncology, vol. 17, no. 6, pp. 1007-1023. https://doi.org/10.1002/1878-0261.13353

TY - JOUR

T1 - PP2A methylesterase PME-1 suppresses anoikis and is associated with therapy relapse of PTEN-deficient prostate cancers

AU - Aakula, Anna

AU - Isomursu, Aleksi

AU - Rupp, Christian

AU - Erickson, Andrew

AU - Gupta, Nikhil

AU - Kauko, Otto

AU - Shah, Pragya

AU - Padzik, Artur

AU - Pokharel, Yuba Raj

AU - Kaur, Amanpreet

AU - Li, Song-Ping

AU - Trotman, Lloyd

AU - Taimen, Pekka

AU - Rannikko, Antti

AU - Lammerding, Jan

AU - Paatero, Ilkka

AU - Mirtti, Tuomas

AU - Ivaska, Johanna

AU - Westermarck, Jukka

PY - 2023/6

Y1 - 2023/6

KW - Lap2a/b

KW - PP2A-C methylation

KW - Ppme1

KW - Anoikis

KW - Integrin

KW - Nuclear lamina

KW - 3122 Cancers

U2 - 10.1002/1878-0261.13353

DO - 10.1002/1878-0261.13353

M3 - Article

C2 - 36461911

SN - 1574-7891

VL - 17

SP - 1007

EP - 1023

JO - Molecular oncology

JF - Molecular oncology

IS - 6

ER -