Pre-α-pro-GDNF and Pre-β-pro-GDNF Isoforms Are Neuroprotective in the 6-hydroxydopamine Rat Model of Parkinson's Disease

Anna-Maija Penttinen, Ilmari Parkkinen, Merja H. Voutilainen, Maryna Koskela, Susanne Bäck, Anna Their, Christopher T. Richie, Andrii Domanskyi, Brandon K. Harvey, Raimo K. Tuominen, Liina Nevalaita, Mart Saarma, Mikko Airavaara

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
Article number457
JournalFrontiers in neurology
Volume9
Number of pages14
ISSN1664-2295
DOIs
Publication statusPublished - 20 Jun 2018
MoE publication typeA1 Journal article-refereed

Fields of Science

  • neurotrophic factors
  • neurodegeneration
  • GDNF
  • splice variant
  • alternative splicing
  • tyrosine hydroxylase
  • dopamine
  • MIDBRAIN DOPAMINERGIC-NEURONS
  • CONVECTION-ENHANCED DELIVERY
  • INTRASTRIATAL 6-OHDA LESION
  • AGED FISCHER-344 RATS
  • NEUROTROPHIC FACTOR
  • IN-VIVO
  • TYROSINE-HYDROXYLASE
  • LENTIVIRAL VECTOR
  • NIGROSTRIATAL PATHWAY
  • GENE-TRANSFER
  • 3112 Neurosciences

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