Prediction of overall survival for patients with metastatic castration-resistant prostate cancer: development of a prognostic model through a crowdsourced challenge with open clinical trial data

Justin Guinney; Tao Wang; Teemu D. Laajala; Kimberly Kanigel Winner; J. Christopher Bare; Elias Chaibub Neto; Suleiman A. Khan; Gopal Peddinti; Antti Airola; Tapio Pahikkala; Tuomas Mirtti; Thomas Yu; Brian M. Bot; Liji Shen; Kald Abdallah; Thea Norman; Stephen Friend; Gustavo Stolovitzky; Howard Soule; Christopher J. Sweeney; Charles J. Ryan; Howard I. Scher; Oliver Sartor; Yang Xie; Tero Aittokallio; Fang Liz Zhou; James C. Costello; Prostate Canc Challenge DREAM Comm

doi:10.1016/S1470-2045(16)30560-5

Prediction of overall survival for patients with metastatic castration-resistant prostate cancer: development of a prognostic model through a crowdsourced challenge with open clinical trial data

Justin Guinney, Tao Wang, Teemu D. Laajala, Kimberly Kanigel Winner, J. Christopher Bare, Elias Chaibub Neto, Suleiman A. Khan, Gopal Peddinti, Antti Airola, Tapio Pahikkala, Tuomas Mirtti, Thomas Yu, Brian M. Bot, Liji Shen, Kald Abdallah, Thea Norman, Stephen Friend, Gustavo Stolovitzky, Howard Soule, Christopher J. SweeneyCharles J. Ryan, Howard I. Scher, Oliver Sartor, Yang Xie, Tero Aittokallio, Fang Liz Zhou, James C. Costello, Prostate Canc Challenge DREAM Comm

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	Lancet Oncology
Volume	18
Issue number	1
Pages (from-to)	132-142
Number of pages	11
ISSN	1470-2045
DOIs	https://doi.org/10.1016/S1470-2045(16)30560-5
Publication status	Published - Jan 2017
MoE publication type	A1 Journal article-refereed

Fields of Science

SIPULEUCEL-T IMMUNOTHERAPY
BIOMEDICAL-RESEARCH
DOUBLE-BLIND
PHASE-III
CHEMOTHERAPY
DOCETAXEL
PREDNISONE
PLACEBO
MEN
ENZALUTAMIDE
3122 Cancers

Access to Document

10.1016/S1470-2045(16)30560-5

PredictionFinal published version, 702 KB

Cite this

Guinney, J., Wang, T., Laajala, T. D., Winner, K. K., Bare, J. C., Neto, E. C., Khan, S. A., Peddinti, G., Airola, A., Pahikkala, T., Mirtti, T., Yu, T., Bot, B. M., Shen, L., Abdallah, K., Norman, T., Friend, S., Stolovitzky, G., Soule, H., ... Prostate Canc Challenge DREAM Comm (2017). Prediction of overall survival for patients with metastatic castration-resistant prostate cancer: development of a prognostic model through a crowdsourced challenge with open clinical trial data. Lancet Oncology, 18(1), 132-142. https://doi.org/10.1016/S1470-2045(16)30560-5

@article{7cdd44c8ecbf460884f89ff0aa77a35d,

title = "Prediction of overall survival for patients with metastatic castration-resistant prostate cancer: development of a prognostic model through a crowdsourced challenge with open clinical trial data",

keywords = "SIPULEUCEL-T IMMUNOTHERAPY, BIOMEDICAL-RESEARCH, DOUBLE-BLIND, PHASE-III, CHEMOTHERAPY, DOCETAXEL, PREDNISONE, PLACEBO, MEN, ENZALUTAMIDE, 3122 Cancers",

author = "Justin Guinney and Tao Wang and Laajala, {Teemu D.} and Winner, {Kimberly Kanigel} and Bare, {J. Christopher} and Neto, {Elias Chaibub} and Khan, {Suleiman A.} and Gopal Peddinti and Antti Airola and Tapio Pahikkala and Tuomas Mirtti and Thomas Yu and Bot, {Brian M.} and Liji Shen and Kald Abdallah and Thea Norman and Stephen Friend and Gustavo Stolovitzky and Howard Soule and Sweeney, {Christopher J.} and Ryan, {Charles J.} and Scher, {Howard I.} and Oliver Sartor and Yang Xie and Tero Aittokallio and Zhou, {Fang Liz} and Costello, {James C.} and {Prostate Canc Challenge DREAM Comm}",

year = "2017",

month = jan,

doi = "10.1016/S1470-2045(16)30560-5",

language = "English",

volume = "18",

pages = "132--142",

journal = "Lancet Oncology",

issn = "1470-2045",

publisher = "EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC",

number = "1",

}

Guinney, J, Wang, T, Laajala, TD, Winner, KK, Bare, JC, Neto, EC, Khan, SA, Peddinti, G, Airola, A, Pahikkala, T, Mirtti, T, Yu, T, Bot, BM, Shen, L, Abdallah, K, Norman, T, Friend, S, Stolovitzky, G, Soule, H, Sweeney, CJ, Ryan, CJ, Scher, HI, Sartor, O, Xie, Y, Aittokallio, T, Zhou, FL, Costello, JC & Prostate Canc Challenge DREAM Comm 2017, 'Prediction of overall survival for patients with metastatic castration-resistant prostate cancer: development of a prognostic model through a crowdsourced challenge with open clinical trial data', Lancet Oncology, vol. 18, no. 1, pp. 132-142. https://doi.org/10.1016/S1470-2045(16)30560-5

Prediction of overall survival for patients with metastatic castration-resistant prostate cancer: development of a prognostic model through a crowdsourced challenge with open clinical trial data. / Guinney, Justin; Wang, Tao; Laajala, Teemu D. et al.
In: Lancet Oncology, Vol. 18, No. 1, 01.2017, p. 132-142.

Research output: Contribution to journal › Article › Scientific › peer-review

TY - JOUR

T1 - Prediction of overall survival for patients with metastatic castration-resistant prostate cancer

T2 - development of a prognostic model through a crowdsourced challenge with open clinical trial data

AU - Guinney, Justin

AU - Wang, Tao

AU - Laajala, Teemu D.

AU - Winner, Kimberly Kanigel

AU - Bare, J. Christopher

AU - Neto, Elias Chaibub

AU - Khan, Suleiman A.

AU - Peddinti, Gopal

AU - Airola, Antti

AU - Pahikkala, Tapio

AU - Mirtti, Tuomas

AU - Yu, Thomas

AU - Bot, Brian M.

AU - Shen, Liji

AU - Abdallah, Kald

AU - Norman, Thea

AU - Friend, Stephen

AU - Stolovitzky, Gustavo

AU - Soule, Howard

AU - Sweeney, Christopher J.

AU - Ryan, Charles J.

AU - Scher, Howard I.

AU - Sartor, Oliver

AU - Xie, Yang

AU - Aittokallio, Tero

AU - Zhou, Fang Liz

AU - Costello, James C.

AU - Prostate Canc Challenge DREAM Comm

PY - 2017/1

Y1 - 2017/1

KW - SIPULEUCEL-T IMMUNOTHERAPY

KW - BIOMEDICAL-RESEARCH

KW - DOUBLE-BLIND

KW - PHASE-III

KW - CHEMOTHERAPY

KW - DOCETAXEL

KW - PREDNISONE

KW - PLACEBO

KW - MEN

KW - ENZALUTAMIDE

KW - 3122 Cancers

U2 - 10.1016/S1470-2045(16)30560-5

DO - 10.1016/S1470-2045(16)30560-5

M3 - Article

SN - 1470-2045

VL - 18

SP - 132

EP - 142

JO - Lancet Oncology

JF - Lancet Oncology

IS - 1

ER -