Pro-inflammatory M1 macrophages promote Osteogenesis by mesenchymal stem cells via the COX-2-prostaglandin E2 pathway

Laura Y. Lu, Florence Loi, Karthik Nathan, Tzu-hua Lin, Jukka Pajarinen, Emmanuel Gibon, Akira Nabeshima, Luis Cordova, Eemeli Jamsen, Zhenyu Yao, Stuart B. Goodman

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalJournal of Orthopaedic Research
Volume35
Issue number11
Pages (from-to)2378-2385
Number of pages8
ISSN0736-0266
DOIs
Publication statusPublished - Nov 2017
MoE publication typeA1 Journal article-refereed

Fields of Science

  • polarized macrophages
  • mesenchymal stem cells
  • osteogenesis
  • fracture healing
  • NONSTEROIDAL ANTIINFLAMMATORY DRUGS
  • SPINAL-FUSION
  • DOWN-REGULATION
  • BONE
  • CYCLOOXYGENASE-2
  • DIFFERENTIATION
  • POLARIZATION
  • INDUCTION
  • COX-2
  • MICE
  • 3121 General medicine, internal medicine and other clinical medicine
  • 3126 Surgery, anesthesiology, intensive care, radiology

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