Profiling persistent tubercule bacilli from patient sputa during therapy predicts early drug efficacy

Isobella Honeyborne, Timothy D. McHugh, Iitu Kuittinen, Anna Cichonska, Dimitrios Evangelopoulos, Katharina Ronacher, Paul D. van Helden, Stephen H. Gillespie, Delmiro Fernandez-Reyes, Gerhard Walzl, Juho Rousu, Philip D. Butcher, Simon J. Waddell

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
Article number68
JournalBMC Medicine
Volume14
Number of pages13
ISSN1741-7015
DOIs
Publication statusPublished - 7 Apr 2016
MoE publication typeA1 Journal article-refereed

Fields of Science

  • Mycobacterium tuberculosis
  • Sputum
  • Transcriptional profiling
  • Predictive biomarker
  • Persistent infection
  • GENE-EXPRESSION DATA
  • MYCOBACTERIUM-TUBERCULOSIS
  • TRANSCRIPTIONAL ADAPTATION
  • PULMONARY TUBERCULOSIS
  • CULTURE CONVERSION
  • MACROPHAGES
  • METABOLISM
  • SELECTION
  • TIME
  • POPULATIONS
  • 3111 Biomedicine

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