Prolyl 4-hydroxylase subunit alpha 1 (P4HA1) is a biomarker of poor prognosis in primary melanomas and its depletion inhibits melanoma cell invasion and disrupts tumor blood vessel walls

Johanna Eriksson; Vadim Le Joncour; Tiina Jahkola; Susanna Juteau; Pirjo Laakkonen; Olli Saksela; Erkki Hölttä

doi:10.1002/1878-0261.12649

Prolyl 4-hydroxylase subunit alpha 1 (P4HA1) is a biomarker of poor prognosis in primary melanomas and its depletion inhibits melanoma cell invasion and disrupts tumor blood vessel walls

Johanna Eriksson, Vadim Le Joncour, Tiina Jahkola, Susanna Juteau, Pirjo Laakkonen, Olli Saksela, Erkki Hölttä

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	Molecular oncology
Volume	14
Issue number	4
Pages (from-to)	742-762
Number of pages	21
ISSN	1574-7891
DOIs	https://doi.org/10.1002/1878-0261.12649
Publication status	Published - Apr 2020
MoE publication type	A1 Journal article-refereed

Fields of Science

3122 Cancers
melanoma
invasion
prognosis
P4HA1
CTHRC1
DECARBOXYLASE
COLLAGEN
DEATH
RHOC
CANCER
HYPOXIA SIGNATURES
GROWTH
EXPRESSION

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1878-0261.12649Accepted author manuscript, 31.2 MBLicence: CC BY

Cite this

@article{ad8d3dc7a6f54b2da81ca5ae36a2b33e,

title = "Prolyl 4-hydroxylase subunit alpha 1 (P4HA1) is a biomarker of poor prognosis in primary melanomas and its depletion inhibits melanoma cell invasion and disrupts tumor blood vessel walls",

keywords = "3122 Cancers, melanoma, invasion, prognosis, P4HA1, CTHRC1, DECARBOXYLASE, COLLAGEN, DEATH, RHOC, CANCER, HYPOXIA SIGNATURES, GROWTH, EXPRESSION",

author = "Johanna Eriksson and {Le Joncour}, Vadim and Tiina Jahkola and Susanna Juteau and Pirjo Laakkonen and Olli Saksela and Erkki H{\"o}ltt{\"a}",

year = "2020",

month = apr,

doi = "10.1002/1878-0261.12649",

language = "English",

volume = "14",

pages = "742--762",

journal = "Molecular oncology",

issn = "1574-7891",

publisher = "Wiley",

number = "4",

}

Eriksson, J , Le Joncour, V , Jahkola, T , Juteau, S , Laakkonen, P , Saksela, O & Hölttä, E 2020, 'Prolyl 4-hydroxylase subunit alpha 1 (P4HA1) is a biomarker of poor prognosis in primary melanomas and its depletion inhibits melanoma cell invasion and disrupts tumor blood vessel walls', Molecular oncology, vol. 14, no. 4, pp. 742-762. https://doi.org/10.1002/1878-0261.12649

Prolyl 4-hydroxylase subunit alpha 1 (P4HA1) is a biomarker of poor prognosis in primary melanomas and its depletion inhibits melanoma cell invasion and disrupts tumor blood vessel walls. / Eriksson, Johanna ; Le Joncour, Vadim ; Jahkola, Tiina et al.

In: Molecular oncology, Vol. 14, No. 4, 04.2020, p. 742-762.

Research output: Contribution to journal › Article › Scientific › peer-review

TY - JOUR

T1 - Prolyl 4-hydroxylase subunit alpha 1 (P4HA1) is a biomarker of poor prognosis in primary melanomas and its depletion inhibits melanoma cell invasion and disrupts tumor blood vessel walls

AU - Eriksson, Johanna

AU - Le Joncour, Vadim

AU - Jahkola, Tiina

AU - Juteau, Susanna

AU - Laakkonen, Pirjo

AU - Saksela, Olli

AU - Hölttä, Erkki

PY - 2020/4

Y1 - 2020/4

KW - 3122 Cancers

KW - melanoma

KW - invasion

KW - prognosis

KW - P4HA1

KW - CTHRC1

KW - DECARBOXYLASE

KW - COLLAGEN

KW - DEATH

KW - RHOC

KW - CANCER

KW - HYPOXIA SIGNATURES

KW - GROWTH

KW - EXPRESSION

U2 - 10.1002/1878-0261.12649

DO - 10.1002/1878-0261.12649

M3 - Article

VL - 14

SP - 742

EP - 762

JO - Molecular oncology

JF - Molecular oncology

SN - 1574-7891

IS - 4

ER -