PSEN1ΔE9, APPswe, and APOE4 Confer Disparate Phenotypes in Human iPSC-Derived Microglia

Henna Konttinen, Mauricio e Castro Cabral-da-Silva, Sohvi Ohtonen, Sara Wojciechowski, Anastasia Shakirzyanova, Simone Caligola, Rosalba Giugno, Yevheniia Ishchenko, Damián Hernández, Mohammad Feroze Fazaludeen, Shaila Eamen, Mireia Gómez Budia, Ilkka Fagerlund, Flavia Scoyni, Paula Korhonen, Nadine Huber, Annakaisa Haapasalo, Alex W. Hewitt, James Vickers, Grady C. SmithMinna Oksanen, Caroline Graff, Katja M. Kanninen, Sarka Lehtonen, Nicholas Propson, Michael P. Schwartz, Alice Pébay, Jari Koistinaho, Lezanne Ooi, Tarja Malm

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalStem cell reports
Volume13
Issue number4
Pages (from-to)669-683
Number of pages15
ISSN2213-6711
DOIs
Publication statusPublished - 8 Oct 2019
MoE publication typeA1 Journal article-refereed

Fields of Science

  • Alzheimer disease
  • iPSC
  • microglia
  • phagocytosis
  • mitochondria
  • metabolism
  • PLURIPOTENT STEM-CELLS
  • ALZHEIMERS-DISEASE
  • PRECURSOR PROTEIN
  • BETA
  • DIFFERENTIATION
  • MODEL
  • HEMATOPOIESIS
  • PRESENILIN-1
  • MACROPHAGES
  • ACTIVATION
  • 1182 Biochemistry, cell and molecular biology
  • 3111 Biomedicine

Cite this