PTPRA Phosphatase Regulates GDNF-Dependent RET Signaling and Inhibits the RET Mutant MEN2A Oncogenic Potential

Leena Yadav; Elina Pietilä; Tiina Öhman; Xiaonan Liu; Arun K. Mahato; Yulia Sidorova; Kaisa Lehti; Mart Saarma; Markku Varjosalo

doi:10.1016/j.isci.2020.100871

PTPRA Phosphatase Regulates GDNF-Dependent RET Signaling and Inhibits the RET Mutant MEN2A Oncogenic Potential

Leena Yadav, Elina Pietilä, Tiina Öhman, Xiaonan Liu, Arun K. Mahato, Yulia Sidorova, Kaisa Lehti, Mart Saarma, Markku Varjosalo

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Article number	100871
Journal	iScience
Volume	23
Issue number	2
Number of pages	34
ISSN	2589-0042
DOIs	https://doi.org/10.1016/j.isci.2020.100871
Publication status	Published - 21 Feb 2020
MoE publication type	A1 Journal article-refereed

Fields of Science

PROTEIN-TYROSINE-PHOSPHATASE
RPTP-ALPHA
CATALYTIC DOMAINS
BINDING-SITE
RECEPTOR
ACTIVATION
PROTOONCOGENE
KINASE
PHOSPHORYLATION
IDENTIFICATION
1182 Biochemistry, cell and molecular biology

Access to Document

10.1016/j.isci.2020.100871

PTPRA phosphatase regulates GDNF-dependent RET signaling and inhibits the RET mutant MEN2A oncogenic potentialAccepted author manuscript, 3.72 MBLicence: CC BY-NC-ND
PIIS2589004220300559Final published version, 8.02 MBLicence: CC BY-NC-ND

Cite this

@article{c180e922a47247ffa750189f41392f9e,

title = "PTPRA Phosphatase Regulates GDNF-Dependent RET Signaling and Inhibits the RET Mutant MEN2A Oncogenic Potential",

keywords = "PROTEIN-TYROSINE-PHOSPHATASE, RPTP-ALPHA, CATALYTIC DOMAINS, BINDING-SITE, RECEPTOR, ACTIVATION, PROTOONCOGENE, KINASE, PHOSPHORYLATION, IDENTIFICATION, 1182 Biochemistry, cell and molecular biology",

author = "Leena Yadav and Elina Pietil{\"a} and Tiina {\"O}hman and Xiaonan Liu and Mahato, {Arun K.} and Yulia Sidorova and Kaisa Lehti and Mart Saarma and Markku Varjosalo",

year = "2020",

month = feb,

day = "21",

doi = "10.1016/j.isci.2020.100871",

language = "English",

volume = "23",

journal = "iScience",

issn = "2589-0042",

publisher = "Cell Press Elsevier Inc.",

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TY - JOUR

T1 - PTPRA Phosphatase Regulates GDNF-Dependent RET Signaling and Inhibits the RET Mutant MEN2A Oncogenic Potential

AU - Yadav, Leena

AU - Pietilä, Elina

AU - Öhman, Tiina

AU - Liu, Xiaonan

AU - Mahato, Arun K.

AU - Sidorova, Yulia

AU - Lehti, Kaisa

AU - Saarma, Mart

AU - Varjosalo, Markku

PY - 2020/2/21

Y1 - 2020/2/21

KW - PROTEIN-TYROSINE-PHOSPHATASE

KW - RPTP-ALPHA

KW - CATALYTIC DOMAINS

KW - BINDING-SITE

KW - RECEPTOR

KW - ACTIVATION

KW - PROTOONCOGENE

KW - KINASE

KW - PHOSPHORYLATION

KW - IDENTIFICATION

KW - 1182 Biochemistry, cell and molecular biology

U2 - 10.1016/j.isci.2020.100871

DO - 10.1016/j.isci.2020.100871

M3 - Article

VL - 23

JO - iScience

JF - iScience

SN - 2589-0042

IS - 2

M1 - 100871

ER -