QuantISH: RNA in situ hybridization image analysis framework for quantifying cell type-specific target RNA expression and variability

Sanaz Jamalzadeh; Antti Häkkinen; Noora Andersson; Kaisa Huhtinen; Anna Laury; Sakari Hietanen; Johanna Hynninen; Jaana Oikkonen; Olli Carpen; Anni Virtanen; Sampsa Hautaniemi

doi:10.1038/s41374-022-00743-5

QuantISH: RNA in situ hybridization image analysis framework for quantifying cell type-specific target RNA expression and variability

Sanaz Jamalzadeh, Antti Häkkinen, Noora Andersson, Kaisa Huhtinen, Anna Laury, Sakari Hietanen, Johanna Hynninen, Jaana Oikkonen, Olli Carpen, Anni Virtanen, Sampsa Hautaniemi

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	Laboratory Investigation
Volume	102
Issue number	7
Pages (from-to)	753-761
Number of pages	9
ISSN	0023-6837
DOIs	https://doi.org/10.1038/s41374-022-00743-5
Publication status	Published - Jul 2022
MoE publication type	A1 Journal article-refereed

Fields of Science

GENE AMPLIFICATION
CANCER
3111 Biomedicine

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10.1038/s41374-022-00743-5Licence: CC BY

s41374-022-00743-5Final published version, 2.79 MBLicence: CC BY

Cite this

Jamalzadeh, S., Häkkinen, A., Andersson, N., Huhtinen, K., Laury, A., Hietanen, S., Hynninen, J., Oikkonen, J., Carpen, O., Virtanen, A., & Hautaniemi, S. (2022). QuantISH: RNA in situ hybridization image analysis framework for quantifying cell type-specific target RNA expression and variability. Laboratory Investigation, 102(7), 753-761. https://doi.org/10.1038/s41374-022-00743-5

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keywords = "GENE AMPLIFICATION, CANCER, 3111 Biomedicine",

author = "Sanaz Jamalzadeh and Antti H{\"a}kkinen and Noora Andersson and Kaisa Huhtinen and Anna Laury and Sakari Hietanen and Johanna Hynninen and Jaana Oikkonen and Olli Carpen and Anni Virtanen and Sampsa Hautaniemi",

year = "2022",

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doi = "10.1038/s41374-022-00743-5",

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Jamalzadeh, S , Häkkinen, A , Andersson, N, Huhtinen, K, Laury, A, Hietanen, S, Hynninen, J, Oikkonen, J , Carpen, O , Virtanen, A & Hautaniemi, S 2022, 'QuantISH: RNA in situ hybridization image analysis framework for quantifying cell type-specific target RNA expression and variability', Laboratory Investigation, vol. 102, no. 7, pp. 753-761. https://doi.org/10.1038/s41374-022-00743-5

TY - JOUR

T1 - QuantISH

T2 - RNA in situ hybridization image analysis framework for quantifying cell type-specific target RNA expression and variability

AU - Jamalzadeh, Sanaz

AU - Häkkinen, Antti

AU - Andersson, Noora

AU - Huhtinen, Kaisa

AU - Laury, Anna

AU - Hietanen, Sakari

AU - Hynninen, Johanna

AU - Oikkonen, Jaana

AU - Carpen, Olli

AU - Virtanen, Anni

AU - Hautaniemi, Sampsa

PY - 2022/7

Y1 - 2022/7

KW - GENE AMPLIFICATION

KW - CANCER

KW - 3111 Biomedicine

U2 - 10.1038/s41374-022-00743-5

DO - 10.1038/s41374-022-00743-5

M3 - Article

SN - 0023-6837

VL - 102

SP - 753

EP - 761

JO - Laboratory Investigation

JF - Laboratory Investigation

IS - 7

ER -