Rational Polypharmacology: Systematically Identifying and Engaging Multiple Drug Targets To Promote Axon Growth

Hassan Al-Ali, Do-Hun Lee, Matt C. Danzi, Houssam Nassif, Prson Gautam, Krister Wennerberg, Bill Zuercher, David H. Drewry, Jae K. Lee, Vance P. Lemmon, John L. Bixby

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalACS Chemical Biology
Volume10
Issue number8
Pages (from-to)1939-1951
Number of pages13
ISSN1554-8929
DOIs
Publication statusPublished - Aug 2015
MoE publication typeA1 Journal article-refereed

Fields of Science

  • CHONDROITIN SULFATE PROTEOGLYCANS
  • PROTEIN-KINASE INHIBITORS
  • NEURITE OUTGROWTH
  • BREAST-CANCER
  • BET FAMILY
  • REGENERATION
  • KINOME
  • DISCOVERY
  • CNS
  • NEURONS
  • 3111 Biomedicine

Cite this

Al-Ali, Hassan ; Lee, Do-Hun ; Danzi, Matt C. ; Nassif, Houssam ; Gautam, Prson ; Wennerberg, Krister ; Zuercher, Bill ; Drewry, David H. ; Lee, Jae K. ; Lemmon, Vance P. ; Bixby, John L. / Rational Polypharmacology : Systematically Identifying and Engaging Multiple Drug Targets To Promote Axon Growth. In: ACS Chemical Biology. 2015 ; Vol. 10, No. 8. pp. 1939-1951.
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title = "Rational Polypharmacology: Systematically Identifying and Engaging Multiple Drug Targets To Promote Axon Growth",
keywords = "CHONDROITIN SULFATE PROTEOGLYCANS, PROTEIN-KINASE INHIBITORS, NEURITE OUTGROWTH, BREAST-CANCER, BET FAMILY, REGENERATION, KINOME, DISCOVERY, CNS, NEURONS, 3111 Biomedicine",
author = "Hassan Al-Ali and Do-Hun Lee and Danzi, {Matt C.} and Houssam Nassif and Prson Gautam and Krister Wennerberg and Bill Zuercher and Drewry, {David H.} and Lee, {Jae K.} and Lemmon, {Vance P.} and Bixby, {John L.}",
year = "2015",
month = "8",
doi = "10.1021/acschembio.5b00289",
language = "English",
volume = "10",
pages = "1939--1951",
journal = "ACS Chemical Biology",
issn = "1554-8929",
publisher = "American Chemical Society",
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}

Al-Ali, H, Lee, D-H, Danzi, MC, Nassif, H, Gautam, P, Wennerberg, K, Zuercher, B, Drewry, DH, Lee, JK, Lemmon, VP & Bixby, JL 2015, 'Rational Polypharmacology: Systematically Identifying and Engaging Multiple Drug Targets To Promote Axon Growth' ACS Chemical Biology, vol. 10, no. 8, pp. 1939-1951. https://doi.org/10.1021/acschembio.5b00289

Rational Polypharmacology : Systematically Identifying and Engaging Multiple Drug Targets To Promote Axon Growth. / Al-Ali, Hassan; Lee, Do-Hun; Danzi, Matt C.; Nassif, Houssam; Gautam, Prson; Wennerberg, Krister; Zuercher, Bill; Drewry, David H.; Lee, Jae K.; Lemmon, Vance P.; Bixby, John L.

In: ACS Chemical Biology, Vol. 10, No. 8, 08.2015, p. 1939-1951.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Rational Polypharmacology

T2 - Systematically Identifying and Engaging Multiple Drug Targets To Promote Axon Growth

AU - Al-Ali, Hassan

AU - Lee, Do-Hun

AU - Danzi, Matt C.

AU - Nassif, Houssam

AU - Gautam, Prson

AU - Wennerberg, Krister

AU - Zuercher, Bill

AU - Drewry, David H.

AU - Lee, Jae K.

AU - Lemmon, Vance P.

AU - Bixby, John L.

PY - 2015/8

Y1 - 2015/8

KW - CHONDROITIN SULFATE PROTEOGLYCANS

KW - PROTEIN-KINASE INHIBITORS

KW - NEURITE OUTGROWTH

KW - BREAST-CANCER

KW - BET FAMILY

KW - REGENERATION

KW - KINOME

KW - DISCOVERY

KW - CNS

KW - NEURONS

KW - 3111 Biomedicine

U2 - 10.1021/acschembio.5b00289

DO - 10.1021/acschembio.5b00289

M3 - Article

VL - 10

SP - 1939

EP - 1951

JO - ACS Chemical Biology

JF - ACS Chemical Biology

SN - 1554-8929

IS - 8

ER -