Recent trends on the development of systems for cancer diagnosis and treatment by microfluidic technology

Ana Cristina Q. Silva, Carla Vilela, Hélder A. Santos, Armando J. D. Silvestre, Carmen S. R. Freire

Research output: Contribution to journalReview Articlepeer-review

Abstract

Cancer is the second leading cause of non-accidental death in the world, accounting for roughly 9.6 million deaths in 2018. In the latter years, research in this domain has grown exponentially, as a way to provide deep insights into this malignancy, but also new tools for early diagnosis and efficient personalized treatment options. Microfluidic lab-on-a-chip technology has demonstrated a high potential on the design of new methodologies for cancer diagnosis, treatment and disease follow-up. Here, we present a detailed review on the application of the microfluidic platforms for the detection and separation of tumour cells from blood (liquid biopsy) and the development of new drug delivery systems for cancer conquering.
Original languageEnglish
Article number100450
JournalApplied materials today
Volume18
Number of pages15
ISSN2352-9407
DOIs
Publication statusPublished - Mar 2020
MoE publication typeA2 Review article in a scientific journal

Fields of Science

  • CHIP
  • CIRCULATING TUMOR-CELLS
  • Cancer diagnosis
  • Cancer therapy
  • DRUG-DELIVERY SYSTEMS
  • Drug delivery systems
  • GENEXOL-PM
  • LABEL-FREE ISOLATION
  • Lab-on-a-chip
  • Microfluidic technology
  • ONE-STEP FABRICATION
  • PHASE-I
  • PLATFORM
  • POLYMERIC NANOPARTICLES
  • RECENT PROGRESS
  • 317 Pharmacy
  • 221 Nano-technology
  • 318 Medical biotechnology

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