Reduced level of docosahexaenoic acid shifts GPCR neuroreceptors to less ordered membrane regions

Matti Javanainen; Giray Enkavi; Ramon Guixa-Gonzalez; Waldemar Kulig; Hector Martinez-Seara; Ilya Levental; Ilpo Vattulainen

doi:10.1371/journal.pcbi.1007033

Reduced level of docosahexaenoic acid shifts GPCR neuroreceptors to less ordered membrane regions

Matti Javanainen, Giray Enkavi, Ramon Guixa-Gonzalez, Waldemar Kulig, Hector Martinez-Seara, Ilya Levental, Ilpo Vattulainen

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Article number	1007033
Journal	PLoS Computational Biology
Volume	15
Issue number	5
Number of pages	16
ISSN	1553-734X
DOIs	https://doi.org/10.1371/journal.pcbi.1007033
Publication status	Published - May 2019
MoE publication type	A1 Journal article-refereed

Fields of Science

LIPID-PROTEIN INTERACTIONS
A(2A) ADENOSINE RECEPTOR
SURFACE-ROUGHNESS
CRYSTAL-STRUCTURE
FORCE-FIELD
PHOSPHOLIPID-COMPOSITION
GLUCOSE-TRANSPORT
COUPLED RECEPTORS
PHASE-DIAGRAM
FATTY-ACIDS
1182 Biochemistry, cell and molecular biology
114 Physical sciences

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10.1371/journal.pcbi.1007033Licence: CC BY

journal.pcbi.1007033Final published version, 2.64 MBLicence: CC BY

Cite this

@article{a4a8432bf49a431a8309028ff3c8d703,

title = "Reduced level of docosahexaenoic acid shifts GPCR neuroreceptors to less ordered membrane regions",

keywords = "LIPID-PROTEIN INTERACTIONS, A(2A) ADENOSINE RECEPTOR, SURFACE-ROUGHNESS, CRYSTAL-STRUCTURE, FORCE-FIELD, PHOSPHOLIPID-COMPOSITION, GLUCOSE-TRANSPORT, COUPLED RECEPTORS, PHASE-DIAGRAM, FATTY-ACIDS, 1182 Biochemistry, cell and molecular biology, 114 Physical sciences",

author = "Matti Javanainen and Giray Enkavi and Ramon Guixa-Gonzalez and Waldemar Kulig and Hector Martinez-Seara and Ilya Levental and Ilpo Vattulainen",

year = "2019",

month = may,

doi = "10.1371/journal.pcbi.1007033",

language = "English",

volume = "15",

journal = "PLoS Computational Biology",

issn = "1553-734X",

publisher = "PUBLIC LIBRARY OF SCIENCE",

number = "5",

}

Reduced level of docosahexaenoic acid shifts GPCR neuroreceptors to less ordered membrane regions. / Javanainen, Matti ; Enkavi, Giray; Guixa-Gonzalez, Ramon; Kulig, Waldemar; Martinez-Seara, Hector; Levental, Ilya; Vattulainen, Ilpo.

In: PLoS Computational Biology, Vol. 15, No. 5, 1007033, 05.2019.

Research output: Contribution to journal › Article › Scientific › peer-review

TY - JOUR

T1 - Reduced level of docosahexaenoic acid shifts GPCR neuroreceptors to less ordered membrane regions

AU - Javanainen, Matti

AU - Enkavi, Giray

AU - Guixa-Gonzalez, Ramon

AU - Kulig, Waldemar

AU - Martinez-Seara, Hector

AU - Levental, Ilya

AU - Vattulainen, Ilpo

PY - 2019/5

Y1 - 2019/5

KW - LIPID-PROTEIN INTERACTIONS

KW - A(2A) ADENOSINE RECEPTOR

KW - SURFACE-ROUGHNESS

KW - CRYSTAL-STRUCTURE

KW - FORCE-FIELD

KW - PHOSPHOLIPID-COMPOSITION

KW - GLUCOSE-TRANSPORT

KW - COUPLED RECEPTORS

KW - PHASE-DIAGRAM

KW - FATTY-ACIDS

KW - 1182 Biochemistry, cell and molecular biology

KW - 114 Physical sciences

U2 - 10.1371/journal.pcbi.1007033

DO - 10.1371/journal.pcbi.1007033

M3 - Article

VL - 15

JO - PLoS Computational Biology

JF - PLoS Computational Biology

SN - 1553-734X

IS - 5

M1 - 1007033

ER -