Reduced MAD2 levels dampen the apoptotic response to non-exchange sex chromosomes and lead to sperm aneuploidy

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalDevelopment
Volume144
Issue number11
Pages (from-to)1988-1996
Number of pages9
ISSN0950-1991
DOIs
Publication statusPublished - 1 Jun 2017
MoE publication typeA1 Journal article-refereed

Fields of Science

  • Apoptosis
  • Aneuploidy
  • Sex chromosomes
  • Meiosis
  • Spindle assembly checkpoint
  • MAD2
  • Mouse
  • SPINDLE ASSEMBLY CHECKPOINT
  • DOUBLE-STRAND BREAKS
  • SACCHAROMYCES-CEREVISIAE
  • PSEUDOAUTOSOMAL REGION
  • BUDDING YEAST
  • PROTEIN MAD2
  • MEIOSIS-I
  • ABERRANT RECOMBINATION
  • MEIOTIC RECOMBINATION
  • MISMATCH REPAIR
  • 3111 Biomedicine
  • 1184 Genetics, developmental biology, physiology

Cite this

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title = "Reduced MAD2 levels dampen the apoptotic response to non-exchange sex chromosomes and lead to sperm aneuploidy",
keywords = "Apoptosis, Aneuploidy, Sex chromosomes, Meiosis, Spindle assembly checkpoint, MAD2, Mouse, SPINDLE ASSEMBLY CHECKPOINT, DOUBLE-STRAND BREAKS, SACCHAROMYCES-CEREVISIAE, PSEUDOAUTOSOMAL REGION, BUDDING YEAST, PROTEIN MAD2, MEIOSIS-I, ABERRANT RECOMBINATION, MEIOTIC RECOMBINATION, MISMATCH REPAIR, 3111 Biomedicine, 1184 Genetics, developmental biology, physiology",
author = "Imrul Faisal and Liisa Kauppi",
year = "2017",
month = "6",
day = "1",
doi = "10.1242/dev.149492",
language = "English",
volume = "144",
pages = "1988--1996",
journal = "Development",
issn = "0950-1991",
publisher = "Company of Biologists Ltd",
number = "11",

}

Reduced MAD2 levels dampen the apoptotic response to non-exchange sex chromosomes and lead to sperm aneuploidy. / Faisal, Imrul; Kauppi, Liisa.

In: Development, Vol. 144, No. 11, 01.06.2017, p. 1988-1996.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Reduced MAD2 levels dampen the apoptotic response to non-exchange sex chromosomes and lead to sperm aneuploidy

AU - Faisal, Imrul

AU - Kauppi, Liisa

PY - 2017/6/1

Y1 - 2017/6/1

KW - Apoptosis

KW - Aneuploidy

KW - Sex chromosomes

KW - Meiosis

KW - Spindle assembly checkpoint

KW - MAD2

KW - Mouse

KW - SPINDLE ASSEMBLY CHECKPOINT

KW - DOUBLE-STRAND BREAKS

KW - SACCHAROMYCES-CEREVISIAE

KW - PSEUDOAUTOSOMAL REGION

KW - BUDDING YEAST

KW - PROTEIN MAD2

KW - MEIOSIS-I

KW - ABERRANT RECOMBINATION

KW - MEIOTIC RECOMBINATION

KW - MISMATCH REPAIR

KW - 3111 Biomedicine

KW - 1184 Genetics, developmental biology, physiology

U2 - 10.1242/dev.149492

DO - 10.1242/dev.149492

M3 - Article

VL - 144

SP - 1988

EP - 1996

JO - Development

JF - Development

SN - 0950-1991

IS - 11

ER -