Regularized Machine Learning in the Genetic Prediction of Complex Traits

Sebastian Okser, Tapio Pahikkala, Antti Airola, Tapio Salakoski, Samuli Ripatti, Tero Aittokallio

Research output: Contribution to journalReview ArticleScientificpeer-review

Original languageEnglish
Article number1004754
JournalPLoS Genetics
Volume10
Issue number11
Number of pages9
ISSN1553-7390
DOIs
Publication statusPublished - Nov 2014
MoE publication typeA2 Review article in a scientific journal

Fields of Science

  • GENOME-WIDE ASSOCIATION
  • RISK PREDICTION
  • MISSING HERITABILITY
  • VARIABLE SELECTION
  • RANDOM FOREST
  • POPULATION STRATIFICATION
  • LINKAGE DISEQUILIBRIUM
  • SPARSE REGRESSION
  • HUMAN-DISEASE
  • MIXED-MODEL
  • 3111 Biomedicine

Cite this

Okser, Sebastian ; Pahikkala, Tapio ; Airola, Antti ; Salakoski, Tapio ; Ripatti, Samuli ; Aittokallio, Tero. / Regularized Machine Learning in the Genetic Prediction of Complex Traits. In: PLoS Genetics. 2014 ; Vol. 10, No. 11.
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title = "Regularized Machine Learning in the Genetic Prediction of Complex Traits",
keywords = "GENOME-WIDE ASSOCIATION, RISK PREDICTION, MISSING HERITABILITY, VARIABLE SELECTION, RANDOM FOREST, POPULATION STRATIFICATION, LINKAGE DISEQUILIBRIUM, SPARSE REGRESSION, HUMAN-DISEASE, MIXED-MODEL, 3111 Biomedicine",
author = "Sebastian Okser and Tapio Pahikkala and Antti Airola and Tapio Salakoski and Samuli Ripatti and Tero Aittokallio",
year = "2014",
month = "11",
doi = "10.1371/journal.pgen.1004754",
language = "English",
volume = "10",
journal = "PLoS Genetics",
issn = "1553-7390",
publisher = "PUBLIC LIBRARY OF SCIENCE",
number = "11",

}

Regularized Machine Learning in the Genetic Prediction of Complex Traits. / Okser, Sebastian; Pahikkala, Tapio; Airola, Antti; Salakoski, Tapio; Ripatti, Samuli; Aittokallio, Tero.

In: PLoS Genetics, Vol. 10, No. 11, 1004754, 11.2014.

Research output: Contribution to journalReview ArticleScientificpeer-review

TY - JOUR

T1 - Regularized Machine Learning in the Genetic Prediction of Complex Traits

AU - Okser, Sebastian

AU - Pahikkala, Tapio

AU - Airola, Antti

AU - Salakoski, Tapio

AU - Ripatti, Samuli

AU - Aittokallio, Tero

PY - 2014/11

Y1 - 2014/11

KW - GENOME-WIDE ASSOCIATION

KW - RISK PREDICTION

KW - MISSING HERITABILITY

KW - VARIABLE SELECTION

KW - RANDOM FOREST

KW - POPULATION STRATIFICATION

KW - LINKAGE DISEQUILIBRIUM

KW - SPARSE REGRESSION

KW - HUMAN-DISEASE

KW - MIXED-MODEL

KW - 3111 Biomedicine

U2 - 10.1371/journal.pgen.1004754

DO - 10.1371/journal.pgen.1004754

M3 - Review Article

VL - 10

JO - PLoS Genetics

JF - PLoS Genetics

SN - 1553-7390

IS - 11

M1 - 1004754

ER -