Relationship of Edoxaban Plasma Concentration and Blood Coagulation in Healthy Volunteers Using Standard Laboratory Tests and Viscoelastic Analysis

Martina Havrdova; Teijo I. Saari; Jouko Jalonen; Marko Peltoniemi; Mika Kurkela; Tero Vahlberg; Anri Tienhaara; Janne T. Backman; Klaus T. Olkkola; Alexey Schramko

doi:10.1002/jcph.1758

Relationship of Edoxaban Plasma Concentration and Blood Coagulation in Healthy Volunteers Using Standard Laboratory Tests and Viscoelastic Analysis

Martina Havrdova, Teijo I. Saari, Jouko Jalonen, Marko Peltoniemi, Mika Kurkela, Tero Vahlberg, Anri Tienhaara, Janne T. Backman, Klaus T. Olkkola, Alexey Schramko

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	Journal of Clinical Pharmacology
Volume	61
Issue number	4
Pages (from-to)	522-530
Number of pages	9
ISSN	0091-2700
DOIs	https://doi.org/10.1002/jcph.1758
Publication status	Published - Apr 2021
MoE publication type	A1 Journal article-refereed

Fields of Science

blood coagulation tests
drug monitoring
factor Xa inhibitors
healthy volunteers
thrombelastography
DIRECT ORAL ANTICOAGULANTS
MANAGEMENT
TEG
317 Pharmacy

Access to Document

10.1002/jcph.1758

Cite this

Havrdova, M., Saari, T. I., Jalonen, J., Peltoniemi, M., Kurkela, M., Vahlberg, T., Tienhaara, A., Backman, J. T., Olkkola, K. T., & Schramko, A. (2021). Relationship of Edoxaban Plasma Concentration and Blood Coagulation in Healthy Volunteers Using Standard Laboratory Tests and Viscoelastic Analysis. Journal of Clinical Pharmacology, 61(4), 522-530. https://doi.org/10.1002/jcph.1758

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title = "Relationship of Edoxaban Plasma Concentration and Blood Coagulation in Healthy Volunteers Using Standard Laboratory Tests and Viscoelastic Analysis",

keywords = "blood coagulation tests, drug monitoring, factor Xa inhibitors, healthy volunteers, thrombelastography, DIRECT ORAL ANTICOAGULANTS, MANAGEMENT, TEG, 317 Pharmacy",

author = "Martina Havrdova and Saari, {Teijo I.} and Jouko Jalonen and Marko Peltoniemi and Mika Kurkela and Tero Vahlberg and Anri Tienhaara and Backman, {Janne T.} and Olkkola, {Klaus T.} and Alexey Schramko",

year = "2021",

month = apr,

doi = "10.1002/jcph.1758",

language = "English",

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pages = "522--530",

journal = "Journal of Clinical Pharmacology",

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Havrdova, M, Saari, TI, Jalonen, J, Peltoniemi, M, Kurkela, M, Vahlberg, T, Tienhaara, A, Backman, JT , Olkkola, KT & Schramko, A 2021, 'Relationship of Edoxaban Plasma Concentration and Blood Coagulation in Healthy Volunteers Using Standard Laboratory Tests and Viscoelastic Analysis', Journal of Clinical Pharmacology, vol. 61, no. 4, pp. 522-530. https://doi.org/10.1002/jcph.1758

TY - JOUR

T1 - Relationship of Edoxaban Plasma Concentration and Blood Coagulation in Healthy Volunteers Using Standard Laboratory Tests and Viscoelastic Analysis

AU - Havrdova, Martina

AU - Saari, Teijo I.

AU - Jalonen, Jouko

AU - Peltoniemi, Marko

AU - Kurkela, Mika

AU - Vahlberg, Tero

AU - Tienhaara, Anri

AU - Backman, Janne T.

AU - Olkkola, Klaus T.

AU - Schramko, Alexey

PY - 2021/4

Y1 - 2021/4

KW - blood coagulation tests

KW - drug monitoring

KW - factor Xa inhibitors

KW - healthy volunteers

KW - thrombelastography

KW - DIRECT ORAL ANTICOAGULANTS

KW - MANAGEMENT

KW - TEG

KW - 317 Pharmacy

U2 - 10.1002/jcph.1758

DO - 10.1002/jcph.1758

M3 - Article

SN - 0091-2700

VL - 61

SP - 522

EP - 530

JO - Journal of Clinical Pharmacology

JF - Journal of Clinical Pharmacology

IS - 4

ER -