Relevant biological interactions biomimicked by capillary electromigration techniques

Katriina Lipponen; Susanne K. Wiedmer; Marja Liisa Riekkola

doi:10.1016/j.jcoa.2021.100020

Relevant biological interactions biomimicked by capillary electromigration techniques

Katriina Lipponen, Susanne K. Wiedmer, Marja Liisa Riekkola

Research output: Contribution to journal › Review Article › peer-review

Abstract

The potential of using capillary electromigration techniques for biomimicking essential biological interactions is described. The most commonly used methodologies with their exploitation in calculations of kinetics and biomolecular interaction data are briefly discussed. Experimental approaches for bimolecular interactions with some selected examples, including lipoproteins, glycosaminoglycan, liposomes and some DNA or RNA interactions, are enlighted including the affinity constants for some selective important interactions. The review demonstrates that capillary electromigration techniques can be used as alternative biomimicking tools for the determination of important biological interactions. This review covers selected papers published in 2003-2021.

Original language	English
Article number	100020
Journal	Journal of Chromatography Open
Volume	1
ISSN	2772-3917
DOIs	https://doi.org/10.1016/j.jcoa.2021.100020
Publication status	Published - Nov 2021
MoE publication type	A2 Review article in a scientific journal

Bibliographical note

Publisher Copyright:
© 2021 The Authors

Fields of Science

affinity chromatography
affinity constants
biomolecular interactions
capillary electrochromatography
capillary electromigration techniques
kinetic capillary electrophoresis
116 Chemical sciences

Access to Document

10.1016/j.jcoa.2021.100020Licence: CC BY

1-s2.0-S2772391721000207-mainFinal published version, 2.66 MBLicence: CC BY

Cite this

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title = "Relevant biological interactions biomimicked by capillary electromigration techniques",

abstract = "The potential of using capillary electromigration techniques for biomimicking essential biological interactions is described. The most commonly used methodologies with their exploitation in calculations of kinetics and biomolecular interaction data are briefly discussed. Experimental approaches for bimolecular interactions with some selected examples, including lipoproteins, glycosaminoglycan, liposomes and some DNA or RNA interactions, are enlighted including the affinity constants for some selective important interactions. The review demonstrates that capillary electromigration techniques can be used as alternative biomimicking tools for the determination of important biological interactions. This review covers selected papers published in 2003-2021.",

keywords = "affinity chromatography, affinity constants, biomolecular interactions, capillary electrochromatography, capillary electromigration techniques, kinetic capillary electrophoresis, 116 Chemical sciences",

author = "Katriina Lipponen and Wiedmer, {Susanne K.} and Riekkola, {Marja Liisa}",

note = "Publisher Copyright: {\textcopyright} 2021 The Authors",

year = "2021",

month = nov,

doi = "10.1016/j.jcoa.2021.100020",

language = "English",

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journal = "Journal of Chromatography Open",

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TY - JOUR

T1 - Relevant biological interactions biomimicked by capillary electromigration techniques

AU - Lipponen, Katriina

AU - Wiedmer, Susanne K.

AU - Riekkola, Marja Liisa

PY - 2021/11

Y1 - 2021/11

N2 - The potential of using capillary electromigration techniques for biomimicking essential biological interactions is described. The most commonly used methodologies with their exploitation in calculations of kinetics and biomolecular interaction data are briefly discussed. Experimental approaches for bimolecular interactions with some selected examples, including lipoproteins, glycosaminoglycan, liposomes and some DNA or RNA interactions, are enlighted including the affinity constants for some selective important interactions. The review demonstrates that capillary electromigration techniques can be used as alternative biomimicking tools for the determination of important biological interactions. This review covers selected papers published in 2003-2021.

AB - The potential of using capillary electromigration techniques for biomimicking essential biological interactions is described. The most commonly used methodologies with their exploitation in calculations of kinetics and biomolecular interaction data are briefly discussed. Experimental approaches for bimolecular interactions with some selected examples, including lipoproteins, glycosaminoglycan, liposomes and some DNA or RNA interactions, are enlighted including the affinity constants for some selective important interactions. The review demonstrates that capillary electromigration techniques can be used as alternative biomimicking tools for the determination of important biological interactions. This review covers selected papers published in 2003-2021.

KW - affinity chromatography

KW - affinity constants

KW - biomolecular interactions

KW - capillary electrochromatography

KW - capillary electromigration techniques

KW - kinetic capillary electrophoresis

KW - 116 Chemical sciences

U2 - 10.1016/j.jcoa.2021.100020

DO - 10.1016/j.jcoa.2021.100020

M3 - Review Article

AN - SCOPUS:85141110676

SN - 2772-3917

VL - 1

JO - Journal of Chromatography Open

JF - Journal of Chromatography Open

M1 - 100020

ER -