RNA Interference-Guided Targeting of Hepatitis C Virus Replication with Antisense Locked Nucleic Acid-Based Oligonucleotides Containing 8-oxo-dG Modifications

Margit Mutso, Andrei Nikonov, Arno Pihlak, Eva Zusinaite, Liane Viru, Anastasia Selyutina, Tonu Reintamm, Merike Kelve, Mart Saarma, Mati Karelson, Andres Merits

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
Article number0128686
JournalPLoS One
Volume10
Issue number6
Number of pages25
ISSN1932-6203
DOIs
Publication statusPublished - 3 Jun 2015
MoE publication typeA1 Journal article-refereed

Fields of Science

  • RIBOSOME ENTRY SITE
  • GENE-EXPRESSION
  • SECONDARY STRUCTURE
  • MAMMALIAN-CELLS
  • RIBONUCLEASE-H
  • ORAL DELIVERY
  • DNA
  • INHIBITION
  • TRANSLATION
  • MICRORNA
  • 1183 Plant biology, microbiology, virology

Cite this

Mutso, Margit ; Nikonov, Andrei ; Pihlak, Arno ; Zusinaite, Eva ; Viru, Liane ; Selyutina, Anastasia ; Reintamm, Tonu ; Kelve, Merike ; Saarma, Mart ; Karelson, Mati ; Merits, Andres. / RNA Interference-Guided Targeting of Hepatitis C Virus Replication with Antisense Locked Nucleic Acid-Based Oligonucleotides Containing 8-oxo-dG Modifications. In: PLoS One. 2015 ; Vol. 10, No. 6.
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title = "RNA Interference-Guided Targeting of Hepatitis C Virus Replication with Antisense Locked Nucleic Acid-Based Oligonucleotides Containing 8-oxo-dG Modifications",
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author = "Margit Mutso and Andrei Nikonov and Arno Pihlak and Eva Zusinaite and Liane Viru and Anastasia Selyutina and Tonu Reintamm and Merike Kelve and Mart Saarma and Mati Karelson and Andres Merits",
year = "2015",
month = "6",
day = "3",
doi = "10.1371/journal.pone.0128686",
language = "English",
volume = "10",
journal = "PLoS One",
issn = "1932-6203",
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Mutso, M, Nikonov, A, Pihlak, A, Zusinaite, E, Viru, L, Selyutina, A, Reintamm, T, Kelve, M, Saarma, M, Karelson, M & Merits, A 2015, 'RNA Interference-Guided Targeting of Hepatitis C Virus Replication with Antisense Locked Nucleic Acid-Based Oligonucleotides Containing 8-oxo-dG Modifications', PLoS One, vol. 10, no. 6, 0128686. https://doi.org/10.1371/journal.pone.0128686

RNA Interference-Guided Targeting of Hepatitis C Virus Replication with Antisense Locked Nucleic Acid-Based Oligonucleotides Containing 8-oxo-dG Modifications. / Mutso, Margit; Nikonov, Andrei; Pihlak, Arno; Zusinaite, Eva; Viru, Liane; Selyutina, Anastasia; Reintamm, Tonu; Kelve, Merike; Saarma, Mart; Karelson, Mati; Merits, Andres.

In: PLoS One, Vol. 10, No. 6, 0128686, 03.06.2015.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - RNA Interference-Guided Targeting of Hepatitis C Virus Replication with Antisense Locked Nucleic Acid-Based Oligonucleotides Containing 8-oxo-dG Modifications

AU - Mutso, Margit

AU - Nikonov, Andrei

AU - Pihlak, Arno

AU - Zusinaite, Eva

AU - Viru, Liane

AU - Selyutina, Anastasia

AU - Reintamm, Tonu

AU - Kelve, Merike

AU - Saarma, Mart

AU - Karelson, Mati

AU - Merits, Andres

PY - 2015/6/3

Y1 - 2015/6/3

KW - RIBOSOME ENTRY SITE

KW - GENE-EXPRESSION

KW - SECONDARY STRUCTURE

KW - MAMMALIAN-CELLS

KW - RIBONUCLEASE-H

KW - ORAL DELIVERY

KW - DNA

KW - INHIBITION

KW - TRANSLATION

KW - MICRORNA

KW - 1183 Plant biology, microbiology, virology

U2 - 10.1371/journal.pone.0128686

DO - 10.1371/journal.pone.0128686

M3 - Article

VL - 10

JO - PLoS One

JF - PLoS One

SN - 1932-6203

IS - 6

M1 - 0128686

ER -