Role of Cytochrome P450 2C8 in Drug Metabolism and Interactions

Research output: Contribution to journalReview ArticleScientificpeer-review

Original languageEnglish
JournalPharmacological Reviews
Volume68
Issue number1
Pages (from-to)168-241
Number of pages74
ISSN0031-6997
DOIs
Publication statusPublished - Jan 2016
MoE publication typeA2 Review article in a scientific journal

Fields of Science

  • HUMAN LIVER-MICROSOMES
  • IN-VITRO METABOLISM
  • HMG-COA REDUCTASE
  • MECHANISM-BASED INACTIVATION
  • HUMAN HEPATIC MICROSOMES
  • BISPHOSPHONATE-RELATED OSTEONECROSIS
  • TIME-DEPENDENT INHIBITION
  • TANDEM MASS-SPECTROMETRY
  • SINGLE-NUCLEOTIDE POLYMORPHISMS
  • FLAVIN-CONTAINING MONOOXYGENASE
  • 3111 Biomedicine

Cite this

@article{a0b91fb029c648e3b3c5afa5dd4deda7,
title = "Role of Cytochrome P450 2C8 in Drug Metabolism and Interactions",
keywords = "HUMAN LIVER-MICROSOMES, IN-VITRO METABOLISM, HMG-COA REDUCTASE, MECHANISM-BASED INACTIVATION, HUMAN HEPATIC MICROSOMES, BISPHOSPHONATE-RELATED OSTEONECROSIS, TIME-DEPENDENT INHIBITION, TANDEM MASS-SPECTROMETRY, SINGLE-NUCLEOTIDE POLYMORPHISMS, FLAVIN-CONTAINING MONOOXYGENASE, 3111 Biomedicine",
author = "Backman, {Janne T.} and Filppula, {Anne M.} and Mikko Niemi and Neuvonen, {Pertti J.}",
year = "2016",
month = "1",
doi = "10.1124/pr.115.011411",
language = "English",
volume = "68",
pages = "168--241",
journal = "Pharmacological Reviews",
issn = "0031-6997",
publisher = "American Society for Pharmacology and Experimental Therapeutics",
number = "1",

}

Role of Cytochrome P450 2C8 in Drug Metabolism and Interactions. / Backman, Janne T.; Filppula, Anne M.; Niemi, Mikko; Neuvonen, Pertti J.

In: Pharmacological Reviews, Vol. 68, No. 1, 01.2016, p. 168-241.

Research output: Contribution to journalReview ArticleScientificpeer-review

TY - JOUR

T1 - Role of Cytochrome P450 2C8 in Drug Metabolism and Interactions

AU - Backman, Janne T.

AU - Filppula, Anne M.

AU - Niemi, Mikko

AU - Neuvonen, Pertti J.

PY - 2016/1

Y1 - 2016/1

KW - HUMAN LIVER-MICROSOMES

KW - IN-VITRO METABOLISM

KW - HMG-COA REDUCTASE

KW - MECHANISM-BASED INACTIVATION

KW - HUMAN HEPATIC MICROSOMES

KW - BISPHOSPHONATE-RELATED OSTEONECROSIS

KW - TIME-DEPENDENT INHIBITION

KW - TANDEM MASS-SPECTROMETRY

KW - SINGLE-NUCLEOTIDE POLYMORPHISMS

KW - FLAVIN-CONTAINING MONOOXYGENASE

KW - 3111 Biomedicine

U2 - 10.1124/pr.115.011411

DO - 10.1124/pr.115.011411

M3 - Review Article

VL - 68

SP - 168

EP - 241

JO - Pharmacological Reviews

JF - Pharmacological Reviews

SN - 0031-6997

IS - 1

ER -